4.6 Article

Modeling the impact of COVID-19 pandemic-driven increases in alcohol consumption on health outcomes and hospitalization costs in the United States

Journal

ADDICTION
Volume 118, Issue 1, Pages 48-60

Publisher

WILEY
DOI: 10.1111/add.16018

Keywords

alcohol consumption; alcohol-related liver disease; alcohol-related hospitalizations; alcohol use disorder; alcohol-related morbidity and mortality; COVID-19; health utility; hospitalization cost; simulation model

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The increase in alcohol consumption during the COVID-19 pandemic in the United States may lead to significant health and cost impacts. Short-term increases in drinking result in a loss of life years, quality-adjusted life years, and an increase in alcohol-related hospitalizations and costs. Older individuals, women, and non-Hispanic black individuals are more affected. If the increased drinking levels persist, the impacts will be even greater in the long term.
Background and aims Alcohol consumption increased in the early phases of the COVID-19 pandemic in the United States. Alcohol use disorder (AUD) and risky drinking are linked to harmful health effects. This paper aimed to project future health and cost impacts of shifts in alcohol consumption during the COVID-19 pandemic. Design An individual-level simulation model of the long-term drinking patterns for people with life-time AUD was used to simulate 10 000 individuals and project model outcomes to the estimated 25.9 million current drinkers with life-time AUD in the United States. The model considered three scenarios: (1) no change (counterfactual for comparison); (2) increased drinking levels persist for 1 year ('increase-1') and (3) increased drinking levels persist for 5 years ('increase-5'). Setting United States. Participants Current drinkers with life-time AUD. Measurements Life expectancy [life-years (LYs)], quality-adjusted life-years (QALYs), alcohol-related hospitalizations and associated hospitalization costs and alcohol-related deaths, during a 5-year period. Findings Short-term increases in alcohol consumption (increase-1 scenario) resulted in a loss of 79 000 [95% uncertainty interval (UI]) 26 000-201 000] LYs, a loss of 332 000 (104 000-604 000) QALYs and 295 000 (82 000-501 000) more alcohol-related hospitalizations, costing an additional $5.4 billion ($1.5-9.3 billion) over 5 years. Hospitalizations for cirrhosis of the liver accounted for approximately $3.0 billion ($0.9-4.8 billion) in hospitalization costs, more than half the increase across all alcohol-related conditions. Health and cost impacts were more pronounced for older age groups (51+), women and non-Hispanic black individuals. Increasing the duration of pandemic-driven increases in alcohol consumption in the increase-5 scenario resulted in larger impacts. Conclusions Simulations show that if the increase in alcohol consumption observed in the United States in the first year of the pandemic continues, alcohol-related mortality, morbidity and associated costs will increase substantially over the next 5 years.

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