3.8 Article

BIOLOGICAL ACTIVITY OF ESSENTIAL SAGE OIL

Journal

JOURNAL OF SCIENCE AND ARTS
Volume -, Issue 1, Pages 211-218

Publisher

EDITURA BIBLIOTHECA-BIBLIOTHECA PUBL HOUSE
DOI: 10.46939/J.Sci.Arts-22.1-b02

Keywords

sage oil; phenolic compounds; antioxidant activity; antibacterial activity; Staphylococcus sp; Enterococcus sp

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Essential sage oil was obtained from dry leaves through steam distillation. Chemical analysis revealed high polyphenolic content and strong antioxidant activity. The oil also exhibited significant antibacterial activity against both Gram-positive and Gram-negative bacterial strains.
Essential sage oil (ESO) was isolated from dry leaves by steam distillation with Neo-Clevenger apparatus. The chemical analysis of the ESO consisted in the assessment of the total polyphenolic content (Folin-Ciocalteu method) and of the radical scavenging activity with DPPH. The antioxidant activity was measured using two standard compounds: gallic acid and ascorbic acid. Phenolic content of essential oil of S. officinalis was significant (15.465 mg GAE/g oil) and antioxidant activity was high. Antibacterial activity of essential sage oil was evaluated against Gram positive and Gram-negative bacterial strains isolated from clinical specimens. The sage oil showed significant but variable antibacterial activity with inhibition zones ranging from 4 mm to 9.5.mm. The effect was stronger on Gram positive (Enterococcus, Staplylococcus) than Gram negative bacteria (Escherichia sp, Proteus sp, Klebsiella sp).

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