Detection of New Delhi Metallo-Beta-Lactamase (Encoded by blaNDM-1) in Enterobacter aerogenes in China

BackgroundThe increase in bla(NDM-1) in Enterobacteriaceae has become a major concern worldwide. In previous study, we investigated clonal dissemination and mechanisms of resistance to carbapenem in China. MethodsWe carried out retrospective surveillance for bla(NDM-1) among carbapenem-resistant enterobacter strains, which were isolated from patients at our hospital by bacterial strains selection, antimicrobial susceptibility testing, species identification, and molecular detection of resistance gene. ResultsWe found three bla(NDM-1)-positive isolates which were identified as Enterobacter aerogenes in clinical patients in China. The bla(NDM-1)-positive Enterobacter aerogenes isolates were first found. ConclusionIt is important to mandate prudent usage of antibiotics and implement infection control measures to control the spread of these resistant bla(NDM-1)-positive strains.