Management of scleroderma gastrointestinal disease: Lights and shadows

Gastrointestinal symptoms affect the great majority of patients with systemic sclerosis. Management of these complications is often challenging as any region of the gastrointestinal tract may be involved, and significant heterogeneity exists in clinical presentation, kinetics, and outcomes. Here, we highlight new findings relevant to the management of systemic sclerosis-related gastrointestinal disease (lights) and consider areas that we have yet to elucidate (shadows).

Automated summary

Gastrointestinal symptoms are common in patients with systemic sclerosis, and managing these complications can be challenging due to the variability in clinical presentation. New findings related to the management of systemic sclerosis-related gastrointestinal disease are highlighted, with areas for further elucidation still remaining.