Journal
MATERIALS TODAY CHEMISTRY
Volume 23, Issue -, Pages -Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.mtchem.2021.100703
Keywords
Carbon dots (CDs); Tetraphenylethylene (TPE); Aggregation-induced effect (AIE); Bioimaging
Funding
- Na-tional Natural Science Foundation of China [21776218, 52173279]
- Natural Science Foundation of Hunan Province [2020JJ4303]
- Scientific Research Fund of Hunan Provincial Education Department [20A181]
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The synthesized CD-g-poly(TPE-block-NIPAM) nano-particles exhibit different fluorescence behaviors in THF and water, making them potential fluorescent tracers for living cells.
Carbon dots (CDs) grafted with block polymer of tetraphenylethylene (TPE) and N-isopropylacrylamide (CD-g-poly(TPE-block-NIPAM)) were synthesized, which are aggregation-induced emission (AIE) nano-particles. The CD-g-poly(TPE-block-NIPAM) exhibited different fluorescence behaviors in tetrahydrofuran (THF) and water. In THF, the CD-g-poly(TPE-block-NIPAM) could fluoresce, but only from CDs, and the TPE block showed no fluorescence. The fluorescence of CDs was quenched ,and the TPE block showed AIE, when the CD-g-poly(TPE-block-NIPAM) were dispersed in water. The CD-g-poly(TPE-block-NIPAM) showed no cytotoxicity, which could be easily internalized by human breast cancer cells and human embryonic kidney cells with high fluorescence, and they can be used as fluorescent tracers for living cells. (c) 2021 Elsevier Ltd. All rights reserved.
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