Related references
Note: Only part of the references are listed.Knock-out of nexilin in mice leads to dilated cardiomyopathy and endomyocardial fibroelastosis
Zouhair Aherrahrou et al.
BASIC RESEARCH IN CARDIOLOGY (2016)
Modeling structural and functional deficiencies of RBM20 familial dilated cardiomyopathy using human induced pluripotent stem cells
Saranya P. Wyles et al.
HUMAN MOLECULAR GENETICS (2016)
A mouse model for adult cardiac-specific gene deletion with CRISPR/Cas9
Kelli J. Carroll et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Mutations in FLNC are Associated with Familial Restrictive Cardiomyopathy
Andreas Brodehl et al.
HUMAN MUTATION (2016)
The coiled-coil domain of MURC/cavin-4 is involved in membrane trafficking of caveolin-3 in cardiomyocytes
Daisuke Naito et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2015)
Nebulette knockout mice have normal cardiac function, but show Z-line widening and up-regulation of cardiac stress markers
Giuseppina Mastrototaro et al.
CARDIOVASCULAR RESEARCH (2015)
Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy - Three Decades of Progress
Hugh Calkins
CIRCULATION JOURNAL (2015)
Loss of Cardiomyocyte Integrin-Linked Kinase Produces an Arrhythmogenic Cardiomyopathy in Mice
Khai Le Quang et al.
CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY (2015)
Myofibrillar instability exacerbated by acute exercise in filaminopathy
Frederic Chevessier et al.
HUMAN MOLECULAR GENETICS (2015)
BAG3 myofibrillar myopathy presenting with cardiomyopathy
Chamindra G. Konersman et al.
NEUROMUSCULAR DISORDERS (2015)
Titin mutations in iPS cells define sarcomere insufficiency as a cause of dilated cardiomyopathy
John T. Hinson et al.
SCIENCE (2015)
The toxic effect of R350P mutant desmin in striated muscle of man and mouse
Christoph S. Clemen et al.
ACTA NEUROPATHOLOGICA (2015)
A mutation in the Z-line Cypher/ZASP protein is associated with arrhythmogenic right ventricular cardiomyopathy
J. M. Lopez-Ayala et al.
CLINICAL GENETICS (2015)
Fhl1 W122S causes loss of protein function and late-onset mild myopathy
Valentina Emmanuele et al.
HUMAN MOLECULAR GENETICS (2015)
OBSCN Mutations Associated with Dilated Cardiomyopathy and Haploinsufficiency
Steven Marston et al.
PLOS ONE (2015)
Exome sequencing identifies a mutation in the ACTN2 gene in a family with idiopathic ventricular fibrillation, left ventricular noncompaction, and sudden death
Richard D. Bagnall et al.
BMC MEDICAL GENETICS (2014)
CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling
Randall J. Platt et al.
CELL (2014)
Inherited Cardiomyopathies
Jeffrey A. Towbin
CIRCULATION JOURNAL (2014)
Gigantic Business Titin Properties and Function Through Thick and Thin
Wolfgang A. Linke et al.
CIRCULATION RESEARCH (2014)
Muscle lim protein isoform negatively regulates striated muscle actin dynamics and differentiation
Elizabeth Vafiadaki et al.
FEBS JOURNAL (2014)
Combination of Genetic Screening and Molecular Dynamics as a Useful Tool for Identification of Disease-Related Mutations: ZASP PDZ Domain G54S Mutation Case
Filip Fratev et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2014)
Disturbance in Z-Disk Mechanosensitive Proteins Induced by a Persistent Mutant Myopalladin Causes Familial Restrictive Cardiomyopathy
Anne-Cecile Huby et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2014)
Human Muscle LIM Protein Dimerizes along the Actin Cytoskeleton and Cross-Links Actin Filaments
Celine Hoffmann et al.
MOLECULAR AND CELLULAR BIOLOGY (2014)
ZASP Interacts with the Mechanosensing Protein Ankrd2 and p53 in the Signalling Network of Striated Muscle
Valentina C. Martinelli et al.
PLOS ONE (2014)
MURC/Cavin-4 facilitates recruitment of ERK to caveolae and concentric cardiac hypertrophy induced by α1-adrenergic receptors
Takehiro Ogata et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Deleting titin's I-band/A-band junction reveals critical roles for titin in biomechanical sensing and cardiac function
Henk L. Granzier et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Mutations in filamin C cause a new form of familial hypertrophic cardiomyopathy
Rafael Valdes-Mas et al.
NATURE COMMUNICATIONS (2014)
Desminopathies: pathology and mechanisms
Christoph S. Clemen et al.
ACTA NEUROPATHOLOGICA (2013)
Pathogenesis of hypertrophic cardiomyopathy caused by myozenin 2 mutations is independent of calcineurin activity
Alessandra Ruggiero et al.
CARDIOVASCULAR RESEARCH (2013)
Abnormal Calcium Handling Properties Underlie Familial Hypertrophic Cardiomyopathy Pathology in Patient-Specific Induced Pluripotent Stem Cells
Feng Lan et al.
CELL STEM CELL (2013)
Shortening of the Elastic Tandem Immunoglobulin Segment of Titin Leads to Diastolic Dysfunction
Charles S. Chung et al.
CIRCULATION (2013)
Generation of patient-specific induced pluripotent stem cell-derived cardiomyocytes as a cellular model of arrhythmogenic right ventricular cardiomyopathy
Dongrui Ma et al.
EUROPEAN HEART JOURNAL (2013)
Novel mutations in the sarcomeric protein myopalladin in patients with dilated cardiomyopathy
Thomas Meyer et al.
EUROPEAN JOURNAL OF HUMAN GENETICS (2013)
Patient-specific induced-pluripotent stem cells-derived cardiomyocytes recapitulate the pathogenic phenotypes of dilated cardiomyopathy due to a novel DES mutation identified by whole exome sequencing
Hung-Fat Tse et al.
HUMAN MOLECULAR GENETICS (2013)
Cypher/ZASP Is a Novel A-kinase Anchoring Protein
Changsong Lin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Mutations in the Paxillin-binding Site of Integrin-linked Kinase (ILK) Destabilize the Pseudokinase Domain and Cause Embryonic Lethality in Mice
Daniel Moik et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Genetic mutations and mechanisms in dilated cardiomyopathy
Elizabeth M. McNally et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
Altered regional cardiac wall mechanics are associated with differential cardiomyocyte calcium handling due to nebulette mutations in preclinical inherited dilated cardiomyopathy
K. Maiellaro-Rafferty et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2013)
Inherited Cardiomyopathies Molecular Genetics and Clinical Genetic Testing in the Postgenomic Era
Polakit Teekakirikul et al.
JOURNAL OF MOLECULAR DIAGNOSTICS (2013)
Identification of Xin-repeat proteins as novel ligands of the SH3 domains of nebulin and nebulette and analysis of their interaction during myofibril formation and remodeling
Stefan Eulitz et al.
MOLECULAR BIOLOGY OF THE CELL (2013)
Studying arrhythmogenic right ventricular dysplasia with patient-specific iPSCs
Changsung Kim et al.
NATURE (2013)
RNA-Guided Human Genome Engineering via Cas9
Prashant Mali et al.
SCIENCE (2013)
Cardiac remodeling is not modulated by overexpression of muscle LIM protein (MLP)
Christian Kuhn et al.
BASIC RESEARCH IN CARDIOLOGY (2012)
Outcomes of Restrictive Cardiomyopathy in Childhood and the Influence of Phenotype A Report From the Pediatric Cardiomyopathy Registry
Steven A. Webber et al.
CIRCULATION (2012)
BAG3-related myofibrillar myopathy in a Chinese family
H. C. Lee et al.
CLINICAL GENETICS (2012)
α-Actinin-2 deficiency results in sarcomeric defects in zebrafish that cannot be rescued by α-actinin-3 revealing functional differences between sarcomeric isoforms
Vandana Gupta et al.
FASEB JOURNAL (2012)
Molecular basis for clinical heterogeneity in inherited cardiomyopathies due to myopalladin mutations
Enkhsaikhan Purevjav et al.
HUMAN MOLECULAR GENETICS (2012)
Evidence for FHL1 as a novel disease gene for isolated hypertrophic cardiomyopathy
Felix W. Friedrich et al.
HUMAN MOLECULAR GENETICS (2012)
Restrictive Physiology is Associated With Poor Outcomes in Children With Hypertrophic Cardiomyopathy
Shiraz A. Maskatia et al.
PEDIATRIC CARDIOLOGY (2012)
Patient-Specific Induced Pluripotent Stem Cells as a Model for Familial Dilated Cardiomyopathy
Ning Sun et al.
SCIENCE TRANSLATIONAL MEDICINE (2012)
Genome-wide Studies of Copy Number Variation and Exome Sequencing Identify Rare Variants in BAG3 as a Cause of Dilated Cardiomyopathy
Nadine Norton et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2011)
Genetic Variation in Titin in Arrhythmogenic Right Ventricular Cardiomyopathy-Overlap Syndromes
Matthew Taylor et al.
CIRCULATION (2011)
Telethonin Deficiency Is Associated With Maladaptation to Biomechanical Stress in the Mammalian Heart
Ralph Knoell et al.
CIRCULATION RESEARCH (2011)
Molecular Genetic and Functional Characterization Implicate Muscle-Restricted Coiled-Coil Gene (MURC) as a Causal Gene for Familial Dilated Cardiomyopathy
Gabriela Rodriguez et al.
CIRCULATION-CARDIOVASCULAR GENETICS (2011)
Desmin-related myopathy
K. Y. van Spaendonck-Zwarts et al.
CLINICAL GENETICS (2011)
HRS/EHRA Expert Consensus Statement on the State of Genetic Testing for the Channelopathies and Cardiomyopathies
Michael J. Ackerman et al.
EUROPACE (2011)
Left ventricular non-compaction revisited: a distinct phenotype with genetic heterogeneity?
Erwin Oechslin et al.
EUROPEAN HEART JOURNAL (2011)
Selective deletion of long but not short Cypher isoforms leads to late-onset dilated cardiomyopathy
Hongqiang Cheng et al.
HUMAN MOLECULAR GENETICS (2011)
Dilated cardiomyopathy-associated BAG3 mutations impair Z-disc assembly and enhance sensitivity to apoptosis in cardiomyocytes
Takuro Arimura et al.
HUMAN MUTATION (2011)
Cardiac Z-disc Signaling Network
Derk Frank et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Molecular Mechanism of the E99K Mutation in Cardiac Actin (ACTC Gene) That Causes Apical Hypertrophy in Man and Mouse
Weihua Song et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Pluripotent stem cell models of cardiac disease and their implication for drug discovery and development
Richard P. Davis et al.
TRENDS IN MOLECULAR MEDICINE (2011)
Mutations in NEXN, a Z-Disc Gene, Are Associated with Hypertrophic Cardiomyopathy
Hu Wang et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2010)
Ca2+/Calmodulin-Dependent Kinase IIδ Causes Heart Failure by Accumulation of p53 in Dilated Cardiomyopathy
Haruhiro Toko et al.
CIRCULATION (2010)
A Common MLP (Muscle LIM Protein) Variant Is Associated With Cardiomyopathy
Ralph Knoell et al.
CIRCULATION RESEARCH (2010)
A ZASP Missense Mutation, S196L, Leads to Cytoskeletal and Electrical Abnormalities in a Mouse Model of Cardiomyopathy
Zhaohui Li et al.
CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY (2010)
The Importance of Genetic Counseling, DNA Diagnostics, and Cardiologic Family Screening in Left Ventricular Noncompaction Cardiomyopathy
Yvonne M. Hoedemaekers et al.
CIRCULATION-CARDIOVASCULAR GENETICS (2010)
Removal of the calpain 3 protease reverses the myopathology in a mouse model for titinopathies
Karine Charton et al.
HUMAN MOLECULAR GENETICS (2010)
Functional muscle analysis of the Tcap knockout mouse
C. D. Markert et al.
HUMAN MOLECULAR GENETICS (2010)
Analysis of the Z-disc genes PDLIM3 and MYPN in Patients with Hypertrophic Cardiomyopathy
Richard D. Bagnall et al.
INTERNATIONAL JOURNAL OF CARDIOLOGY (2010)
MLP: A Stress Sensor Goes Nuclear By Sylvia Gunkel, Jorg Heineke, Denise Hilfiker-Kleiner, Ralph Knoll, J Mol Cell Cardiol. 2009;47(4):423-5.
Katja Gehmlich et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2010)
Investigation of a transgenic mouse model of familial dilated cardiomyopathy
Weihua Song et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2010)
Nebulette Mutations Are Associated With Dilated Cardiomyopathy and Endocardial Fibroelastosis
Enkhsaikhan Purevjav et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2010)
Hearts of surviving MLP-KO mice show transient changes of intracellular calcium handling
Peter Kemecsei et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2010)
The Vinculin-ΔIn20/21 Mouse: Characteristics of a Constitutive, Actin-Binding Deficient Splice Variant of Vinculin
Susanna Marg et al.
PLOS ONE (2010)
Nebulin and N-WASP Cooperate to Cause IGF-1-Induced Sarcomeric Actin Filament Formation
Kazunori Takano et al.
SCIENCE (2010)
Left Ventricular Noncompaction: A New Form of Heart Failure
Jeffrey A. Towbin
Heart Failure Clinics (2010)
Genetics of Restrictive Cardiomyopathy
Srijita Sen-Chowdhry et al.
Heart Failure Clinics (2010)
Impaired binding of ZASP/Cypher with phosphoglucomutase 1 is associated with dilated cardiomyopathy
Takuro Arimura et al.
CARDIOVASCULAR RESEARCH (2009)
Truncation of Titin's Elastic PEVK Region Leads to Cardiomyopathy With Diastolic Dysfunction
Henk L. Granzier et al.
CIRCULATION RESEARCH (2009)
Arrhythmogenic right ventricular cardiomyopathy: an update
Domenico Corrado et al.
HEART (2009)
Cardiac-specific ablation of Cypher leads to a severe form of dilated cardiomyopathy with premature death
Ming Zheng et al.
HUMAN MOLECULAR GENETICS (2009)
Depletion of zebrafish Tcap leads to muscular dystrophy via disrupting sarcomere-membrane interaction, not sarcomere assembly
Ruilin Zhang et al.
HUMAN MOLECULAR GENETICS (2009)
Genetic Evaluation of Cardiomyopathy-A Heart Failure Society of America Practice Guideline
Ray E. Hershberger et al.
JOURNAL OF CARDIAC FAILURE (2009)
Obscurin determines the architecture of the longitudinal sarcoplasmic reticulum
Stephan Lange et al.
JOURNAL OF CELL SCIENCE (2009)
Stress-induced dilated cardiomyopathy in a knock-in mouse model mimicking human titin-based disease
Michael Gramlich et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2009)
MLP: A stress sensor goes nuclear
Sylvia Gunkel et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2009)
Myocyte remodeling in response to hypertrophic stimuli requires nucleocytoplasmic shuttling of muscle LIM protein
Samuel Y. Boateng et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2009)
The vertebrate muscle Z-disc: sarcomere anchor for structure and signalling
Pradeep K. Luther
JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY (2009)
Phenotypic Heterogeneity of Sarcomeric Gene Mutations A Matter of Gain and Loss?
Luisa Mestroni
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2009)
A Class III PDZ Binding Motif in the Myotilin and FATZ Families Binds Enigma Family Proteins: a Common Link for Z-Disc Myopathies
Pernilla von Nandelstadh et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
Muscle Lim Protein Interacts with Cofilin 2 and Regulates F-Actin Dynamics in Cardiac and Skeletal Muscle
Vasiliki Papalouka et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
Integrin-linked kinase is an adaptor with essential functions during mouse development
Anika Lange et al.
NATURE (2009)
Nexilin mutations destabilize cardiac Z-disks and lead to dilated cardiomyopathy
David Hassel et al.
NATURE MEDICINE (2009)
Cytoplasmic Ig-Domain Proteins: Cytoskeletal Regulators with a Role in Human Disease
Carol A. Otey et al.
CELL MOTILITY AND THE CYTOSKELETON (2009)
Bis deficiency results in early lethality with metabolic deterioration and involution of spleen and thymus
Dong-Ye Youn et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2008)
Mutations in sarcomere protein genes in left ventricular noncompaction
Sabine Klaassen et al.
CIRCULATION (2008)
Coding Sequence Mutations Identified in MYH7, TNNT2, SCN5A, CSRP3, LBD3, and TCAP from 313 Patients with Familial or Idiopathic Dilated Cardiomyopathy
Ray E. Hershberger et al.
CTS-CLINICAL AND TRANSLATIONAL SCIENCE (2008)
Genetic determinants of cardiac hypertrophy
Ali J. Marian
CURRENT OPINION IN CARDIOLOGY (2008)
Zebrafish integrin-linked kinase is required in skeletal muscles for strengthening the integrin-ECM adhesion complex
Ruben Postel et al.
DEVELOPMENTAL BIOLOGY (2008)
A missense mutation in desmin tail domain linked to human dilated cardiomyopathy promotes cleavage of the head domain and abolishes its Z-disc localization
Manolis Mavroidis et al.
FASEB JOURNAL (2008)
Idiopathic restrictive cardiomyopathy in children is caused by mutations in cardiac sarcomere protein genes
J. P. Kaski et al.
HEART (2008)
Beyond the sarcomere:: CSRP3 mutations cause hypertrophic cardiomyopathy
Christian Geier et al.
HUMAN MOLECULAR GENETICS (2008)
HDAC4 and PCAF bind to cardiac sarcomeres and play a role in regulating myofilament contractile activity
Mahesh P. Gupta et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Identification of FHL1 as a regulator of skeletal muscle mass: implications for human myopathy
Belinda S. Cowling et al.
JOURNAL OF CELL BIOLOGY (2008)
An FHL1-containing complex within the cardiomyocyte sarcomere mediates hypertrophic biomechanical stress responses in mice
Farah Sheikh et al.
JOURNAL OF CLINICAL INVESTIGATION (2008)
Mice expressing L345P mutant desmin exhibit morphological and functional changes of skeletal and cardiac mitochondria
Anna Kostareva et al.
JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY (2008)
Back to square one: what do we know about the functions of Muscle LIM Protein in the heart?
Katja Gehmlich et al.
JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY (2008)
Left-Dominant Arrhythmogenic Cardiomyopathy
Srijita Sen-Chowdhry et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2008)
MURC, a muscle-restricted coiled-coil protein that modulates the Rho/ROCK pathway, induces cardiac dysfunction and conduction disturbance
Takehiro Ogata et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
Nebulette interacts with filamin C
William B. Holmes et al.
CELL MOTILITY AND THE CYTOSKELETON (2008)
Alpha-cardiac actin mutations produce atrial septal defects
Hans Matsson et al.
HUMAN MOLECULAR GENETICS (2008)
Mutations in the Z-band protein myopalladin gene and idiopathic dilated cardiomyopathy
Laetitia Duboscq-Bidot et al.
CARDIOVASCULAR RESEARCH (2008)
Calsarcin-1 protects against angiotensin-II-induced cardiac hypertrophy
Derk Frank et al.
CIRCULATION (2007)
Cardiac-myocyte-specific excision of the vinculin gene disrupts cellular junctions, causing sudden death or dilated cardiomyopathy
Alice E. Zemljic-Harpf et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
Zeroing in on the role of cypher in striated muscle function, signaling, and human disease
Farah Sheikh et al.
TRENDS IN CARDIOVASCULAR MEDICINE (2007)
Structural analysis of obscurin gene in hypertrophic cardiomyopathy
Takuro Arimura et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Mutation in the alpha-cardiac actin gene associated with apical hypertrophic cardiomyopathy, left ventricular non-compaction, and septal defects
Lorenzo Monserrat et al.
EUROPEAN HEART JOURNAL (2007)
Laminin-α4 and integrin-linked kinase mutations cause human cardiomyopathy via simultaneous defects in cardiomyocytes and endothelial cells
Ralph Knoell et al.
CIRCULATION (2007)
Zaspopathy in a large classic late-onset distal myopathy family
R. Griggs et al.
BRAIN (2007)
Structural analysis of four and half LIM protein-2 in dilated cardiomyopathy
Takuro Arimura et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Mutations in PDLIM3 and MYOZ1 encoding myocyte Z line proteins are infrequently found in idiopathic dilated cardiomyopathy
Anita M. Arola et al.
MOLECULAR GENETICS AND METABOLISM (2007)
Targeted deletion of titin N2B region leads to diastolic dysfunction and cardiac atrophy
Michael H. Radke et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Cardiac dysfunction and heart failure are associated with abnormalities in the subcellular distribution and amounts of oligomeric muscle LIM protein
Samuel Y. Boateng et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2007)
Genetics of dilated cardiomyopathy
Satu Karkkainen et al.
ANNALS OF MEDICINE (2007)
Echocardiographic-determined septal morphology in Z-disc hypertrophic cardiomyopathy
Jeanne L. Theis et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Zebrafish cypher is important for somite formation and heart development
David L. M. van der Meer et al.
DEVELOPMENTAL BIOLOGY (2006)
Titin as a giant scaffold for integrating stress and Src homology domain 3-mediated signaling pathways - The clustering of novel overlap ligand motifs in the elastic PEVK segment
Kan Ma et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Integrin-linked kinase, a novel component of the cardiac mechanical stretch sensor, controls contractility in the zebrafish heart
Garnet Bendig et al.
GENES & DEVELOPMENT (2006)
Loss of FilaminC (FLNc) results in severe defects in myogenesis and myotube structure
I. Dalkilic et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
BAG3 deficiency results in fulminant myopathy and early lethality
Sachiko Homma et al.
AMERICAN JOURNAL OF PATHOLOGY (2006)
Targeted ablation of ILK from the murine heart results in dilated cardiomyopathy and spontaneous heart failure
Donald E. White et al.
GENES & DEVELOPMENT (2006)
Nebulin regulates thin filament length, contractility, and Z-disk structure in vivo
Christian C. Witt et al.
EMBO JOURNAL (2006)
Desmin accumulation restrictive cardiomyopathy and atrioventricular block associated with desmin gene defects
Eloisa Arbustini et al.
EUROPEAN JOURNAL OF HEART FAILURE (2006)
M line-deficient titin causes cardiac lethality through impaired maturation of the sarcomere
Stefanie Weinert et al.
JOURNAL OF CELL BIOLOGY (2006)
Genotype-phenotype relationships involving hypertrophic cardiomyopathy-associated mutations in titin, muscle LIM protein, and telethonin
JM Bos et al.
MOLECULAR GENETICS AND METABOLISM (2006)
Genetic analysis in patients with left ventricular noncompaction and evidence for genetic heterogeneity
YL Xing et al.
MOLECULAR GENETICS AND METABOLISM (2006)
Contemporary definitions and classification of the cardiomyopathies - An American Heart Association Scientific Statement from the Council on Clinical Cardiology, Heart Failure and Transplantation Committee; Quality of Care and Outcomes Research and Functional Genomics and Translational Biology Interdisciplinary Working Groups; And Council on Epidemiology and Prevention
BJ Maron et al.
CIRCULATION (2006)
Identification of a metavinculin missense mutation, R975W, associated with both hypertrophic and dilated cardiomyopathy
VC Vasile et al.
MOLECULAR GENETICS AND METABOLISM (2006)
The sarcomeric Z-disc: a nodal point in signalling and disease
Derk Frank et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2006)
Remodeling of gap junctions and slow conduction in a mouse model of desmin-related cardiomyopathy
JJ Gard et al.
CARDIOVASCULAR RESEARCH (2005)
W4R variant in CSRP3 encoding muscle LIM protein in a patient with hypertrophic cardiomyopathy
B Newman et al.
MOLECULAR GENETICS AND METABOLISM (2005)
Mutations in ZASP define a novel form of muscular dystrophy in humans
D Selcen et al.
ANNALS OF NEUROLOGY (2005)
Attenuation of cardiac remodeling after myocardial infarction by muscle LIM protein-calcineurin signaling at the sarcomeric Z-disc
J Heineke et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Hypertrophy of the heart - A new therapeutic target?
N Frey et al.
CIRCULATION (2004)
Studying cardiac arrhythmias in the mouse - A reasonable model for probing mechanisms?
JM Nerbonne
TRENDS IN CARDIOVASCULAR MEDICINE (2004)
A Cypher/ZASP mutation associated with dilated cardiomyopathy alters the binding affinity to protein kinase C
T Arimura et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
At the crossroads of myocardial signaling - The role of Z-discs in intracellular signaling and cardiac function
WG Pyle et al.
CIRCULATION RESEARCH (2004)
Animal model - Heterozygous inactivation of the vinculin gene predisposes to stress-induced cardiomyopathy
AE Zemljic-Harpf et al.
AMERICAN JOURNAL OF PATHOLOGY (2004)
Tcap gene mutations in hypertrophic cardiomyopathy and dilated cardiomyopathy
T Hayashi et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2004)
Mice lacking calsarcin-1 are sensitized to calcineurin signaling and show accelerated cardiomyopathy in response to pathological biomechanical stress
N Frey et al.
NATURE MEDICINE (2004)
Zyxin interacts with the SH3 domains of the cytoskeletal proteins LIM-nebulette and Lasp-1
B Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Mutations in Cypher/ZASP in patients with dilated cardiomyopathy and left ventricular non-compaction
M Vatta et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2003)
The muscle ankyrin repeat proteins: CARP, ankrd2/Arpp and DARP as a family of titin filament-based stress response molecules
MK Miller et al.
JOURNAL OF MOLECULAR BIOLOGY (2003)
Mutations in the muscle LIM protein and α-actinin-2 genes in dilated cardiomyopathy and endocardial fibroelastosis
B Mohapatra et al.
MOLECULAR GENETICS AND METABOLISM (2003)
Integrin-linked kinase (ILK) is required for polarizing the epiblast, cell adhesion, and controlling actin accumulation
T Sakai et al.
GENES & DEVELOPMENT (2003)
Mutations in the human muscle LIM protein gene in families with hypertrophic cardiomyopathy
C Geier et al.
CIRCULATION (2003)
Characterization and in vivo functional analysis of splice variants of cypher
CQ Huang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Conditional expression of mutant M-line titins results in cardiomyopathy with altered sarcomere structure
M Gotthardt et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Interactions between nebulin-like motifs and thin filament regulatory proteins
O Ogut et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
The cardiac mechanical stretch sensor machinery involves a Z disc complex that is defective in a subset of human dilated cardiomyopathy
R Knöll et al.
CELL (2002)
Interaction of nebulin SH3 domain with titin PEVK and myopalladin: implications for the signaling and assembly role of titin and nebulin
K Ma et al.
FEBS LETTERS (2002)
Calsarcin-3, a novel skeletal muscle-specific member of the calsarcin family, interacts with multiple Z-disc proteins
N Frey et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Cardiac myocyte-specific excision of the β1 integrin gene results in myocardial fibrosis and cardiac failure
SY Shai et al.
CIRCULATION RESEARCH (2002)
Titin mutations as the molecular basis for dilated cardiomyopathy
M Itoh-Satoh et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)
Targeted disruption of nebulette protein expression alters cardiac myofibril assembly and function
CL Moncman et al.
EXPERIMENTAL CELL RESEARCH (2002)
The muscular dystrophy with myositis (mdm) mouse mutation disrupts a skeletal muscle-specific domain of titin
SM Garvey et al.
GENOMICS (2002)
Mutations of TTN, encoding the giant muscle filament titin, cause familial dilated cardiomyopathy
B Gerull et al.
NATURE GENETICS (2002)
Metavinculin mutations alter actin interaction in dilated cardiomyopathy
TM Olson et al.
CIRCULATION (2002)
Ablation of Cypher, a PDZ-LIM domain Z-line protein, causes a severe form of congenital myopathy
Q Zhou et al.
JOURNAL OF CELL BIOLOGY (2001)
Mouse model of desmin-related cardiomyopathy
XJ Wang et al.
CIRCULATION (2001)
Alterations at the intercalated disk associated with the absence of muscle LIM protein
E Ehler et al.
JOURNAL OF CELL BIOLOGY (2001)
Adult mice deficient in actinin-associated LIM-domain protein reveal a developmental pathway for right ventricular cardiomyopathy
M Pashmforoush et al.
NATURE MEDICINE (2001)
Myopalladin, a novel 145-kilodalton sarcomeric protein with multiple roles in Z-disc and I-band protein assemblies
ML Bang et al.
JOURNAL OF CELL BIOLOGY (2001)
Actinin-associated LIM protein-deficient mice maintain normal development and structure of skeletal muscle
K Jo et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
FATZ, a filamin-, actinin-, and telethonin-binding protein of the Z-disc of skeletal muscle
G Faulkner et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Calsarcins, a novel family of sarcomeric calcineurin-binding proteins
N Frey et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Characterization of the human nebulette gene: a polymorphism in an actin-binding motif is associated with nonfamilial idiopathic dilated cardiomyopathy
T Arimura et al.
HUMAN GENETICS (2000)
FHL2 (SLIM3) is not essential for cardiac development and function
PH Chu et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
Decreased expression of the cardiac LIM domain protein MLP in chronic human heart failure
O Zolk et al.
CIRCULATION (2000)
Oracle, a novel PDZ-LIM domain protein expressed in heart and skeletal muscle
R Passier et al.
MECHANISMS OF DEVELOPMENT (2000)
Inherited and de novo mutations in the cardiac actin gene cause hypertrophic cardiomyopathy
TM Olson et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2000)