Journal
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
Volume 414, Issue 24, Pages 7015-7022Publisher
SPRINGER HEIDELBERG
DOI: 10.1007/s00216-022-04163-8
Keywords
Certified reference material (CRM); Standard reference material (SRM); Metabolomics; Lipidomics; Method validation; Environmental contaminants
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Certified reference materials (CRMs) are important tools for validating analytical methods and demonstrating quality, but their use is often overlooked in analytical chemistry journals. This article explores the potential benefits of using CRMs, even without certified values.
Certified reference materials (CRMs) are routinely used by analytical chemists to validate new analytical methods and to demonstrate the quality of their quantitative measurements. Even though CRMs for trace element and trace organic analysis have been available and widely used for over 50 years, the majority of papers published in analytical chemistry journals do not mention the use of CRMs. What if analytical/bioanalytical chemistry journals required the use of CRMs to publish a paper? This feature article attempts to address this question by providing examples of recent papers that have made exceptional use of CRMs to validate new analytical methods and to describe novel, alternative uses of CRMs that provide new characterization of the CRM. The potential benefits of using a CRM even when it does not have certified values for the analytes of interest are presented.
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