A novel electrochemical platform for assay of alkaline phosphatase based on amifostine and ATRP signal amplification

Article Biochemistry & Molecular Biology

Electrochemical detection of alkaline phosphatase activity via atom transfer radical polymerization

Xiaofei Li et al.

Summary: An electrochemical method for detecting ALP activity through ARGET ATRP was developed in this study, showing good analytical performance and promising applications.

BIOELECTROCHEMISTRY (2022)

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Article Chemistry, Analytical

Restoring the Oxidase-Like Activity of His@AuNCs for the Determination of Alkaline Phosphatase

Fanfan Xiao et al.

Summary: The paper presents a simple colorimetric method based on the oxidase mimic activity of His@AuNCs for the sensitive and selective detection of alkaline phosphatase (ALP) activity, with a detection range of 0-40 mU/mL and a detection limit of 0.26 mU/mL. The method is fast, easy, and suitable for accurately and effectively monitoring ALP activity in serum samples.

BIOSENSORS-BASEL (2021)

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Article Chemistry, Analytical

Grafting of polymers via ring-opening polymerization for electrochemical assay of alkaline phosphatase activity

Xin Zhu et al.

Summary: A novel electrochemical sensor based on signal amplification strategy through ring-opening polymerization (ROP) has been developed for the assay of alkaline phosphatase (ALP) activity. The sensor showed satisfactory linear dependence, low detection limit, and good selectivity in human serum samples, with a relative error of less than 5% compared to clinical data.

ANALYTICA CHIMICA ACTA (2021)

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Article Chemistry, Analytical

Facile preparation of red emission Hg-doped ZnSe QDs and ratiometric determination of alkaline phosphatase based on in situ generation of dual fluorescent reporter

Junyang Chen et al.

Summary: This study prepared highly red emissive mercury-doped zinc selenide quantum dots and designed a ratio fluorometric technique for ultra-sensitive detection of alkaline phosphatase activity. The novel nanoprobe utilizing Hg-doped ZnSe QDs and QXD as dual fluorescent reporter enables visual detection of ALP activity and shows satisfactory results for measuring ALP activity in human serum.

SENSORS AND ACTUATORS B-CHEMICAL (2021)

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Article Biochemical Research Methods

Sensitive colorimetric assay for the determination of alkaline phosphatase activity utilizing nanozyme based on copper nanoparticle-modified Prussian blue

Shengnan Fan et al.

Summary: Cu@PB NCs exhibit enhanced POD-like activity compared to PB NCs and HRP, and can be utilized for colorimetric assay of ALP activity by oxidizing TMB in the presence of H2O2. Introduction of PPi results in decreased POD-like activity of Cu@PB NCs, while ALP hydrolyzes PPi and restores the activity of Cu@PB NCs.

ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2021)

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Article Chemistry, Analytical

Simultaneous sensing γ-glutamyl transpeptidase and alkaline phosphatase by robust dual-emission carbon dots

Xia Tong et al.

Summary: A new strategy based on dual-emission carbon dots has been developed for simultaneous monitoring of GGT and ALP activity, showing high sensitivity and wide linear ranges. Detection of GGT and ALP activity can be achieved through IFE and SQE of blue and red channels of CDs, meeting the monitoring needs in human serum samples.

ANALYTICA CHIMICA ACTA (2021)

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Article Chemistry, Analytical

A novel signal-on photoelectrochemical platform for highly sensitive detection of alkaline phosphatase based on dual Z-scheme CdS/Bi2S3/BiOCl composites

Ling Dan Yu et al.

Summary: This study introduces a dual Z-scheme photoelectronic material, CdS/Bi2S3/BiOCl, with great PEC performance. The catalytic production of electron donor inhibits the recombination of photo-induced electrons and holes, resulting in increased photocurrent.

SENSORS AND ACTUATORS B-CHEMICAL (2021)

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Article Chemistry, Analytical