4.4 Article

Alzheimer's Disease: Epidemiology and Clinical Progression

Related references

Note: Only part of the references are listed.
Review Clinical Neurology

Microglia and immunotherapy in Alzheimer's disease

Qingqing Li et al.

Summary: Microglia play a dual role in Alzheimer's disease by causing neuronal damage and AD onset, while also protecting the central nervous system by engulfing Aβ. Understanding the role of microglia is essential for the prevention and treatment of AD.

ACTA NEUROLOGICA SCANDINAVICA (2022)

Article Clinical Neurology

Estimating Progression Rates Across the Spectrum of Alzheimer's Disease for Amyloid-Positive Individuals Using National Alzheimer's Coordinating Center Data

Michele Potashman et al.

Summary: This study provides transition probabilities of individuals with amyloid-beta pathology across the disease continuum. Results show the probabilities of transitioning between different stages of the disease, which can be used to assess the impact of treatment on expected transitions.

NEUROLOGY AND THERAPY (2021)

Review Geriatrics & Gerontology

Prevalence of mild cognitive impairment in community-dwelling Chinese populations aged over 55years: a meta-analysis and systematic review

Yuan Lu et al.

Summary: This study aimed to synthesize the prevalence results of MCI and aMCI in community-dwelling populations in China. The findings showed that MCI prevalence increased with age, with aMCI accounting for 66.5% of the cases. Women, rural residents, and those with low education levels had higher MCI prevalence rates.

BMC GERIATRICS (2021)

Article Clinical Neurology

Clinical diagnosis of Alzheimer's disease: recommendations of the International Working Group

Bruno Dubois et al.

Summary: The use of biomarkers in the diagnosis of Alzheimer's disease has limitations and should be used cautiously in a clinical setting, restricted to individuals with specific phenotypes and positive biomarkers. Biomarker-positive cognitively unimpaired individuals should be considered at-risk for progression to Alzheimer's disease.

LANCET NEUROLOGY (2021)

Review Behavioral Sciences

Blood biomarkers for the diagnosis of amnestic mild cognitive impairment and Alzheimer's disease: A systematic review and meta-analysis

Yi Qu et al.

Summary: Blood-based biomarkers of AD pathology show significant changes between AD, aMCI, and control groups, indicating their strong validity in identifying AD and aMCI, and providing a new prospect for early diagnosis and monitoring of AD.

NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2021)

Article Clinical Neurology

2021 Alzheimer's disease facts and figures

[Anonymous]

Summary: Alzheimer's disease has a significant impact on individuals and society as a whole, with a large number of patients in the United States and a potential for continued growth in the future. The value of unpaid caregivers has increased despite a decline in their numbers, and healthcare costs are on the rise. Racial and ethnic disparities in healthcare persist, highlighting the need for greater diversity in dementia care workforce and clinical trials.

ALZHEIMERS & DEMENTIA (2021)

Article Clinical Neurology

The prevalence of Alzheimer's disease in the Chinese Han population: a meta-analysis

Xingxing Zhao et al.

NEUROLOGICAL RESEARCH (2020)

Article Geriatrics & Gerontology

Prevalence of Alzheimer's Disease and Parkinson's Disease in China: An Updated Systematical Analysis

Lei Cui et al.

FRONTIERS IN AGING NEUROSCIENCE (2020)

Article Medicine, General & Internal

The Alzheimer's Disease Clinical Spectrum Diagnosis and Management

Alireza Atri

MEDICAL CLINICS OF NORTH AMERICA (2019)

Article Cell Biology

Cortisol and IgA are Involved in the Progression of Alzheimer's Disease. A Pilot Study

Jose Enrique de la Rubia Orti et al.

CELLULAR AND MOLECULAR NEUROBIOLOGY (2019)

Article Peripheral Vascular Disease

Blood Pressure Variability and Progression of Clinical Alzheimer Disease

Rianne A. A. de Heus et al.

HYPERTENSION (2019)

Review Geriatrics & Gerontology

Role of Microglial Cells in Alzheimer's Disease Tau Propagation

Ena Spanic et al.

FRONTIERS IN AGING NEUROSCIENCE (2019)

Review Cell Biology

Neuroinflammation in mild cognitive impairment and Alzheimer's disease: A meta-analysis

Steven Bradburn et al.

AGEING RESEARCH REVIEWS (2019)

Article Gerontology

Performance on Neuropsychological Assessment and Progression to Dementia: A Meta-Analysis

Catherine E. Prado et al.

PSYCHOLOGY AND AGING (2019)

Review Clinical Neurology

The incidence of mild cognitive impairment: A systematic review and data synthesis

Cai Gillis et al.

ALZHEIMER'S & DEMENTIA: DIAGNOSIS, ASSESSMENT & DISEASE MONITORING (2019)

Article Clinical Neurology

Baseline Amnestic Severity Predicts Progression From Amnestic Mild Cognitive Impairment to Alzheimer Disease Dementia at 3 Years

Nicholas I. Bradfield et al.

ALZHEIMER DISEASE & ASSOCIATED DISORDERS (2018)

Article Clinical Neurology

Forecasting the prevalence of preclinical and clinical Alzheimer's disease in the United States

Ron Brookmeyer et al.

ALZHEIMERS & DEMENTIA (2018)

Review Clinical Neurology

NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease

Clifford R. Jack et al.

ALZHEIMERS & DEMENTIA (2018)

Article Neurosciences

Progression of Alzheimer's Disease: A Longitudinal Study in Norwegian Memory Clinics

Rannveig Sakshaug Eldholm et al.

JOURNAL OF ALZHEIMERS DISEASE (2018)

Article Geriatrics & Gerontology

Using Base Rate of Low Scores to Identify Progression from Amnestic Mild Cognitive Impairment to Alzheimer's Disease

Javier Oltra-Cucarella et al.

JOURNAL OF THE AMERICAN GERIATRICS SOCIETY (2018)

Review Health Care Sciences & Services

Epidemiology, associated burden, and current clinical practice for the diagnosis and management of Alzheimer's disease in Japan

William Montgomery et al.

CLINICOECONOMICS AND OUTCOMES RESEARCH (2018)

Article Clinical Neurology

Trends of mortality from Alzheimer's disease in the European Union, 1994-2013

H. Niu et al.

EUROPEAN JOURNAL OF NEUROLOGY (2017)

Review Neurosciences

A Systematic Review of Longitudinal Studies Which Measure Alzheimer's Disease Biomarkers

Emma Lawrence et al.

JOURNAL OF ALZHEIMERS DISEASE (2017)

Review Medicine, General & Internal

Mild cognitive impairment and progression to dementia of Alzheimer's disease

Ana Beatriz Quintes Steiner et al.

REVISTA DA ASSOCIACAO MEDICA BRASILEIRA (2017)

Review Multidisciplinary Sciences

Comorbidity and progression of late onset Alzheimer's disease: A systematic review

Miriam L. Haaksma et al.

PLOS ONE (2017)

Article Clinical Neurology

Both Financial and Cognitive Decline Predict Clinical Progression in MCI

Adam Gerstenecker et al.

ALZHEIMER DISEASE & ASSOCIATED DISORDERS (2016)

Article Clinical Neurology

Predicting the Rate of Cognitive Decline in Alzheimer Disease: Data From the ICTUS Study

Marco Canevelli et al.

ALZHEIMER DISEASE & ASSOCIATED DISORDERS (2016)

Article Clinical Neurology

Predicting the progression of Alzheimer's disease dementia: A multidomain health policy model

Colin Green et al.

Alzheimers & Dementia (2016)

Review Clinical Neurology

The Prevalence and Incidence of Dementia Due to Alzheimer's Disease: a Systematic Review and Meta-Analysis

Kirsten M. Fiest et al.

CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES (2016)

Review Medicine, General & Internal

Alzheimer's disease

Philip Scheltens et al.

LANCET (2016)

Article Psychiatry

Risk Factors for Progression of Alzheimer Disease in a Canadian Population: The Canadian Outcomes Study in Dementia (COSID)

Nathan Herrmann et al.

CANADIAN JOURNAL OF PSYCHIATRY-REVUE CANADIENNE DE PSYCHIATRIE (2015)

Article Geriatrics & Gerontology

Impact of cognitive reserve on the progression of mild cognitive impairment to Alzheimer's disease in Japan

Akira Osone et al.

GERIATRICS & GERONTOLOGY INTERNATIONAL (2015)

Article Medicine, General & Internal

Update on the core and developing cerebrospinal fluid biomarkers for Alzheimer disease

Mirjana Babic et al.

CROATIAN MEDICAL JOURNAL (2014)

Article Geriatrics & Gerontology

Normal Cognitive Aging

Caroline N. Harada et al.

CLINICS IN GERIATRIC MEDICINE (2013)