4.8 Article

Long-Term Storage Stability and Nitric Oxide Release Behavior of (N-Acetyl-S-nitrosopenicillaminyl)-S-nitrosopenicillamine-Incorporated Silicone Rubber Coatings

Related references

Note: Only part of the references are listed.
Article Engineering, Biomedical

Prevention of medical device infections via multi-action nitric oxide and chlorhexidine diacetate releasing medical grade silicone biointerfaces

Manjyot Kaur Chug et al.

Summary: This study evaluated the synergy of nitric oxide (NO) and chlorhexidine diacetate (CHXD) to create an antimicrobial medical-grade silicone rubber. The results showed that the dual-active SNAP-CHXD films were able to significantly reduce Escherichia coli and Staphylococcus aureus bacteria without toxicity towards mouse fibroblast cells.

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A (2022)

Article Nanoscience & Nanotechnology

Improved Polymer Hemocompatibility for Blood-Contacting Applications via S-Nitrosoglutathione Impregnation

Lauren Griffin et al.

Summary: This paper reports a novel BCMD technology that uses S-nitrosoglutathione impregnated poly(vinyl chloride) tubing to mimic the antithrombotic properties of the human vasculature. The study demonstrates the blood compatibility of the material and its ability to reduce platelet activation through in vitro and in vivo experiments.

ACS APPLIED MATERIALS & INTERFACES (2022)

Article Nanoscience & Nanotechnology

Nitric Oxide-Releasing Lock Solution for the Prevention of Catheter-Related Infection and Thrombosis

Morgan Ashcraft et al.

Summary: This study reports the development of a dual-functional lock therapy using a nitric oxide donor molecule, S-nitrosoglutathione, to prevent infection and thrombosis associated with venous catheters. The therapy outperforms traditional antibiotic lock solutions in preventing catheter infections and also inhibits clot formation. It has excellent potential for safely and effectively reducing complications related to catheter usage.

ACS APPLIED BIO MATERIALS (2022)

Article Biochemistry & Molecular Biology

S-Nitrosoglutathione-Based Nitric Oxide-Releasing Nanofibers Exhibit Dual Antimicrobial and Antithrombotic Activity for Biomedical Applications

Megan Douglass et al.

Summary: The novel use of nanofibers coated with nitric oxide releasing biodegradable polymers provides a safe antimicrobial and hemocompatible coating for blood-contacting medical devices. The nanofibers exhibit improved mechanical properties, significant reduction in bacterial adhesion, and decreased platelet adhesion, making them suitable for various biomedical applications.

MACROMOLECULAR BIOSCIENCE (2021)

Article Nanoscience & Nanotechnology

Surface-Catalyzed Nitric Oxide Release via a Metal Organic Framework Enhances Antibacterial Surface Effects

Mark Garren et al.

Summary: The combination of metal organic frameworks (MOFs) and NO donors can effectively accelerate the release rate of NO for therapeutic applications, preventing biofilm formation on medical devices. Through intrapolymeric interactions, tunable NO surface fluxes can elicit different cytotoxic responses in human cell lines, showing potential for application-specific tailoring. Enhanced NO release from the composite materials was found to significantly reduce bacterial growth, indicating a promising approach for combating opportunistic bacteria.

ACS APPLIED MATERIALS & INTERFACES (2021)

Article Nanoscience & Nanotechnology

Reduction in Foreign Body Response and Improved Antimicrobial Efficacy via Silicone-Oil-Infused Nitric-Oxide-Releasing Medical-Grade Cannulas

Megan Douglass et al.

Summary: The study demonstrates that impregnating NO donor and silicone oil into silicone rubber cannulas can effectively improve antimicrobial properties, reduce foreign body response, and show enhanced biocompatibility in in vivo experiments. This approach may contribute to extending the lifetime and safety of indwelling medical devices.

ACS APPLIED MATERIALS & INTERFACES (2021)

Article Chemistry, Medicinal

Exogenous Nitric Oxide Improves Antibiotic Susceptibility in Resistant Bacteria

Kaitlyn R. Rouillard et al.

Summary: Antibiotic resistance in bacteria is a major global threat, especially for patients with cystic fibrosis who are frequently colonized by multidrug-resistant species. Research has shown that nitric oxide can act as a broad-spectrum antibacterial agent, improving the effectiveness of conventional antibiotics and slowing the development of antibiotic resistance.

ACS INFECTIOUS DISEASES (2021)

Article Nanoscience & Nanotechnology

S-Nitroso-N-acetyl-L-cysteine Ethyl Ester (SNACET) Catheter Lock Solution to Reduce Catheter-Associated Infections

Rajnish Kumar et al.

Summary: Antimicrobial-lock therapy is an economically viable strategy to prevent catheter-related bloodstream infections. SNACET lock solution shows promising potential in reducing bacterial adhesion and inhibiting catheter-related infections through its tunable nitric oxide release capability.

ACS APPLIED MATERIALS & INTERFACES (2021)

Article Nanoscience & Nanotechnology

Mimicking the Endothelium: Dual Action Heparinized Nitric Oxide Releasing Surface

Ryan Devine et al.

ACS APPLIED MATERIALS & INTERFACES (2020)

Review Chemistry, Multidisciplinary

Metal-Based Nanoparticles as Antimicrobial Agents: An Overview

Elena Sanchez-Lopez et al.

NANOMATERIALS (2020)

Review Biotechnology & Applied Microbiology

The Toxicity Phenomenon and the Related Occurrence in Metal and Metal Oxide Nanoparticles: A Brief Review From the Biomedical Perspective

Shokouh Attarilar et al.

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2020)

Article Materials Science, Biomaterials

Liquid-Infused Nitric-Oxide-Releasing Silicone Foley Urinary Catheters for Prevention of Catheter-Associated Urinary Tract Infections

Katie H. Homeyer et al.

ACS BIOMATERIALS SCIENCE & ENGINEERING (2019)

Article Biochemistry & Molecular Biology

Controlled light-induced gas phase nitric oxide release from S-nitrosothiol-doped silicone rubber films

Gergely Lautner et al.

NITRIC OXIDE-BIOLOGY AND CHEMISTRY (2019)

Article Nanoscience & Nanotechnology

Active Release of an Antimicrobial and Antiplatelet Agent from a Nonfouling Surface Modification

Marcus J. Goudie et al.

ACS APPLIED MATERIALS & INTERFACES (2019)

Article Nanoscience & Nanotechnology

Extended Nitric Oxide-Releasing Polyurethanes via S-Nitrosothiol-Modified Mesoporous Silica Nanoparticles

Maggie J. Malone-Povolny et al.

ACS APPLIED MATERIALS & INTERFACES (2019)

Article Chemistry, Multidisciplinary

Synthesis and nitric oxide releasing properties of novel fluoro S-nitrosothiols

Yang Zhou et al.

CHEMICAL COMMUNICATIONS (2019)

Article Nanoscience & Nanotechnology

Increasing the Lifetime of Insulin Cannula with Antifouling and Nitric Oxide Releasing Properties

Manjyot Kaur Chug et al.

ACS APPLIED BIO MATERIALS (2019)

Article Materials Science, Biomaterials

Biodegradable crosslinked polyesters derived from thiomalic acid and S-nitrosothiol analogues for nitric oxide release

Janet P. Yapor et al.

JOURNAL OF MATERIALS CHEMISTRY B (2018)

Review Materials Science, Biomaterials

Recent advances in nitric oxide delivery for antimicrobial applications using polymer-based systems

Zahra Sadrearhami et al.

JOURNAL OF MATERIALS CHEMISTRY B (2018)

Review Chemistry, Multidisciplinary

Progress and Promise of Nitric Oxide-Releasing Platforms

Tao Yang et al.

ADVANCED SCIENCE (2018)

Article Biochemical Research Methods

Antibacterial Activity of Nitric Oxide-Releasing Hyperbranched Polyamidoamines

Lei Yang et al.

BIOCONJUGATE CHEMISTRY (2018)

Article Nanoscience & Nanotechnology

Nitric Oxide-Releasing Hyperbranched Polyaminoglycosides for Antibacterial Therapy

Lei Yang et al.

ACS APPLIED BIO MATERIALS (2018)

Review Nanoscience & Nanotechnology

Antibacterial properties and toxicity from metallic nanomaterials

Gina V. Vimbela et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2017)

Article Materials Science, Biomaterials

Enhanced antibacterial efficacy of nitric oxide releasing thermoplastic polyurethanes with antifouling hydrophilic topcoats

Priyadarshini Singha et al.

BIOMATERIALS SCIENCE (2017)

Article Nanoscience & Nanotechnology

Tunable Nitric Oxide Release from S-Nitroso-N-acetylpenicillamine via Catalytic Copper Nanoparticles for Biomedical Applications

Jitendra Pant et al.

ACS APPLIED MATERIALS & INTERFACES (2017)

Review Critical Care Medicine

IMPLANTABLE DEVICE-RELATED INFECTION

J. Scott VanEpps et al.

SHOCK (2016)

Article Materials Science, Biomaterials

Nitric oxide release from a biodegradable cysteine-based polyphosphazene

Alec Lutzke et al.

JOURNAL OF MATERIALS CHEMISTRY B (2016)

Article Materials Science, Biomaterials

Active Release of Nitric Oxide-Releasing Dendrimers from Electrospun Polyurethane Fibers

Brittany V. Worley et al.

ACS BIOMATERIALS SCIENCE & ENGINEERING (2016)

Article Materials Science, Biomaterials

Active Release of Nitric Oxide-Releasing Dendrimers from Electrospun Polyurethane Fibers

Brittany V. Worley et al.

ACS BIOMATERIALS SCIENCE & ENGINEERING (2016)

Review Pharmacology & Pharmacy

Antibiotic-containing polymers for localized, sustained drug delivery

Nicholas D. Stebbins et al.

ADVANCED DRUG DELIVERY REVIEWS (2014)

Article Materials Science, Biomaterials

Nitric oxide-releasing S-nitrosated derivatives of chitin and chitosan for biomedical applications

Alec Lutzke et al.

JOURNAL OF MATERIALS CHEMISTRY B (2014)

Article Chemistry, Multidisciplinary

Polymer-Based Nitric Oxide Therapies: Recent Insights for Biomedical Applications

Michele C. Jen et al.

ADVANCED FUNCTIONAL MATERIALS (2012)

Article Health Care Sciences & Services

Economic burden of healthcare-associated infections: an American perspective

Patricia W Stone

Expert Review of Pharmacoeconomics & Outcomes Research (2009)

Review Biotechnology & Applied Microbiology

Medical Biofilms

James D. Bryers

BIOTECHNOLOGY AND BIOENGINEERING (2008)

Article Biochemistry & Molecular Biology

Interactions between nitric oxide, oxygen, reactive oxygen species and reactive nitrogen species

G. C. Brown et al.

BIOCHEMICAL SOCIETY TRANSACTIONS (2006)