Journal
JOURNAL OF CLINICAL MICROBIOLOGY
Volume 54, Issue 3, Pages 805-808Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.03032-15
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- HHS \ NIH \ National Institute of Allergy and Infectious Diseases (NIAID) [R21AI109005]
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In the United States, 19.2% of Neisseria gonorrhoeae isolates are resistant to ciprofloxacin. We evaluated a real-time PCR assay to predict ciprofloxacin susceptibility using residual DNA from the Roche Cobas 4800 CT/NG assay. The results of the assay were 100% concordant with agar dilution susceptibility test results for 100 clinical isolates. Among 76 clinical urine and swab specimens positive for N. gonorrhoeae by the Cobas assay, 71% could be genotyped. The test took 1.5 h to perform, allowing the physician to receive results in time to make informed clinical decisions.
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