Related references
Note: Only part of the references are listed.The far C-terminus of MCAK regulates its conformation and spindle pole focusing
Hailing Zong et al.
MOLECULAR BIOLOGY OF THE CELL (2016)
NuSAP modulates the dynamics of kinetochore microtubules by attenuating MCAK depolymerisation activity
Chenyu Li et al.
SCIENTIFIC REPORTS (2016)
The C-terminal region of the motor protein MCAK controls its structure and activity through a conformational switch
Sandeep K. Talapatra et al.
ELIFE (2015)
The mesh is a network of microtubule connectors that stabilizes individual kinetochore fibers of the mitotic spindle
Faye M. Nixon et al.
ELIFE (2015)
Mitotic centromere-associated kinesin (MCAK): a potential cancer drug target
Mourad Sanhaji et al.
Oncotarget (2015)
The mitotic origin of chromosomal instability
Samuel F. Bakhoum et al.
CURRENT BIOLOGY (2014)
Rac1 and Aurora A regulate MCAK to polarize microtubule growth in migrating endothelial cells
Alexander Braun et al.
JOURNAL OF CELL BIOLOGY (2014)
Kinetochore genes are coordinately up-regulated in human tumors as part of a FoxM1-related cell division program
Prathapan Thiru et al.
MOLECULAR BIOLOGY OF THE CELL (2014)
Increased microtubule assembly rates influence chromosomal instability in colorectal cancer cells
Norman Ertych et al.
NATURE CELL BIOLOGY (2014)
Easy quantitative assessment of genome editing by sequence trace decomposition
Eva K. Brinkman et al.
NUCLEIC ACIDS RESEARCH (2014)
Nucleotide Exchange in Dimeric MCAK Induces Longitudinal and Lateral Stress at Microtubule Ends to Support Depolymerization
Kyle M. Burns et al.
STRUCTURE (2014)
Aurora B Inhibits MCAK Activity through a Phosphoconformational Switch that Reduces Microtubule Association
Stephanie C. Ems-McClung et al.
CURRENT BIOLOGY (2013)
Coordination of adjacent domains mediates TACC3-ch-TOG-clathrin assembly and mitotic spindle binding
Fiona E. Hood et al.
JOURNAL OF CELL BIOLOGY (2013)
Specific removal of TACC3-ch-TOG-clathrin at metaphase deregulates kinetochore fiber tension
Liam P. Cheeseman et al.
JOURNAL OF CELL SCIENCE (2013)
Genome engineering using the CRISPR-Cas9 system
F. Ann Ran et al.
NATURE PROTOCOLS (2013)
The cancer biology of whole-chromosome instability
P. H. G. Duijf et al.
ONCOGENE (2013)
Multiplex Genome Engineering Using CRISPR/Cas Systems
Le Cong et al.
SCIENCE (2013)
A double-edged sword: how oncogenes and tumor suppressor genes can contribute to chromosomal instability
Bernardo Orr et al.
FRONTIERS IN ONCOLOGY (2013)
Doublecortin Recognizes the 13-Protofilament Microtubule Cooperatively and Tracks Microtubule Ends
Susanne Bechstedt et al.
DEVELOPMENTAL CELL (2012)
MCAK activity at microtubule tips regulates spindle microtubule length to promote robust kinetochore attachment
Sarah B. Domnitz et al.
JOURNAL OF CELL BIOLOGY (2012)
Mitotic spindle (DIS)orientation and DISease: Cause or consequence?
Anna Noatynska et al.
JOURNAL OF CELL BIOLOGY (2012)
High-efficiency counterselection recombineering for site-directed mutagenesis in bacterial artificial chromosomes
Alexander W. Bird et al.
NATURE METHODS (2012)
Causes and consequences of aneuploidy in cancer
David J. Gordon et al.
NATURE REVIEWS GENETICS (2012)
GTSE1 Is a Microtubule Plus-End Tracking Protein That Regulates EB1-Dependent Cell Migration
Massimilano Scolz et al.
PLOS ONE (2012)
A TACC3/ch-TOG/clathrin complex stabilises kinetochore fibres by inter-microtubule bridging
Daniel G. Booth et al.
EMBO JOURNAL (2011)
PLK1 Phosphorylates Mitotic Centromere-associated Kinesin and Promotes Its Depolymerase Activity
Liangyu Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Kif18B interacts with EB1 and controls astral microtubule length during mitosis
Jane R. Stout et al.
MOLECULAR BIOLOGY OF THE CELL (2011)
Nup98 regulates bipolar spindle assembly through association with microtubules and opposition of MCAK
Marie K. Cross et al.
MOLECULAR BIOLOGY OF THE CELL (2011)
K-fibre minus ends are stabilized by a RanGTP-dependent mechanism essential for functional spindle assembly
Sylvain Meunier et al.
NATURE CELL BIOLOGY (2011)
Long astral microtubules uncouple mitotic spindles from the cytokinetic furrow
Kathleen E. Rankin et al.
JOURNAL OF CELL BIOLOGY (2010)
Clathrin heavy chain mediates TACC3 targeting to mitotic spindles to ensure spindle stability
Chiou-Hong Lin et al.
JOURNAL OF CELL BIOLOGY (2010)
Quantitative proteomics combined with BAC TransgeneOmics reveals in vivo protein interactions
Nina C. Hubner et al.
JOURNAL OF CELL BIOLOGY (2010)
Clathrin recruits phosphorylated TACC3 to spindle poles for bipolar spindle assembly and chromosome alignment
Wenxiang Fu et al.
JOURNAL OF CELL SCIENCE (2010)
Functional and Spatial Regulation of Mitotic Centromere-Associated Kinesin by Cyclin-Dependent Kinase 1
Mourad Sanhaji et al.
MOLECULAR AND CELLULAR BIOLOGY (2010)
Catalysis of the microtubule on-rate is the major parameter regulating the depolymerase activity of MCAK
Jeremy R. Cooper et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2010)
Mitotic chromosomal instability and cancer: mouse modelling of the human disease
Juan-Manuel Schvartzman et al.
NATURE REVIEWS CANCER (2010)
Deviant Kinetochore Microtubule Dynamics Underlie Chromosomal Instability
Samuel F. Bakhoum et al.
CURRENT BIOLOGY (2009)
TIP150 interacts with and targets MCAK at the microtubule plus ends
Kai Jiang et al.
EMBO REPORTS (2009)
MCAK and Paclitaxel Have Differential Effects on Spindle Microtubule Organization and Dynamics
Rania S. Rizk et al.
MOLECULAR BIOLOGY OF THE CELL (2009)
Genome stability is ensured by temporal control of kinetochore-microtubule dynamics
Samuel F. Bakhoum et al.
NATURE CELL BIOLOGY (2009)
Building a spindle of the correct length in human cells requires the interaction between TPX2 and Aurora A
Alexander W. Bird et al.
JOURNAL OF CELL BIOLOGY (2008)
Examining the link between chromosomal instability and aneuploidy in human cells
Sarah L. Thompson et al.
JOURNAL OF CELL BIOLOGY (2008)
BAC TransgeneOmics:: a high-throughput method for exploration of protein function in mammals
Ina Poser et al.
NATURE METHODS (2008)
Aurora B phosphorylates multiple sites on mitotic centromere-associated kinesin to spatially and temporally regulate its function
Xin Zhang et al.
MOLECULAR BIOLOGY OF THE CELL (2007)
Protein complex expression by using multigene baculoviral vectors
Daniel J. Fitzgerald et al.
NATURE METHODS (2006)
A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers
Scott L. Carter et al.
NATURE GENETICS (2006)
The depolymerizing kinesin MCAK uses lattice diffusion to rapidly target microtubule ends
J Helenius et al.
NATURE (2006)
Aurora A phosphorylation of TACC3/maskin is required for centrosome-dependent microtubule assembly in mitosis
K Kinoshita et al.
JOURNAL OF CELL BIOLOGY (2005)
Depletion of centromeric MCAK leads to chromosome congression and segregation defects due to improper kinetochore attachments
SL Kline-Smith et al.
MOLECULAR BIOLOGY OF THE CELL (2004)
Aurora B regulates MCAK at the mitotic centromere
PD Andrews et al.
DEVELOPMENTAL CELL (2004)
Spindle checkpoint protein dynamics at kinetochores in living cells
BJ Howell et al.
CURRENT BIOLOGY (2004)
Dynamic microtubules lead the way for spindle positioning
CG Pearson et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2004)
C-terminus of mitotic centromere-associated kinesin (MCAK) inhibits its lattice-stimulated ATPase activity
A Moore et al.
BIOCHEMICAL JOURNAL (2004)
Aurora-a kinase maintains the fidelity of early and late mitotic events in HeLa cells
T Marumoto et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Purification of brain tubulin through two cycles of polymerization-depolymerization in a high-molarity buffer
M Castoldi et al.
PROTEIN EXPRESSION AND PURIFICATION (2003)
The cell cycle-regulated protein human GTSE-1 controls DNA damage-induced apoptosis by affecting p53 function
M Monte et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
An inner centromere protein that stimulates the microtubule depolymerizing activity of a Kinl kinesin
R Ohi et al.
DEVELOPMENTAL CELL (2003)
The kinesin-related protein MCAK is a microtubule depolymerase that forms an ATP-hydrolyzing complex at microtubule ends
AW Hunter et al.
MOLECULAR CELL (2003)
The microtubule-destabilizing kinesin XKCM1 is required for chromosome positioning during spindle assembly
CE Walczak et al.
CURRENT BIOLOGY (2002)
Drosophila Aurora A kinase is required to localize D-TACC to centrosomes and to regulate astral microtubules
R Giet et al.
JOURNAL OF CELL BIOLOGY (2002)
Cloning, chromosome mapping and functional characterization of a human homologue of murine Gtse-1 (B99) gene
M Monte et al.
GENE (2000)