Journal
CURRENT CANCER THERAPY REVIEWS
Volume 18, Issue 2, Pages 80-86Publisher
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1573394718666220329184532
Keywords
Nanoparticles; cancer targeting; biodegradable polymer; chemotherapy; nanodelivery; EPR
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This review article provides a brief overview of the advancements in cancer treatment through nanodelivery systems. The benefits of various nanocarriers and the targeted drug delivery approach are discussed, highlighting the selectivity and safety characteristics of nanodelivery systems compared to conventional drug delivery. The review also covers different targeting strategies, characteristics of ideal drug delivery systems, advantages of these systems, and future prospects.
This review article gives a brief account of advances in the treatment of cancer via nanodelivery systems. We have discussed benefits of different nanocarriers that have the potential to deal with the problem of non-selectivity of conventional anticancer drugs. Targeted drug delivery not only spares healthy cells from harmful effects of anticancer drugs but also reduces the amount of drug to be administered; various drug delivery systems have been fabricated using appropriate nanocarriers. In fact, some carrier systems are biodegradable and degrade in the body into nontoxic moieties, thereby adding safety characteristics to the formulation. Selectivity towards cancer cells makes nanodelivery system a choice for the treatment of cancer as compared to conventional drug delivery. This review discusses various targeting strategies, different nanodelivery systems, characteristics required to be an ideal drug delivery system, advantages of these systems, and future prospects of such systems.
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