Journal
BOLETIN MEDICO DEL HOSPITAL INFANTIL DE MEXICO
Volume 79, Issue 2, Pages 83-90Publisher
HOSPITAL INFANTIL MEXICO
DOI: 10.24875/BMHIM.21000088
Keywords
Diet; Acne vulgaris; Glycemic index; Glycemic load
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Acne is a chronic inflammatory disease with multifactorial causes. Besides factors such as abnormal keratinocyte proliferation, altered sebum production, and bacterial colonization, diet is also associated with the development, severity, and response to treatment of acne.
Acne is a chronic inflammatory disease of the pilosebaceous unit with multifactorial etiology. Abnormal proliferation of keratinocytes, altered sebum production, inflammation of the sebaceous follicle, and colonization by Cutibacterium acnes have been traditionally implicated. However, the diet has also been highlighted in the pathogenesis because of its direct relation with some biochemical markers and the transcription of specific genes associated with sebaceous gland activity, inflammation, and bacterial proliferation, which together promote the development of the disease, affect the severity of the condition, and modify its response to treatment.
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