4.4 Article

Automatic classification of the obstruction site in obstructive sleep apnea based on snoring sounds

Journal

AMERICAN JOURNAL OF OTOLARYNGOLOGY
Volume 43, Issue 6, Pages -

Publisher

W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.amjoto.2022.103584

Keywords

Obstructive sleep apnea; Obstruction site; Drug -induced sleep endoscopy; Machine learning

Funding

  1. National Key Research and Development Program of China [2018YFC0116800]
  2. Natural Science Foundation of China [81970866]
  3. Shenzhen Science and Technology Innovation Commission: Key Projects of Stable Funding for Universities [WDZC 20200818121348001]
  4. Shenzhen Science and Technology Innovation Commission: Sustainable Development Project [KCXFZ202002011010487]

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A machine learning-based model was developed to detect obstruction site using snoring sound, showing high accuracy in detecting different obstruction sites, especially when combined with age, gender, and BMI.
Objectives: Snoring is a common symptom of obstructive sleep apnea (OSA) which is considered to be potential predictors of the obstruction site. Successful treatment of OSA depend on the determination the types of obstruction site. This study aimed to develop a machine learning-based model to detect obstruction site using snoring sound.Methods: Patients with OSA underwent drug-induced sleep endoscopy (DISE) and the snoring sounds were recorded simultaneously. We extracted acoustic features based on Mel-frequency cepstral coefficients (MFCC). A k-nearest neighbors (KNN) was used for snore classification.Results: Total 42 patients with OSA were enrolled. The accuracy of model was 85.55 %, F1 score was 85.04. With combined age, gender and Body Mass Index (BMI), the accuracy of model was 87.98 %, and F1 score was 87.96. The model exhibited accuracies of 83 %, 93 % and 92 %; an AUC of 85.88, 89.22 and 88.17 in detecting ret-ropalatal, retrolingual and multilevel obstructions.Conclusion: Our results suggest that combing snoring sound with age, gender and BMI, the machine learning based model can help automatically assess obstruction site. The model may have potential utility as a clinical tool to help for clinical decision-making.

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