High-density neural recording system design

Implantable medical devices capable of monitoring hundreds to thousands of electrodes have received great attention in biomedical applications for understanding of the brain function and to treat brain diseases such as epilepsy, dystonia, and Parkinson's disease. Non-invasive neural recording modalities such as fMRI and EEGs were widely used since the 1960s, but to acquire better information, invasive modalities gained popularity. Since such invasive neural recording system requires high efficiency and low power operation, they have been implemented as integrated circuits. Many techniques have been developed and applied when designing integrated high-density neural recording architecture for better performance, higher efficiency, and lower power consumption. This paper covers general knowledge of neural signals and frequently used neural recording architectures for monitoring neural activity. For neural recording architecture, various neural recording amplifier structures are covered. In addition, several neural processing techniques, which can optimize the neural recording system, are also discussed.

Automated summary

Implantable medical devices for monitoring brain activity have become popular due to their ability to provide better information compared to non-invasive methods. Integrated circuits have been developed to ensure high efficiency and low power operation of these invasive neural recording systems. This paper provides an overview of neural signals, neural recording architectures, and techniques for optimizing the system.