Acute liver failure due to hepatitis B virus reactivation induced by doxorubicin and cyclophosphamide chemotherapy for adjuvant treatment of breast cancer: A case report

Acute liver failure developed in a 48-year-old woman within days after she received adjuvant chemotherapy for breast cancer. On arrival at ED, she had severe encephalopathy and jaundice. Serum analyses demonstrated coagulopathy and markedly increased transaminases. She was admitted to the ICU for supportive treatment but died several days later.

Automated summary

A 48-year-old woman developed acute liver failure within days after receiving adjuvant chemotherapy for breast cancer. On arrival at the emergency department, she presented with severe encephalopathy and jaundice. Serum analyses showed coagulopathy and significantly increased transaminases. She was admitted to the intensive care unit (ICU) for supportive treatment but died several days later.