A rare case of penile schwannomatosis presenting with painful nocturnal penile tumescence

Background: Penile schwannoma is a rare tumor. They commonly present as an asymptomatic, painless and slow growing mass. Other presentations include sexual dysfunction, most commonly dyspareunia, followed by erectile dysfunction, abnormal penile curvature or pain with ejaculation. Case presentation: A 26-year-old male presented atypically with painful nocturnal penile tumescence, along with multiple nodules over the dorsal penis. Excision of multiple penile tumors under general anaesthesia was performed and histopathologic examination revealed benign schwannoma. Conclusion: Our hypothesis is that the schwannoma lies along the axis of the dorsal penile nerve, and compression of this nerve occurs during his erection causing pain. However, there are limited presentations of painful erections in penile schwannomas, and we hope that future studies can help confirm this theory.

Automated summary

This article presents a rare case of penile schwannoma, in which the patient experienced painful nocturnal penile tumescence and had multiple nodules. Surgical excision confirmed the diagnosis of benign schwannoma. The authors propose a possible etiology and suggest further research to validate their hypothesis.