4.7 Article

A Scoping Review of Attitudes and Experiences with Pharmacogenomic Testing among Patients and the General Public: Implications for Patient Counseling

Related references

Note: Only part of the references are listed.
Article Genetics & Heredity

Nine-gene pharmacogenomics profile service: The Mayo Clinic experience

Eric T. Matey et al.

Summary: The Pharmacogenomics (PGx) Profile Service at Mayo Clinic demonstrated that pre-emptive PGx testing could improve medication outcomes for 56% of participants. The collaborative approach involving a PGx pharmacist integrated within clinical practice facilitated the implementation of the PGx Profile Service.

PHARMACOGENOMICS JOURNAL (2022)

Article Public, Environmental & Occupational Health

Communicating unexpected pharmacogenomic results to biobank contributors: A focus group study

Karen M. Meagher et al.

Summary: This study used qualitative focus group research to explore the impact of returning unexpected pharmacogenomic results to biobank contributors. Participants showed high valuation of the results, especially in terms of health identity and sharing information with family members. They highlighted the need for clear clinical translation messaging and identified barriers to transferring research results to a clinical context.

PATIENT EDUCATION AND COUNSELING (2021)

Review Pharmacology & Pharmacy

Synthesis of major pharmacogenomics pretest counseling themes: a multisite comparison

Dyson T. Wake et al.

Summary: The accessibility of pharmacogenomic (PGx) testing has increased, leading to a demand for patient counseling. While guidelines exist, objective criteria for who should receive testing are incomplete, and there is significant variability between PGx clinical services.

PHARMACOGENOMICS (2021)

Article Pharmacology & Pharmacy

North Carolina's multi-institutional pharmacogenomics efforts with the NC precision health collaborative

Jai N. Patel et al.

Summary: The North Carolina precision health collaborative is a public-private consortium that strategically aligns statewide resources and strengths to elevate precision health. Pharmacogenomics is a key area of focus, with experts from multiple organizations collaborating since 2017 to implement strategic PGx initiatives. This institutional profile highlights major PGx programs and initiatives across these institutions and how the Collaborative is working together to advance PGx science and implementation.

PHARMACOGENOMICS (2021)

Article Genetics & Heredity

Impact of Previous Genetic Counseling and Objective Numeracy on Accurate Interpretation of a Pharmacogenetics Test Report

Kelly Drelles et al.

Summary: Numeracy significantly impacted the correct interpretation of PGx test reports, with individuals of high numeracy performing better in interpretation and genetic knowledge questions. Prior genetic counseling did not have an impact on test interpretation or genetic knowledge.

PUBLIC HEALTH GENOMICS (2021)

Article Medicine, Research & Experimental

Pharmacogenomics guided versus standard antidepressant treatment in a community pharmacy setting: A randomized controlled trial

John Papastergiou et al.

Summary: The study evaluated the impact of pharmacogenomics guided versus standard antidepressant treatment for depression and anxiety, finding that pharmacogenomics guided treatment was more effective in improving depression, generalized anxiety, and disability outcomes. Treatment satisfaction showed similar improvements for both groups.

CTS-CLINICAL AND TRANSLATIONAL SCIENCE (2021)

Article Pharmacology & Pharmacy

Sociodemographic factors and beliefs about medicines in the uptake of pharmacogenomic testing in older adults

Alexandra Chapdelaine et al.

Summary: The study revealed that increased age and negative beliefs about the harmfulness of medicines can decrease the willingness of older adults to undergo pharmacogenomic testing, while lower education level was associated with a decreased willingness to pay for the testing.

PHARMACOGENOMICS (2021)

Article Pharmacology & Pharmacy

Implementation of a pharmacist-provided pharmacogenomics service in an executive health program

Ina Liko et al.

Summary: The implementation of pharmacist-provided pharmacogenomics service in an executive health program was successful, allowing pharmacists to lead efforts and collaborate with physicians to expand precision medicine at an academic medical center.

AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY (2021)

Article Genetics & Heredity

Development and Implementation of In-House Pharmacogenomic Testing Program at a Major Academic Health System

Pawel Mroz et al.

Summary: Pharmacogenomics focuses on how individual genes influence responses to medications, playing a key role in precision medicine. While clinical application of PGx principles shows promise in improving therapeutic outcomes, translating complex genetic information into actionable recommendations remains a significant technical challenge. Nevertheless, successful implementation in a clinical setting requires overcoming various hurdles in molecular diagnostics, healthcare systems, and provider and patient education.

FRONTIERS IN GENETICS (2021)

Article Pharmacology & Pharmacy

Adolescent perceptions of pharmacogenetic testing

Stephani L. Stancil et al.

Summary: Overall, adolescents in this study showed positive understanding and perceptions of PGx testing, believing it to be useful, low risk, and beneficial to their peers.

PHARMACOGENOMICS (2021)

Editorial Material Medicine, Research & Experimental

Pharmacists as facilitators of pharmacogenomic guidance for antidepressant drug selection and dosing

Jeffrey R. Bishop

CTS-CLINICAL AND TRANSLATIONAL SCIENCE (2021)

Review Pharmacology & Pharmacy

Pharmacogenomic testing to support prescribing in primary-care: a structured review of implementation models

Judith Hayward et al.

Summary: The application of pharmacogenomics in primary care can contribute to medication optimization. Studies on utilization of multi-gene pharmacogenomic panels in primary care settings highlighted the importance and feasibility of pre-test counseling, pharmacist involvement, and integration of data into electronic records and CDSS for personalized treatment.

PHARMACOGENOMICS (2021)

Article Pharmacology & Pharmacy

Pharmacogenomics education, research and clinical implementation in the state of Minnesota

Jeffrey R. Bishop et al.

Summary: Several healthcare organizations in Minnesota have established formal pharmacogenomic clinical programs to enhance drug safety and efficacy. Healthcare professionals and students are receiving strong education in this field, with multiple opportunities available for gaining workforce skills and advanced competency. The state has seen important discoveries in therapeutic areas through laboratory-based and translational pharmacogenomic research.

PHARMACOGENOMICS (2021)

Article Health Care Sciences & Services

Strategies to Integrate Genomic Medicine into Clinical Care: Evidence from the IGNITE Network

Nina R. Sperber et al.

Summary: The complexity of genomic medicine can be simplified by implementing clinical decision support (CDS) to guide clinicians in utilizing personalized data; a study found that pharmacogenomics projects used more strategies than disease-focused projects; understanding the successful application of strategies in pharmacogenomics projects could be beneficial for implementing genomic or precision medicine programs in different contexts.

JOURNAL OF PERSONALIZED MEDICINE (2021)

Article Public, Environmental & Occupational Health

Patient perceptions of pharmacogenomic testing in the community pharmacy setting

David Bright et al.

Summary: Through semi-structured face-to-face interviews with adults over 18 years of age, it was found that patient perceptions of PGx testing in the community pharmacy setting centered around four themes: trust, experience, risk/benefit, and clarity. These themes may impact patients' willingness to undergo PGx testing.

RESEARCH IN SOCIAL & ADMINISTRATIVE PHARMACY (2021)

Article Medicine, Research & Experimental

Assessment of Patient Knowledge and Perceptions of Pharmacogenomics Before and After Using a Mock Results Patient Web Portal

Tien M. Truong et al.

CTS-CLINICAL AND TRANSLATIONAL SCIENCE (2020)

Article Genetics & Heredity

Implementation of Pharmacogenetics in Primary Care: A Multi-Stakeholder Perspective

Tessel Rigter et al.

FRONTIERS IN GENETICS (2020)

Article Pharmacology & Pharmacy

An assessment of patient perspectives on pharmacogenomics educational materials

Gladys B. Asiedu et al.

PHARMACOGENOMICS (2020)

Article Medicine, General & Internal

Design and Early Implementation Successes and Challenges of a Pharmacogenetics Consult Clinic

Meghan J. Arwood et al.

JOURNAL OF CLINICAL MEDICINE (2020)

Article Health Care Sciences & Services

Pharmacogenomic (PGx) Counseling: Exploring Participant Questions about PGx Test Results

Tara Schmidlen et al.

JOURNAL OF PERSONALIZED MEDICINE (2020)

Article Biotechnology & Applied Microbiology

Patient insights on features of an effective pharmacogenomics patient portal

Tien M. Truong et al.

PHARMACOGENETICS AND GENOMICS (2020)

Article Pharmacology & Pharmacy

Patients' Perspectives on Psychiatric Pharmacogenetic Testing

Ina Liko et al.

PHARMACOPSYCHIATRY (2020)

Article Cardiac & Cardiovascular Systems

Perspective on CYP2C19 genotyping test among patients with acute coronary syndrome - a qualitative study

Wan Yu Png et al.

FUTURE CARDIOLOGY (2020)

Review Health Care Sciences & Services

Updated methodological guidance for the conduct of scoping reviews

Micah D. J. Peters et al.

JBI EVIDENCE SYNTHESIS (2020)

Article Biotechnology & Applied Microbiology

International survey of patients undergoing percutaneous coronary intervention and their attitudes toward pharmacogenetic testing

Naveen L. Pereira et al.

PHARMACOGENETICS AND GENOMICS (2019)

Article Pharmacology & Pharmacy

Implementing pharmacogenetic testing in rural primary care practices: a pilot feasibility study

Lynn G. Dressler et al.

PHARMACOGENOMICS (2019)

Article Pharmacology & Pharmacy

Pharmacogenetic testing in primary care practice: opinions of physicians, pharmacists and patients

Marie-Pier Frigon et al.

PHARMACOGENOMICS (2019)

Article Pharmacology & Pharmacy

Stakeholder perspectives of the clinical utility of pharmacogenomic testing in solid organ transplantation

Kimberly M. Deininger et al.

PHARMACOGENOMICS (2019)

Article Health Care Sciences & Services

Description of an Established, Fee-for-Service, Office-Based, Pharmacist-Managed Pharmacogenomics Practice

Michael J. Schuh et al.

SENIOR CARE PHARMACIST (2019)

Editorial Material Pharmacology & Pharmacy

Education and Knowledge in Pharmacogenomics: Still a Challenge?

Jyothsna Giri et al.

CLINICAL PHARMACOLOGY & THERAPEUTICS (2018)

Article Medicine, Research & Experimental

Developing Pharmacogenomic Reports: Insights from Patients and Clinicians

Laney K. Jones et al.

CTS-CLINICAL AND TRANSLATIONAL SCIENCE (2018)

Article Multidisciplinary Sciences

Awareness and attitude of the public toward personalized medicine in Korea

Iyn-Hyang Lee et al.

PLOS ONE (2018)

Article Medicine, General & Internal

PRISMA Extension for Scoping Reviews (PRISMA-ScR): Checklist and Explanation

Andrea C. Tricco et al.

ANNALS OF INTERNAL MEDICINE (2018)

Review Health Care Sciences & Services

Systematic review or scoping review? Guidance for authors when choosing between a systematic or scoping review approach

Zachary Munn et al.

BMC MEDICAL RESEARCH METHODOLOGY (2018)

Article Pharmacology & Pharmacy

Qualitative user evaluation of a revised pharmacogenetic educational toolkit

Rachel Mills et al.

PHARMACOGENOMICS & PERSONALIZED MEDICINE (2018)

Article Biotechnology & Applied Microbiology

Assessment of patient perceptions of genomic testing to inform pharmacogenomic implementation

Yee Ming Lee et al.

PHARMACOGENETICS AND GENOMICS (2017)

Article Pharmacology & Pharmacy

Pharmacogenomics testing in a community pharmacy: patient perceptions and willingness-to-pay

Mara L. Gibson et al.

PHARMACOGENOMICS (2017)

Article Pharmacology & Pharmacy

Clinicians' perceptions of pharmacogenomics use in psychiatry

Christopher Yi Wen Chan et al.

PHARMACOGENOMICS (2017)

Article Pharmacology & Pharmacy

Collaborative Counseling Considerations for Pharmacogenomic Tests

Heather A. Zierhut et al.

PHARMACOTHERAPY (2017)

Article Health Care Sciences & Services

Development and Initial Assessment of a Patient Education Video about Pharmacogenetics

Rachel Mills et al.

JOURNAL OF PERSONALIZED MEDICINE (2017)

Article Genetics & Heredity

Measuring genetic knowledge: a brief survey instrument for adolescents and adults

S. M. Fitzgerald-Butt et al.

CLINICAL GENETICS (2016)

Article Pharmacology & Pharmacy

Implementation of a multidisciplinary pharmacogenomics clinic in a community health system

Henry M. Dunnenberger et al.

AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY (2016)

Article Pharmacology & Pharmacy

Patient experiences with pharmacogenetic testing in a primary care setting

Susanne B. Haga et al.

PHARMACOGENOMICS (2016)

Review Pharmacology & Pharmacy

Preemptive Clinical Pharmacogenetics Implementation: Current Programs in Five US Medical Centers

Henry M. Dunnenberger et al.

ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 55 (2015)

Article Pharmacology & Pharmacy

Stakeholder Views on Pharmacogenomic Testing

Haridarshan N. Patel et al.

PHARMACOTHERAPY (2014)

Article Public, Environmental & Occupational Health

Risk, Reward, and the Double-Edged Sword: Perspectives on Pharmacogenetic Research and Clinical Testing Among Alaska Native People

Jennifer L. Shaw et al.

AMERICAN JOURNAL OF PUBLIC HEALTH (2013)

Article Genetics & Heredity

Survey of US public attitudes toward pharmacogenetic testing

S. B. Haga et al.

PHARMACOGENOMICS JOURNAL (2012)

Article Genetics & Heredity

Factors Influencing Uptake of Pharmacogenetic Testing in a Diverse Patient Population

J. O'Daniel et al.

PUBLIC HEALTH GENOMICS (2010)

Article Public, Environmental & Occupational Health

Consumers' views of pharmacogenetics-A qualitative study

Catherine A. Haddy et al.

RESEARCH IN SOCIAL & ADMINISTRATIVE PHARMACY (2010)

Article Genetics & Heredity

The rapid estimate of adult literacy in genetics (REAL-G): A means to assess literacy deficits in the context of genetics

Lori H. Erby et al.

AMERICAN JOURNAL OF MEDICAL GENETICS PART A (2008)