Role of imaging in rare COVID-19 vaccine multiorgan complications

As of September 18th, 2021, global casualties due to COVID-19 infections approach 200 million, several COVID-19 vaccines have been authorized to prevent COVID-19 infection and help mitigate the spread of the virus. Despite the vast majority having safely received vaccination against SARS-COV-2, the rare complications following COVID-19 vaccination have often been life-threatening or fatal. The mechanisms underlying (multi) organ complications are associated with COVID-19, either through direct viral damage or from host immune response (i.e., cytokine storm). The purpose of this manuscript is to review the role of imaging in identifying and elucidating multiorgan complications following SARS-COV-2 vaccination-making clear that, in any case, they represent a minute fraction of those in the general population who have been vaccinated. The authors are both staunch supporters of COVID-19 vaccination and vaccinated themselves as well.

Automated summary

As of September 18th, 2021, there have been nearly 200 million global casualties due to COVID-19 infections. While several vaccines have been authorized to prevent COVID-19 infection, rare complications following vaccination have been reported to be life-threatening or fatal. This manuscript reviews the role of imaging in identifying and understanding multiorgan complications following SARS-COV-2 vaccination, emphasizing that these complications represent a small fraction among the vaccinated population. The authors of the manuscript are supporters of COVID-19 vaccination and have been vaccinated themselves.