4.7 Review

A Review on Flexible Electrochemical Biosensors to Monitor Alcohol in Sweat

Journal

BIOSENSORS-BASEL
Volume 12, Issue 4, Pages -

Publisher

MDPI
DOI: 10.3390/bios12040252

Keywords

road accidents; alcohol; biomarkers; biosensor; target analyte; biomimetic

Funding

  1. Portuguese Foundation for Science and Technology (FCT) [POCI-01-0247-FEDER-047012]
  2. FEDER funds by means of Portugal 2020 Competitive Factors Operational Program (POCI) [POCI-01-0247-FEDER-047012]
  3. Portuguese Government (OE) [POCI-01-0247-FEDER-047012]
  4. plurianual 2020-2023 Project [UIDB/00264/2020]
  5. 2C2T [UID/CTM/00264/2020]

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The development of efficient and cost-effective healthcare products, such as textile biosensors, has been encouraged by the focus on improving the quality of human life. These biosensors have the potential to provide medical diagnosis anytime and anywhere, and can also aid in improving road safety, especially in the case of alcohol-related accidents.
The continued focus on improving the quality of human life has encouraged the development of increasingly efficient, durable, and cost-effective products in healthcare. Over the last decade, there has been substantial development in the field of technical and interactive textiles that combine expertise in electronics, biology, chemistry, and physics. Most recently, the creation of textile biosensors capable of quantifying biometric data in biological fluids is being studied, to detect a specific disease or the physical condition of an individual. The ultimate goal is to provide access to medical diagnosis anytime and anywhere. Presently, alcohol is considered the most commonly used addictive substance worldwide, being one of the main causes of death in road accidents. Thus, it is important to think of solutions capable of minimizing this public health problem. Alcohol biosensors constitute an excellent tool to aid at improving road safety. Hence, this review explores concepts about alcohol biomarkers, the composition of human sweat and the correlation between alcohol and blood. Different components and requirements of a biosensor are reviewed, along with the electrochemical techniques to evaluate its performance, in addition to construction techniques of textile-based biosensors. Special attention is given to the determination of biomarkers that must be low cost and fast, so the use of biomimetic materials to recognize and detect the target analyte is turning into an attractive option to improve electrochemical behavior.

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