4.7 Article

Stathmins and Motor Neuron Diseases: Pathophysiology and Therapeutic Targets

Related references

Note: Only part of the references are listed.
Article Cell Biology

Diagnostic and prognostic value of CSF neurofilaments in a cohort of patients with motor neuron disease: A cross-sectional study

Delia Gagliardi et al.

Summary: CSF neurofilaments such as p-NfH and NfL levels are significantly correlated with ALS progression rate, reflecting the burden of neurodegeneration and serving as reliable diagnostic and prognostic biomarkers in ALS.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2021)

Article Geriatrics & Gerontology

Novel STMN2 Variant Linked to Amyotrophic Lateral Sclerosis Risk and Clinical Phenotype

Frances Theunissen et al.

Summary: This study identified a novel non-coding CA repeat in Stathmin-2 associated with sALS disease risk. The long/long genotype was significantly associated with disease risk, with longer CA allele length linked to earlier age-of-onset and shorter survival duration.

FRONTIERS IN AGING NEUROSCIENCE (2021)

Review Neurosciences

Anatomo-Functional Origins of the Cortical Silent Period: Spotlight on the Basal Ganglia

David Zeugin et al.

Summary: The cortical silent period (CSP) is a temporary interruption of muscle signal following TMS-induced MEP. CSP duration is influenced by both spinal and cortical mechanisms, as well as contextual factors like cortical fatigue, experimental procedures, attentional load, and neuropathology. The central role of the basal ganglia in managing cortical motor inhibition through various pathways may contribute to understanding the mechanisms underlying CSP's duration.

BRAIN SCIENCES (2021)

Article Clinical Neurology

Synaptotagmin 13 is neuroprotective across motor neuron diseases

M. Nizzardo et al.

ACTA NEUROPATHOLOGICA (2020)

Article Medicine, Research & Experimental

Truncated stathmin-2 is a marker of TDP-43 pathology in frontotemporal dementia

Mercedes Prudencio et al.

JOURNAL OF CLINICAL INVESTIGATION (2020)

Editorial Material Medicine, Research & Experimental

Stathmin-2: adding another piece to the puzzle of TDP-43 proteinopathies and neurodegeneration

Jonathan D. Glass

JOURNAL OF CLINICAL INVESTIGATION (2020)

Article Biochemistry & Molecular Biology

AAV9-Stathmin1 gene delivery improves disease phenotype in an intermediate mouse model of spinal muscular atrophy

E. Villalon et al.

HUMAN MOLECULAR GENETICS (2019)

Article Multidisciplinary Sciences

The landscape of multiscale transcriptomic networks and key regulators in Parkinson's disease

Qian Wang et al.

NATURE COMMUNICATIONS (2019)

Article Neurosciences

Stathmin 1/2-triggered microtubule loss mediates Golgi fragmentation in mutant SOD1 motor neurons

Sarah Bellouze et al.

MOLECULAR NEURODEGENERATION (2016)

Article Multidisciplinary Sciences

Differential neuronal vulnerability identifies IGF-2 as a protective factor in ALS

Ilary Allodi et al.

SCIENTIFIC REPORTS (2016)

Review Neurosciences

Building the Neuronal Microtubule Cytoskeleton

Lukas C. Kapitein et al.

NEURON (2015)

Article Neurosciences

Dynamic regulation of SCG10 in regenerating axons after injury

Jung Eun Shin et al.

EXPERIMENTAL NEUROLOGY (2014)

Article Clinical Neurology

Progressive amnestic dementia, hippocampal sclerosis, and mutation in C9ORF72

Melissa E. Murray et al.

ACTA NEUROPATHOLOGICA (2013)

Article Biochemistry & Molecular Biology

The intriguing case of motor neuron disease: ALS and SMA come closer

Tilmann Achsel et al.

BIOCHEMICAL SOCIETY TRANSACTIONS (2013)

Article Biochemistry & Molecular Biology

Severe neuromuscular denervation of clinically relevant muscles in a mouse model of spinal muscular atrophy

Karen K. Y. Ling et al.

HUMAN MOLECULAR GENETICS (2012)

Review Neurosciences

Gains or losses: molecular mechanisms of TDP43-mediated neurodegeneration

Edward B. Lee et al.

NATURE REVIEWS NEUROSCIENCE (2012)

Article Cell Biology

Genetic Correction of Human Induced Pluripotent Stem Cells from Patients with Spinal Muscular Atrophy

Stefania Corti et al.

SCIENCE TRANSLATIONAL MEDICINE (2012)

Article Biochemistry & Molecular Biology

The Dying-Back Phenomenon of Motor Neurons in ALS

Michal Dadon-Nachum et al.

JOURNAL OF MOLECULAR NEUROSCIENCE (2011)

Article Neurosciences

Stathmin is Required for Stability of the Drosophila Neuromuscular Junction

Ethan R. Graf et al.

JOURNAL OF NEUROSCIENCE (2011)

Article Biochemistry & Molecular Biology

Stathmin, a microtubule-destabilizing protein, is dysregulated in spinal muscular atrophy(dagger)

Hsin-Lan Wen et al.

HUMAN MOLECULAR GENETICS (2010)

Review Biochemistry & Molecular Biology

TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration

Clotilde Lagier-Tourenne et al.

HUMAN MOLECULAR GENETICS (2010)

Article Immunology

The Microtubule Regulator Stathmin Is an Endogenous Protein Agonist for TLR3

Malika Bsibsi et al.

JOURNAL OF IMMUNOLOGY (2010)

Review Clinical Neurology

Axonal degeneration in motor neuron disease

Lindsey R. Fischer et al.

NEURODEGENERATIVE DISEASES (2007)

Article Cell Biology

JNK1 phosphorylation of SCG10 determines microtubule dynamics and axodendritic length

T Tararuk et al.

JOURNAL OF CELL BIOLOGY (2006)

Article Biochemistry & Molecular Biology

The role of stathmin in the regulation of the cell cycle

CI Rubin et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2004)

Article Biochemistry & Molecular Biology

Phosphorylation disrupts the central helix in Op18/stathmin and suppresses binding to tubulin

MO Steinmetz et al.

EMBO REPORTS (2001)

Article Clinical Neurology

New ocular movement detector system as a communication tool in ventilator-assisted Werdnig-Hoffmann disease

M Kubota et al.

DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY (2000)