4.4 Article

Prevalence and predictors of uncontrolled hypertension, diabetes, and obesity among adults with HIV in northern Tanzania

Journal

GLOBAL PUBLIC HEALTH
Volume 17, Issue 12, Pages 3747-3759

Publisher

ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD
DOI: 10.1080/17441692.2022.2049344

Keywords

Sub-Saharan Africa; HIV; hypertension; diabetes mellitus; obesity

Funding

  1. Duke University Center for AIDS Research (CFAR), an National Institutes of Health [P30 AI064518]

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In this study, the researchers examined the cardiovascular comorbidities among people with HIV in Tanzania. The results showed a high prevalence of hypertension, diabetes, and obesity among the participants, with a majority of them having uncontrolled hypertension. Older age and higher body mass index were associated with uncontrolled hypertension.
HIV is associated with increased risk of cardiovascular disease, but there has been less study of cardiovascular comorbidities among people with HIV in sub-Saharan Africa. In a cross-sectional observational study, Tanzanian adults presenting for outpatient HIV care completed a questionnaire and underwent weight, height, blood pressure, and blood glucose measurement. Hypertension was defined by blood pressure >= 140/90 mmHg or self-reported hypertension. Uncontrolled hypertension was defined as measured blood pressure >= 140/90 mmHg. Diabetes was defined by fasting glucose >= 126 mg/dl, random glucose >= 200 mg/dl, or self-reported diabetes. Obesity was defined by body mass index >= 30 kg/m(2). Multivariate logistic regression was performed to identify predictors of uncontrolled hypertension. Among 500 participants, 173 (34.6%) had hypertension, 21 (4.2%) had diabetes, and 99 (19.8%) were obese. Of those with hypertension, 116 (67.1%) were unaware of their hypertension, and 155 (89.6%) had uncontrolled hypertension. In multivariate analysis, uncontrolled hypertension was associated with older age (OR 1.07, 95% CI: 1.05-1.10, p < 0.001) and higher body mass index (OR 1.17, 95% CI: 1.11-1.22, p < 0.001). Interventions are needed to improve screening and treatment for hypertension, diabetes, and obesity among Tanzanians with HIV.

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