4.6 Review

Probiotics Interact With Lipids Metabolism and Affect Gut Health

Related references

Note: Only part of the references are listed.
Article Microbiology

Probiotics and their Metabolites Reduce Oxidative Stress in Middle-Aged Mice

Wen-Yang Lin et al.

Summary: Probiotics such as Lactobacillus and Bifidobacterium and their fermented metabolites exhibit antioxidative activities, regulate oxidative stress, and protect cells. Experiments show that these strains and their metabolites can elevate antioxidative levels in aging mice and have positive effects on the gut microbiota.

CURRENT MICROBIOLOGY (2022)

Article Medicine, Research & Experimental

Pediococcus pentosaceus CECT 8330 protects DSS-induced colitis and regulates the intestinal microbiota and immune responses in mice

Fang Dong et al.

Summary: The study demonstrated that P. pentosaceus CECT 8330 treatment protected against DSS-induced colitis in mice by reducing weight loss, disease activity index, histological damage, and colon length shortening. It also modulated the immunological profiles and gut microbiota composition and function, suggesting its potential as a promising probiotic for alleviating intestinal inflammation.

JOURNAL OF TRANSLATIONAL MEDICINE (2022)

Article Microbiology

Probiotics Exhibit Strain-Specific Protective Effects in T84 Cells Challenged With Clostridioides difficile-Infected Fecal Water

Mohd Baasir Gaisawat et al.

Summary: Clostridioides difficile infection (CDI) is associated with intestinal injury and mucosal barrier dysfunction, leading to an inflammatory response. Probiotics have the ability to modulate the immune response and protect against CDI-mediated inflammation in the gut. This study evaluated the effectiveness of different probiotic strains in reducing pro-inflammatory cytokine production and improving cell viability in CDI-exposed cells.

FRONTIERS IN MICROBIOLOGY (2022)

Article Immunology

Curcumin alleviates lipopolysaccharides-induced inflammation and apoptosis in vascular smooth muscle cells via inhibition of the NF-kappa B and JNK signaling pathways

Haohang Ruan et al.

Summary: Curcumin can alleviate inflammatory damage in vascular smooth muscle cells induced by LPS by inhibiting the release of inflammatory cytokines, increasing cell viability, and reducing apoptosis. Additionally, curcumin increases the expression of TLR4 and acts through blocking NF-κB and JNK signaling pathways.

INFLAMMOPHARMACOLOGY (2022)

Article Environmental Sciences

Hereditary, environmental, and dietary risk factors of colorectal cancer: a case-control study in the Algerian East

Samira Negrichi et al.

Summary: Colorectal carcinoma (CRC) is the second most common cancer diagnosed in Algeria, with an increasing incidence and mortality rate. Factors such as high education level, family history of cancer, occupational exposures, obesity, alcohol consumption, and dietary factors were found to be associated with CRC risk in this study. Public health campaigns to raise awareness about CRC and promote healthy dietary choices may help in prevention.

ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH (2021)

Article Biochemistry & Molecular Biology

3 PUFAs inhibited hepatic ER stress induced by feeding of a high-saturated fat diet accompanied by the expression LOX-1

Junlin Zhang et al.

Summary: Excessive consumption of saturated fat leads to NAFLD, which can be alleviated by supplementation of n-3 PUFAs. The study demonstrated the crucial role of LOX-1 in HFD-induced ER stress, with potential implications for treating or preventing NAFLD.

JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2021)

Review Immunology

Cancer Focus Lipid metabolism and cancer

Xueli Bian et al.

Summary: Dysregulation of lipid metabolism plays a significant role in cancer progression, and understanding the regulation and disruption of lipid metabolism in cancer cells have led to promising clinical approaches in cancer therapy.

JOURNAL OF EXPERIMENTAL MEDICINE (2021)

Review Neurosciences

Cholesterol Metabolism in Neurodegenerative Diseases: Molecular Mechanisms and Therapeutic Targets

Lijun Dai et al.

Summary: Cholesterol is essential for cell membrane integrity and plays critical roles in physiological processes, particularly in the brain where its metabolism is closely linked to neurodegenerative diseases. Statins, a class of lipid-lowering drugs, have been reported to have a positive impact on neurodegenerative diseases, but the specific mechanisms are still under investigation.

MOLECULAR NEUROBIOLOGY (2021)

Review Biochemistry & Molecular Biology

Effects of Arachidonic Acid Metabolites on Cardiovascular Health and Disease

Yan Zhou et al.

Summary: Arachidonic acid metabolism plays a crucial role in cardiovascular health and disease by modulating vascular tone and cardiovascular complications through different actions on receptors and vascular beds, indicating potential therapeutic implications.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Article Microbiology

Prevention and Alleviation of Dextran Sulfate Sodium Salt-Induced Inflammatory Bowel Disease in Mice With Bacillus subtilis-Fermented Milk via Inhibition of the Inflammatory Responses and Regulation of the Intestinal Flora

Xuan Zhang et al.

Summary: The therapeutic effect of B. subtilis-fermented milk on DSS-induced IBD in mice was evaluated in this study. Results showed a decrease in disease activity index, attenuation of intestinal mucosa injury, reduction of inflammatory response, induction of intestinal stem cell proliferation, and promotion of mucosal barrier reconstruction after oral administration of B. subtilis. Additionally, B. subtilis could rebalance the gut microbiota, increasing the abundance of beneficial bacteria while decreasing harmful bacteria.

FRONTIERS IN MICROBIOLOGY (2021)

Article Biochemistry & Molecular Biology

DHA induces Jurkat T-cell arrest in G2/M phase of cell cycle and modulates the plasma membrane expression of TRPC3/6 channels

Hamza Saidi et al.

Summary: DHA modulates calcium signaling and cell cycle progression in human T-cells by regulating TRPC3 and TRPC6 channels, resulting in inhibition of cell cycle progression and proliferation.

BIOCHIMIE (2021)

Article Biochemistry & Molecular Biology

Strain-Specific Effects of Bifidobacterium longum on Hypercholesterolemic Rats and Potential Mechanisms

Jinchi Jiang et al.

Summary: This study found that different strains of B. longum have strain-specific effects in alleviating hypercholesterolemia, mainly due to differences in bile salt deconjugation ability, cholesterol assimilation ability, expressions of key genes involved in cholesterol metabolism, and alterations of gut microbiota.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Review Medicine, General & Internal

Effects of aerobic exercise on TC, HDL-C, LDL-C and TG in patients with hyperlipidemia A protocol of systematic review and meta-analysis

Shaoping Zhao et al.

Summary: Changes in dietary structure can lead to increased blood lipids, which in turn can increase the risk of cardiovascular and cerebrovascular diseases.

MEDICINE (2021)

Review Geriatrics & Gerontology

Neurodegenerative Diseases and Cholesterol: Seeing the Field Through the Players

Frank W. Pfrieger

Summary: This article introduces the workforce studying neurodegeneration and cholesterol using TeamTree analysis, revealing the history, dynamics, and key players in the field. The team-centered view exposes key players in the field of biomedical research.

FRONTIERS IN AGING NEUROSCIENCE (2021)

Review Physiology

Bioactive Compounds in Edible Oils and Their Role in Oxidative Stress and Inflammation

Alessandra Mazzocchi et al.

Summary: Edible fats and oils, particularly those containing polyunsaturated fatty acids and phenolic compounds, may have anti-inflammatory, antioxidant, and immunomodulatory effects, contributing to the prevention of chronic diseases. Additionally, a high content of monounsaturated fatty acids in edible oils may improve lipid profiles and reduce damage caused by oxidized lipoproteins and free radicals.

FRONTIERS IN PHYSIOLOGY (2021)

Article Ophthalmology

Lactobacillus sakei Pro-Bio65 Reduces TNF-α Expression and Upregulates GSH Content and Antioxidant Enzymatic Activities in Human Conjunctival Cells

Roberto Iorio et al.

Summary: The study investigates the regulatory effects of Lactobacillus sakei pro-Bio65 lysate on human conjunctival epithelial cells, showing that it does not affect cell proliferation but induces low levels of intracellular ROS and changes in mitochondrial membrane potential. Additionally, it upregulates antioxidant defense efficiency and reduces TNF-alpha expression, suggesting the potential application of L.SK paraprobiotic in promoting eye health and preventing oxidative stress-related conditions.

TRANSLATIONAL VISION SCIENCE & TECHNOLOGY (2021)

Review Cell Biology

Roles of Lipid Peroxidation-Derived Electrophiles in Pathogenesis of Colonic Inflammation and Colon Cancer

Lei Lei et al.

Summary: This review discusses the common feature of redox stress in gut disorders and its impact on the development of inflammatory bowel disease (IBD) and colorectal cancer (CRC), emphasizing the critical role of lipid-derived electrophiles in the pathogenesis of these diseases.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)

Article Biochemistry & Molecular Biology

Anti-Neuroinflammatory and Anti-Inflammatory Activities of Phenylheptatriyne Isolated from the Flowers of Coreopsis lanceolata L. via NF-κB Inhibition and HO-1 Expression in BV2 and RAW264.7 Cells

Hwan Lee et al.

Summary: The study identified phenylheptatriyne from Coreopsis lanceolata as an anti-neuroinflammatory and anti-inflammatory compound, showing inhibition of inflammatory cytokine secretion and nitric oxide production. This compound may have therapeutic potential for neuroinflammation-related diseases.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Review Biochemistry & Molecular Biology

Dietary Habits and Gut Microbiota in Healthy Adults: Focusing on the Right Diet. A Systematic Review

Giulia Gibiino et al.

Summary: Diet plays a crucial role in influencing our intestinal microbiota and ecosystem balance, but a clearly defined dietary regime to ensure its health is still lacking. The Mediterranean diet may potentially have significant benefits for our health through direct interaction with our microbiota.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Article Nutrition & Dietetics

Implications of SCFAs on the Parameters of the Lipid and Hepatic Profile in Pregnant Women

Maciej Zietek et al.

Summary: The study analyzed the correlation of SCFAs with lipid and hepatic metabolism during pregnancy in relation to the body weight of pregnant women. Significant differences in concentrations of certain SCFAs were found in overweight and obese women compared to the control group, with some SCFAs being associated with hepatic lipid metabolism and CRP concentrations.

NUTRIENTS (2021)

Article Nutrition & Dietetics

Krill Oil Treatment Increases Distinct PUFAs and Oxylipins in Adipose Tissue and Liver and Attenuates Obesity-Associated Inflammation via Direct and Indirect Mechanisms

Eveline Gart et al.

Summary: Long-term treatment with krill oil leads to increased concentrations of anti-inflammatory compounds in white adipose tissue and liver, resulting in beneficial effects on metabolism and inflammation at the tissue level.

NUTRIENTS (2021)

Article Multidisciplinary Sciences

Rhizospheric Lactobacillus plantarum (Lactiplantibacillus plantarum) strains exhibit bile salt hydrolysis, hypocholestrolemic and probiotic capabilities in vitro

Neelja Singhal et al.

Summary: The study reported the isolation and evaluation of probiotic capabilities of Lactiplantibacillus plantarum strains from rhizospheric soil, which showed strong hypocholesterolemic potential and resistance to various environmental stresses, as well as exhibited resistance to acidic environment and multiple antibiotics. Further investigation is recommended for its potential as a potent probiotic with hypocholesterolemic biotherapeutic benefits, and the potential of exploring rhizosphere as a niche for isolating microorganisms with probiotic potential.

SCIENTIFIC REPORTS (2021)

Article Biochemistry & Molecular Biology

The lipid peroxidation product EKODE exacerbates colonic inflammation and colon tumorigenesis

Lei Lei et al.

Summary: Oxidative stress is a significant contributor to the pathogenesis of colorectal cancer, with the lipid peroxidation product EKODE playing a crucial role in colonic inflammation and colon tumorigenesis.

REDOX BIOLOGY (2021)

Article Integrative & Complementary Medicine

The beneficial effects of the composite probiotics from camel milk on glucose and lipid metabolism, liver and renal function and gut microbiota in db/db mice

Tabusi Manaer et al.

Summary: CPCM significantly improved glucose and lipid metabolism, liver and kidney function, and islet protection in db/db mice. It also modulated intestinal flora, suggesting potential beneficial effects for patients with T2DM.

BMC COMPLEMENTARY MEDICINE AND THERAPIES (2021)

Article Nanoscience & Nanotechnology

Mitigation of Obesity-Related Systemic Low-Grade Inflammation and Gut Microbial Dysbiosis in Mice with Nanosilver Supplement

Jianbo Jia et al.

Summary: The study found that supplementation with nanosilver can alleviate systemic low-grade inflammation in obese mice, increase the diversity of gut microbial communities, and significantly impact the relative abundance of certain beneficial bacterial genera.

ACS APPLIED BIO MATERIALS (2021)

Review Endocrinology & Metabolism

The effect of probiotics on lipid profile & anthropometric indices in diabetic nephropathy; a systematic review and meta-analysis of clinical trials

Amir Reza Moravejolahkami et al.

Summary: This study aimed to explore the efficacy of probiotics in Diabetic Nephropathy (DN) patients through a reanalysis of related literature. While a marginal reduction in lipid biomarkers was observed, anthropometric indices showed a non-significant increase. Limited evidence was found to support the efficacy of probiotics in modulating lipid profile and anthropometric indices in DN patients.

JOURNAL OF DIABETES AND METABOLIC DISORDERS (2021)

Article Biochemistry & Molecular Biology

Diverse conditions contribute to the cholesterol-lowering ability of different Lactobacillus plantarum strains

Guangqiang Wang et al.

Summary: Different strains of Lactobacillus plantarum exhibit varying abilities in lowering cholesterol, with factors such as ox bile and bile salt hydrolase influencing their effectiveness in a strain-specific manner. Further research is needed to elucidate the exact mechanisms by which different strains reduce cholesterol levels.

FOOD & FUNCTION (2021)

Article Plant Sciences

Kazak faecal microbiota transplantation induces short-chain fatty acids that promote glucagon-like peptide-1 secretion by regulating gut microbiota in db/db mice

Xue Han et al.

Summary: Faecal microbiota transplantation (FMT) from Kazak individuals with normal glucose tolerance (KNGT) can improve glycolipid disorders in type 2 diabetes mellitus db/db mice by changing the bacterial composition responsible for producing short-chain fatty acids (SCFAs) and activating the G protein-coupled receptor 43 (GPR43)/glucagon-like peptide-1 (GLP-1) pathway.

PHARMACEUTICAL BIOLOGY (2021)

Article Gastroenterology & Hepatology

Association of Pre-diagnostic Antibody Responses to Escherichia coli and Bacteroides fragilis Toxin Proteins with Colorectal Cancer in a European Cohort

Julia Butt et al.

Summary: The study found that sero-positivity to E. coli and ETBF was associated with the development of CRC, with dual infection of these bacterial species potentially contributing to colorectal carcinogenesis. These findings call for further exploration in larger prospective studies and within different population groups.

GUT MICROBES (2021)

Review Gastroenterology & Hepatology

Non-alcoholic fatty liver disease in inflammatory bowel disease patients

Katerina Karaivazoglou et al.

EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY (2020)

Article Biochemistry & Molecular Biology

Acetate and Butyrate Improve β-cell Metabolism and Mitochondrial Respiration under Oxidative Stress

Shuxian Hu et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Review Cell Biology

Mechanisms and regulation of cholesterol homeostasis

Jie Luo et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2020)

Article Nutrition & Dietetics

Effect of zymomonas mobilis probiotic on cholesterol and its lipoprotein fractions and the intestinal regulation

Andreza Tallyne de Aguiar Silva et al.

CLINICAL NUTRITION (2020)

Article Agriculture, Multidisciplinary

Effects of Linoleic Acid-Rich Diet on Plasma Profiles of Eicosanoids and Development of Colitis in Il-10-/- Mice

Minhao Xie et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2020)

Review Nutrition & Dietetics

Gut Microbiota in Hypertension and Atherosclerosis: A Review

Barbara J. H. Verhaar et al.

NUTRIENTS (2020)

Article Food Science & Technology

The intervention effects of Lactobacillus casei LC2W on Escherichia coli O157:H7-induced mouse colitis

Guangqiang Wang et al.

FOOD SCIENCE AND HUMAN WELLNESS (2020)

Review Gastroenterology & Hepatology

Gut bacteria signaling to mitochondria in intestinal inflammation and cancer

Dakota N. Jackson et al.

GUT MICROBES (2020)

Review Biochemistry & Molecular Biology

Role of Ox-LDL and LOX-1 in Atherogenesis

Ajoe John Kattoor et al.

CURRENT MEDICINAL CHEMISTRY (2019)

Meeting Abstract Gastroenterology & Hepatology

DETECTION OF BACTERIAL ENTERIC INFECTION IMPACTS MANAGEMENT OF OUTPATIENTS WITH FLARES OF INFLAMMATORY BOWEL DISEASE

Soonwook Hong et al.

INFLAMMATORY BOWEL DISEASES (2019)

Review Biochemistry & Molecular Biology

Lifestyle and dietary environmental factors in colorectal cancer susceptibility

Neil Murphy et al.

MOLECULAR ASPECTS OF MEDICINE (2019)

Review Endocrinology & Metabolism

Oxysterols and Gastrointestinal Cancers Around the Clock

Ursa Kovac et al.

FRONTIERS IN ENDOCRINOLOGY (2019)

Article Biochemistry & Molecular Biology

Novel COX-2 products of n-3 polyunsaturated fatty acid-ethanolamine-conjugates identified in RAW264.7 macrophages[S]

Ian de Bus et al.

JOURNAL OF LIPID RESEARCH (2019)

Review Nutrition & Dietetics

The association of short-chain fatty acids and leptin metabolism: a systematic review

Fernanda C. Gabriel et al.

NUTRITION RESEARCH (2019)

Review Immunology

Dietary Habits and Intestinal Immunity: From Food Intake to CD4+ TH Cells

Francesco Siracusa et al.

FRONTIERS IN IMMUNOLOGY (2019)

Article Surgery

Genetic and Environmental Considerations for Inflammatory Bowel Disease

Angela Kuhnen

SURGICAL CLINICS OF NORTH AMERICA (2019)

Review Medicine, General & Internal

The Role of the Gut Microbiota in Lipid and Lipoprotein Metabolism

Yijing Yu et al.

JOURNAL OF CLINICAL MEDICINE (2019)

Editorial Material Gastroenterology & Hepatology

Increasing Incidence of Pediatric Inflammatory Bowel Disease in France: Implications for Etiology, Diagnosis, Prognosis, and Treatment

Edward L. Barnes et al.

AMERICAN JOURNAL OF GASTROENTEROLOGY (2018)

Article Gastroenterology & Hepatology

The impact of short-chain fatty acids on GLP-1 and PYY secretion from the isolated perfused rat colon

Charlotte Bayer Christiansen et al.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2018)

Review Biochemistry & Molecular Biology

Oxidative Stress and Inflammation Induced by Environmental and Psychological Stressors: A Biomarker Perspective

Pietro Ghezzi et al.

ANTIOXIDANTS & REDOX SIGNALING (2018)

Article Biochemistry & Molecular Biology

Omega-6 fatty acids and inflammation

Jacqueline K. Innes et al.

PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS (2018)

Article Biochemistry & Molecular Biology

Probiotics SOD inhibited food allergy via downregulation of STAT6-TIM4 signaling on DCs

Bo Yang et al.

MOLECULAR IMMUNOLOGY (2018)

Article Multidisciplinary Sciences

SCFAs strongly stimulate PYY production in human enteroendocrine cells

P. Larraufie et al.

SCIENTIFIC REPORTS (2018)

Review Oncology

Management of Advanced Small Bowel Cancer

Alberto Puccini et al.

CURRENT TREATMENT OPTIONS IN ONCOLOGY (2018)

Review Biochemistry & Molecular Biology

Lipid Peroxidation-Derived Aldehydes, 4-Hydroxynonenal and Malondialdehyde in Aging-Related Disorders

Giuseppina Barrera et al.

ANTIOXIDANTS (2018)

Review Medicine, General & Internal

Omega-3 fatty acids for the primary and secondary prevention of cardiovascular disease

Asmaa S. Abdelhamid et al.

COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2018)

Review Gastroenterology & Hepatology

Microbiota metabolite short chain fatty acids, GPCR, and inflammatory bowel diseases

Mingming Sun et al.

JOURNAL OF GASTROENTEROLOGY (2017)

Article Gastroenterology & Hepatology

Probiotics in Inflammatory Bowel Disease

Bincy P. Abraham et al.

GASTROENTEROLOGY CLINICS OF NORTH AMERICA (2017)

Article Biochemistry & Molecular Biology

Butyric acid regulates progesterone and estradiol secretion via cAMP signaling pathway in porcine granulosa cells

Naisheng Lu et al.

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2017)

Review Medicine, General & Internal

Ulcerative colitis

Ryan Ungaro et al.

LANCET (2017)

Review Nutrition & Dietetics

Mediterranean diet and colorectal cancer: A systematic review

Alberto Farinetti et al.

NUTRITION (2017)

Article Gastroenterology & Hepatology

Cholesterol and Lipoprotein Metabolism and Atherosclerosis: Recent Advances in Reverse Cholesterol Transport

Helen H. Wang et al.

ANNALS OF HEPATOLOGY (2017)

Review Biochemistry & Molecular Biology

Omega-3 fatty acids and inflammatory processes: from molecules to man

Philip C. Calder

BIOCHEMICAL SOCIETY TRANSACTIONS (2017)

Article Microbiology

Microbial Interactions and Interventions in Colorectal Cancer

Terence Van Raay et al.

MICROBIOLOGY SPECTRUM (2017)

Article Nutrition & Dietetics

Alterations in human milk leptin and insulin are associated with early changes in the infant intestinal microbiome

Dominick J. Lemas et al.

AMERICAN JOURNAL OF CLINICAL NUTRITION (2016)

Article Physiology

Dietary α-linolenic acid supplementation alters skeletal muscle plasma membrane lipid composition, sarcolemmal FAT/CD36 abundance, and palmitate transport rates

Zane Chorner et al.

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2016)

Review Gastroenterology & Hepatology

Emerging Roles for Noncanonical NF-κB Signaling in the Modulation of Inflammatory Bowel Disease Pathobiology

Dylan K. McDaniel et al.

INFLAMMATORY BOWEL DISEASES (2016)

Review Immunology

Mucosal Interactions between Genetics, Diet, and Microbiome in Inflammatory Bowel Disease

Abigail Basson et al.

FRONTIERS IN IMMUNOLOGY (2016)

Review Gastroenterology & Hepatology

Consequences of bile salt biotransformations by intestinal bacteria

Jason M. Ridlon et al.

GUT MICROBES (2016)

Article Dentistry, Oral Surgery & Medicine

Periodontal Pathogen Accelerates Lipid Peroxidation and Atherosclerosis

R. Jia et al.

JOURNAL OF DENTAL RESEARCH (2013)

Review Cell Biology

LOX-1, OxLDL, and Atherosclerosis

Angela Pirillo et al.

MEDIATORS OF INFLAMMATION (2013)