Model-based cost-effectiveness analysis of oral antivirals against SARS-CoV-2 in Korea

Letter Medicine, General & Internal

Characteristics and Outcomes of Hospitalized Patients in South Africa During the COVID-19 Omicron Wave Compared With Previous Waves

Caroline Maslo et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2022)

Article Infectious Diseases

Decreased severity of disease during the first global omicron variant covid-19 outbreak in a large hospital in tshwane, south africa

F. Abdullah et al.

Summary: This study analyzed the clinical data of COVID-19 patients admitted to a hospital in Tshwane during the Omicron wave, and found that the severity of the disease was decreased compared to previous waves, with lower death rates and ICU admissions.

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2022)

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Article Multidisciplinary Sciences

Increased risk of SARS-CoV-2 reinfection associated with emergence of Omicron in South Africa

Juliet R. C. Pulliam et al.

Summary: This study provides two methods for monitoring reinfection trends in routine surveillance data. The results suggest immune evasion by the Omicron variant in previously infected individuals in South Africa, and there has been an increase in the risk of having a third infection since mid-November 2021.

SCIENCE (2022)

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Article Infectious Diseases

Effectiveness of Oseltamivir in reducing 30-day readmissions and mortality among patients with severe seasonal influenza in Australian hospitalized patients

Yogesh Sharma et al.

Summary: The study showed that early administration of Oseltamivir in adult hospitalized influenza patients can reduce 30-day readmissions and the composite outcome of 30-day readmissions and mortality.

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2021)

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Article Immunology

Cost-effectiveness of Remdesivir and Dexamethasone for COVID-19 Treatment in South Africa

Youngji Jo et al.

Summary: The study suggests that in South Africa, using remdesivir for nonventilated patients and dexamethasone for ventilated patients may be more cost-effective than standard care, saving lives and costs. Further efforts to improve recovery time with remdesivir and dexamethasone in ICUs could have potential benefits in terms of saving lives and costs.

OPEN FORUM INFECTIOUS DISEASES (2021)

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News Item Medicine, General & Internal

Covid-19: Pfizer's paxlovid is 89% effective in patients at risk of serious illness, company reports

Elisabeth Mahase

BMJ-BRITISH MEDICAL JOURNAL (2021)

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Article Pediatrics

Influenza Antiviral Treatment and Length of Stay

Angela P. Campbell et al.

Summary: This study evaluated the impact of antiviral treatment on hospital length of stay among children hospitalized with confirmed influenza, finding that early antiviral treatment was associated with significantly shorter hospitalizations. These results support the CDC recommendations for prompt empiric antiviral treatment in hospitalized patients with suspected or confirmed influenza.

PEDIATRICS (2021)

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Article Multidisciplinary Sciences

Variable effects of underlying diseases on the prognosis of patients with COVID-19

Yong Jun Choi et al.

Summary: This study found that patients with COVID-19 who have underlying chronic diseases have a poorer prognosis. Specific underlying diseases significantly increase treatment costs or prolong hospital stays, and even increase the risk of death.

PLOS ONE (2021)

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Article Medicine, General & Internal

Association of Remdesivir Treatment With Survival and Length of Hospital Stay Among US Veterans Hospitalized With COVID-19

Michael E. Ohl et al.

Summary: This study examined the association between remdesivir treatment and survival as well as length of hospital stay among COVID-19 patients. The results showed that remdesivir treatment was not associated with improved survival but was linked to longer hospital stays.

JAMA NETWORK OPEN (2021)

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Article Medicine, General & Internal

Prediction of COVID-19-related Mortality and 30-Day and 60-Day Survival Probabilities Using a Nomogram

Hui Jeong Moon et al.

Summary: This study investigated the factors associated with mortality in COVID-19 patients and developed a nomogram for predicting mortality accurately. Differences in age, gender, underlying diseases, and symptoms were found to be closely related to survival and mortality rates in COVID-19 patients.

JOURNAL OF KOREAN MEDICAL SCIENCE (2021)

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Editorial Material Medicine, General & Internal