4.7 Editorial Material

Amplification of actin polymerization forces

Journal

JOURNAL OF CELL BIOLOGY
Volume 212, Issue 7, Pages 763-766

Publisher

ROCKEFELLER UNIV PRESS
DOI: 10.1083/jcb.201512019

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Funding

  1. European Molecular Biology Laboratory
  2. Center for Modelling and Simulation in the Biosciences
  3. European Commission under FP7 grant [258068]

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The actin cytoskeleton drives many essential processes in vivo, using molecular motors and actin assembly as force generators. We discuss here the propagation of forces caused by actin polymerization, highlighting simple configurations where the force developed by the network can exceed the sum of the polymerization forces from all filaments.

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