Journal
FRONTIERS IN NUTRITION
Volume 9, Issue -, Pages -Publisher
FRONTIERS MEDIA SA
DOI: 10.3389/fnut.2022.849582
Keywords
black tea; diet-induced obesity; fatty liver; lipid metabolism; fecal excretion
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Funding
- Key Research and Development Program of Anhui Province [201904b11020038]
- Natural Science Foundation of Anhui province, China [2108085MC119]
- National Natural Science Foundation [31972459]
- National Sciences Foundation of China [U19A2034]
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This study analyzed the chemical compositions of Keemun black tea and Dianhong black tea and investigated their lipid-lowering effects in a high-fat diet mouse model. The results showed that Dianhong black tea was more effective in preventing hepatic fat accumulation and stimulating fecal fat excretion compared to Keemun black tea.
The chemical compositions of black teas differ greatly and may have different health benefits; however, systematic investigations into such benefits are lacking. Here, the chemical profiles of Keemun black tea (KBT) and Dianhong black tea (DBT), two common categories of tea in China, were analyzed, and their lipid-lowering effects in male C57BL/6 mice fed a high-fat diet (60% energy from fat) or the diet supplemented with 2% black tea powder for 15 weeks were investigated. The compounds most crucial in differentiating KBT and DBT were determined to be phenolic compounds, theanine, and D-psicose. DBT was more effective than KBT in preventing excess hepatic fat accumulation. Both black teas effectively and comparably altered the mRNA levels of hepatic lipid-metabolizing genes. DBT had more favorable effects in stimulating fecal fat excretion than did KBT. The differentiating compounds with the higher values of variable importance in the projection (VIP) might predominantly contribute to the different health benefits; however, the most essential compound or combination of compounds requires clarification.
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