Clinical Interest of Serum Alpha-2 Macroglobulin, Apolipoprotein A1, and Haptoglobin in Patients with Non-Alcoholic Fatty Liver Disease, with and without Type 2 Diabetes, before or during COVID-19

Article Endocrinology & Metabolism

Acute-to-Chronic Glycemic Ratio as a Predictor of COVID-19 Severity and Mortality

Jordi Ramon et al.

Summary: The imbalance between acute glycemia and chronic metabolic control is associated with worse prognosis for patients with type 2 diabetes hospitalized with COVID-19.

DIABETES CARE (2022)

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Review Gastroenterology & Hepatology

Epidemiology and disease burden of non-alcoholic steatohepatitis in greater China: a systematic review

Huimin Zou et al.

Summary: This is the first comprehensive overview of NASH among the Chinese population, revealing an overwhelming impact of social and healthcare burden associated with the condition. Further high-quality studies are needed to improve the understanding and management of NASH in greater China.

HEPATOLOGY INTERNATIONAL (2022)

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Article Gastroenterology & Hepatology

Burden of liver disease progression in hospitalized patients with type 2 diabetes mellitus

Vincent Mallet et al.

Summary: This study investigates the risks of liver cancer and complications of liver disease in patients with type 2 diabetes. The findings suggest that alcohol use disorders are the main factor associated with complications of liver disease.

JOURNAL OF HEPATOLOGY (2022)

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Article Medicine, Research & Experimental

Impact of Metabolic Syndrome on Severity of COVID-19 Illness

Shannon Wu et al.

Summary: Metabolic syndrome is associated with higher hospitalization and mortality rates among patients with COVID-19, even after adjusting for other factors. Targeting modifiable risk factors such as obesity, hyperglycemia, dyslipidemia, and hypertension could help reduce mortality from COVID-19.

METABOLIC SYNDROME AND RELATED DISORDERS (2022)

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Article Multidisciplinary Sciences

Cross-sectional and longitudinal associations of apolipoprotein A1 and B with glycosylated hemoglobin in Chinese adults

Hongli Dong et al.

Summary: This study found that higher ApoA1, lower ApoB concentrations, and the ApoB/A1 ratio were associated with lower HbA1c levels in Chinese adults.

SCIENTIFIC REPORTS (2022)

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Article Biochemistry & Molecular Biology

Implication of Intestinal Barrier Dysfunction in Gut Dysbiosis and Diseases

Carmine Stolfi et al.

Summary: The intestinal mucosal barrier, known as intestinal barrier, plays a critical role in maintaining gut homeostasis by regulating the interaction between gut microbes and the host immune system. Genetic defects and environmental factors can disrupt this balance, leading to gut dysbiosis, inflammatory responses, and chronic pathological conditions. This review discusses the molecular and cellular pathways involved in maintaining the structural and functional homeostasis of the intestinal barrier, with a focus on potential alterations that may disrupt this delicate balance.

BIOMEDICINES (2022)

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Article Nutrition & Dietetics

COVID-19 Risk Appears to Vary Across Different Alcoholic Beverages

Xi-jian Dai et al.

Summary: This study found associations between the status, amount, and frequency of different alcoholic beverages and COVID-19 risk and associated mortality. Red wine, white wine, and champagne have the potential to reduce the risk of COVID-19, while consumption of beer, cider, and spirits increases the risk.

FRONTIERS IN NUTRITION (2022)

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Article Endocrinology & Metabolism

Advanced Liver Fibrosis Is Associated with Chronic Kidney Disease in Patients with Type 2 Diabetes Mellitus and Nonalcoholic Fatty Liver Disease br

Da Hea Seo et al.

Summary: In patients with type 2 diabetes mellitus, advanced liver fibrosis in NAFLD is independently associated with an increased risk of incident CKD.

DIABETES & METABOLISM JOURNAL (2022)

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Article Gastroenterology & Hepatology

Pegbelfermin selectively reduces secondary bile acid concentrations in patients with non-alcoholic steatohepatitis

Yi Luo et al.

Summary: This study found that Pegbelfermin (PGBF) can reduce serum bile acid levels in patients with non-alcoholic steatohepatitis (NASH) and healthy overweight/obese adults. Furthermore, PGBF may have a potential role in modulating secondary bile acid synthesis by the gut microbiome.

JHEP REPORTS (2022)

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Article Gastroenterology & Hepatology

Independent Predictors of Mortality Among Patients With NAFLD Hospitalized With COVID-19 Infection

Zobair M. Younossi et al.

Summary: Patients with NAFLD infected with COVID-19 may present with more severe conditions upon admission and require increased hospital resource use. Independent predictors of mortality include higher FIB-4 and multimorbidity scores, morbid obesity, older age, and hypoxemia upon admission.

HEPATOLOGY COMMUNICATIONS (2022)

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Article Clinical Neurology

Obstructive sleep apnea, chronic obstructive pulmonary disease and NAFLD: an individual participant data meta-analysis

Ingrid Jullian-Desayes et al.

Summary: This study investigated the association between liver damage and the severity of obstructive sleep apnea (OSA) and chronic obstructive pulmonary disease (COPD) using individual participant data meta-analysis. The results confirmed a strong association between OSA severity and liver steatosis, with the relationship between OSA and fibrosis mainly attributed to BMI as shown by causal mediation analysis.

SLEEP MEDICINE (2021)

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Article Endocrinology & Metabolism

Impaired intestinal barrier function in type 2 diabetic patients measured by serum LPS, Zonulin, and IFABP

Jie-Hao Yuan et al.

Summary: The study reveals that the intestinal barrier function is impaired in patients with type 2 diabetes mellitus. Poor glycemic control and more chronic complications of diabetes are associated with worse intestinal barrier function. Treatment with aspirin does not worsen the impairment of intestinal barrier in patients with type 2 diabetes mellitus.

JOURNAL OF DIABETES AND ITS COMPLICATIONS (2021)

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Article Cardiac & Cardiovascular Systems

The role of the plasma glycosylated hemoglobin A1c/Apolipoprotein A-l ratio in predicting cardiovascular outcomes in acute coronary syndrome

Feier Song et al.

Summary: The study demonstrated that after adjusting for traditional cardiovascular risk factors, the HbA1c/ApoA-l ratio remains a predictor of all-cause mortality and major adverse cardiovascular events in ACS patients. Patients with higher HbA1c/ApoA-l ratio had a significantly increased risk of mortality compared to those with lower ratios.

NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES (2021)

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Article Biochemistry & Molecular Biology

Haptoglobin as a Biomarker

S. N. Naryzny et al.

Summary: Haptoglobin is a glycoprotein that binds free hemoglobin in plasma, playing a critical role in tissue protection and preventing oxidative damage. It is a conservative protein synthesized mainly in the liver and lungs, and is being studied as a potential biomarker for various diseases due to its structural and functional diversity. Studies show that the phenotype of haptoglobin can indicate an individual's predisposition to different diseases.

BIOCHEMISTRY MOSCOW-SUPPLEMENT SERIES B-BIOMEDICAL CHEMISTRY (2021)

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Article Gastroenterology & Hepatology

The Association of Histologic and Noninvasive Tests With Adverse Clinical and Patient-Reported Outcomes in Patients With Advanced Fibrosis Due to Nonalcoholic Steatohepatitis

Zobair M. Younossi et al.

Summary: In patients with advanced NASH, baseline NIT scores and their changes over time are predictive factors for adverse clinical and PROs outcomes. Patients with higher NIT scores are more likely to experience disease progression and impaired PROs, while those with decreasing NIT scores may see improvements in PRO scores.

GASTROENTEROLOGY (2021)

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Article Genetics & Heredity

Plasma Apolipoproteins A1/B and OxLDL Levels in Patients with Covid-19 As Possible Markers of the Disease

V. V. Pushkarev et al.

Summary: The study showed significant differences in the content of ApoA1, ApoB, and oxLDL in the plasma of patients with COVID-19, diabetes, and cardiovascular disease compared to healthy individuals. These lipid markers may serve as promising indicators of COVID-19 infection.

CYTOLOGY AND GENETICS (2021)

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Article Hematology

Thromboinflammation in COVID-19: Can α2-macroglobulin help to control the fire?

Rainer Seitz et al.

Summary: The complex COVID-19-associated coagulopathy may affect prognosis. Research suggests that children are somewhat protected from severe COVID-19 due to higher levels of alpha(2)-macroglobulin. Neutrophils, in addition to endothelial cells, thrombin, and platelets, also play a significant role in the disease.

JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2021)

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Article Biochemistry & Molecular Biology

Naked Mole-Rat, a Rodent with an Apolipoprotein A-I Dimer

Don L. Puppione et al.

Summary: The protein encoded by the naked mole-rat apoA-I gene has a cysteine at residue 28, which enables it to form homodimers, displaying a unique sequence compared to other mammalian apoA-I proteins.

LIPIDS (2021)

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Article Biochemical Research Methods

Blockade of High-Fat Diet Proteomic Phenotypes Using Exercise as Prevention or Treatment

Sergio F. Martinez-Huenchullan et al.

Summary: The study revealed that a high-fat diet has significant effects on the plasma proteome, but exercise can partially reverse these effects, with better results as a preventative measure. Endurance running slightly outperformed high-intensity interval training, but both showed similar reversal effects on protein abundance modulated by the high-fat diet.

MOLECULAR & CELLULAR PROTEOMICS (2021)

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Review Endocrinology & Metabolism

Global pandemics interconnected - obesity, impaired metabolic health and COVID-19

Norbert Stefan et al.

Summary: Obesity and impaired metabolic health are established risk factors for NCDs such as type 2 diabetes mellitus, cardiovascular disease, neurodegenerative diseases, cancer, and MAFLD, and have been linked to an increased risk of severe COVID-19. Specifically, visceral obesity and characteristics of impaired metabolic health are associated with a high risk of severe COVID-19.

NATURE REVIEWS ENDOCRINOLOGY (2021)

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Article Multidisciplinary Sciences

Altered high-density lipoprotein composition and functions during severe COVID-19

Floran Begue et al.

Summary: The study showed significant changes in HDL proteome and decreased functionality in severe COVID-19 patients.

SCIENTIFIC REPORTS (2021)

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Letter Medicine, General & Internal

Retail Alcohol and Tobacco Sales During COVID-19

Brian P. Lee et al.

ANNALS OF INTERNAL MEDICINE (2021)

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Article Hematology

The relationship between serum erythropoietin, hepcidin, and haptoglobin levels with disease severity and other biochemical values in patients with COVID-19

Sema Yagci et al.

Summary: Our study found that serum iron and hepcidin levels decreased in patients diagnosed with COVID-19, while EPO and Hpt levels were significantly lower in critical and deceased patient groups. This is the first study examining EPO and Hpt levels in patients diagnosed with COVID-19.

INTERNATIONAL JOURNAL OF LABORATORY HEMATOLOGY (2021)

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Article Medicine, General & Internal

A Randomized, Controlled Trial of the Pan-PPAR Agonist Lanifibranor in NASH

Sven M. Francque et al.

Summary: In a randomized trial, the pan-PPAR agonist Lanifibranor showed significant improvement in histologic features of NASH at a dose of 1200 mg. However, adverse events such as weight gain, anemia, peripheral edema, diarrhea, and nausea were more common with Lanifibranor compared to placebo.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

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Article Biochemistry & Molecular Biology

Association of serum HDL-cholesterol and apolipoprotein A1 levels with risk of severe SARS-CoV-2 infection

James R. Hilser et al.

Summary: Individuals with features of metabolic syndrome are more susceptible to severe COVID-19 caused by SARS-CoV-2. Higher levels of serum HDL-cholesterol and apolipoprotein A1 may reduce the risk of SARS-CoV-2 infection, but genetically elevated HDL-cholesterol levels are not associated with SARS-CoV-2 infection.

JOURNAL OF LIPID RESEARCH (2021)

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Article Multidisciplinary Sciences

The MC4R p.Ile269Asn mutation confers a high risk for type 2 diabetes in the Mexican population via obesity dependent and independent effects

Miguel Vazquez-Moreno et al.

Summary: The MC4R p.Ile269Asn mutation is associated with an increased risk of T2D in Mexican adults, even after adjusting for BMI. Mediation analysis showed that BMI accounts for 22.7% of the association between the mutation and T2D risk.

SCIENTIFIC REPORTS (2021)

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Review Public, Environmental & Occupational Health

Prognostic value of apolipoproteins in COVID-19 patients: A systematic review and meta-analysis

Juan R. Ulloque-Badaracco et al.

Summary: The study found that low levels of plasma apolipoprotein A1 (ApoA1) and apolipoprotein B (ApoB) in COVID-19 patients are associated with increased risk of developing severe disease, while the ApoB/ApoA1 ratio does not show a significant association with severity. Additionally, low ApoA1 levels are linked to higher all-cause mortality rates.

TRAVEL MEDICINE AND INFECTIOUS DISEASE (2021)

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Article Physiology

Mechanism-Based Biomarker Prediction for Low-Grade Inflammation in Liver and Adipose Tissue

Jolanda H. M. van Bilsen et al.

Summary: Metabolic disorders such as obesity and type 2 diabetes have a significant impact on global health, with tissue-specific chronic low-grade inflammation playing a key role in complications. An in silico approach was used to select candidate biomarkers for tissue-specific inflammation, with potential for studying future therapeutic/lifestyle interventions for metabolic inflammatory complications.

FRONTIERS IN PHYSIOLOGY (2021)

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Review Immunology

Alpha-2-Macroglobulin in Inflammation, Immunity and Infections

Jennifer Vandooren et al.

Summary: Alpha-2-macroglobulin is known for its role as a broad-spectrum protease inhibitor and has additional functions such as regulating proteolysis, promoting cell migration, and binding cytokines, especially crucial in immune-cell function. This review provides an overview of all functions of Alpha-2-macroglobulin in the context of inflammation, immunity, and infections.

FRONTIERS IN IMMUNOLOGY (2021)

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Article Multidisciplinary Sciences

Baseline cardiometabolic profiles and SARS-CoV-2 infection in the UK Biobank

Ryan J. Scalsky et al.

Summary: This study found that higher BMI, type II diabetes, and HbA1c levels were associated with increased odds of testing positive for SARS-CoV-2, while elevated HDL-C and ApoA-I levels were associated with reduced odds. The effects of BMI, type II diabetes, and HbA1c levels may be mediated in part through regulation of HDL-C levels.

PLOS ONE (2021)

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Article Gastroenterology & Hepatology

Prospective external validation of a new non-invasive test for the diagnosis of non-alcoholic steatohepatitis in patients with type 2 diabetes

Thierry Poynard et al.

Summary: The study aimed to externally validate the performance of Nash-FibroTest panel in assessing the severity of fibrosis stages, NASH grades, and steatosis grades in patients with type 2 diabetes. The diagnostic performance of each component of the panel was found to be significant, providing non-invasive diagnosis of fibrosis stages, NASH grades, and steatosis grades from a single blood sample.

ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2021)

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Article Surgery

The impact of bariatric surgery on nonalcoholic fatty liver disease as measured using non-invasive tests

Carmit Netanel et al.

Summary: This study evaluated the effects of sleeve gastrectomy on morbid obesity and NAFLD, and found significant improvements in body mass index, triglycerides, ALT, diabetes markers, and adiponectin one year post-surgery. Non-invasive measures also showed significant improvements in steatosis and steatohepatitis, while fibrosis levels remained stable over time.

AMERICAN JOURNAL OF SURGERY (2021)

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Article Medicine, Research & Experimental

High-resolution serum proteome trajectories in COVID-19 reveal patient-specific seroconversion

Philipp E. Geyer et al.

Summary: The study utilized proteomics to analyze serum proteomes of COVID-19 patients and controls, finding significant changes in 26% of proteins in COVID-19 patients, including proteins related to the immune system and coagulation mechanisms. The research also revealed correlations between SARS-CoV-2 antibodies and immunoglobulin regions through mass spectrometry-based proteomics, showing potential pathophysiological relevance.

EMBO MOLECULAR MEDICINE (2021)

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Article Multidisciplinary Sciences

Enterically derived high-density lipoprotein restrains liver injury through the portal vein

Yong-Hyun Han et al.

Summary: Research shows that HDL3 derived from the intestine can enter the bloodstream through the portal vein, preventing the binding of lipopolysaccharide and inflammatory activation of liver macrophages, thereby protecting the liver from injury caused by gut-derived LPS.

SCIENCE (2021)

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Article Multidisciplinary Sciences

Impact of overlapping risks of type 2 diabetes and obesity on coronavirus disease severity in the United States

Wataru Ando et al.

Summary: This study evaluated the impact of type 2 diabetes (T2D) and obesity on the hospitalization and critical care risks for COVID-19 patients. The results showed that T2D, obesity, and male sex were significantly associated with an increased risk of COVID-19 hospitalization, with complications from diabetes and obesity also increasing the risks of hospitalization and critical care for COVID-19 patients.

SCIENTIFIC REPORTS (2021)

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Article Medicine, General & Internal

Remission of Diabetes Following Bariatric Surgery: Plasma Proteomic Profiles

Maria Insenser et al.

Summary: The study found that some severely obese patients with type 2 diabetes can restore glucose tolerance after weight-loss surgery. Remission of diabetes after surgery is associated with significant changes in specific proteins in the plasma, which are related to acute-phase response, fibrinolysis, platelet degranulation, and blood coagulation.

JOURNAL OF CLINICAL MEDICINE (2021)

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Article Immunology

Systemic Inflammation and Microbial Translocation Are Characteristic Features of SARS-CoV-2-Related Multisystem Inflammatory Syndrome in Children

Nathella Pavan Kumar et al.

Summary: MIS-C children showed significantly higher levels of acute phase proteins and microbial translocation markers, indicating a role of systemic inflammation in the pathogenesis of SARS-CoV-2 infection in children. Principal component analysis using these markers could differentiate MIS-C and COVID-19 from other children, providing insights into different presentations of the disease.

OPEN FORUM INFECTIOUS DISEASES (2021)

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Article Gastroenterology & Hepatology

Impact of COVID-19 in Liver Disease Progression

Miguel Angel Martinez et al.

Summary: The novel coronavirus SARS-CoV-2 has caused the global COVID-19 pandemic in a short period of time, with implications for individuals with underlying chronic liver disease who may face increased risk of adverse outcomes and liver damage.

HEPATOLOGY COMMUNICATIONS (2021)

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Article Endocrinology & Metabolism

Performance of Plasma Biomarkers and Diagnostic Panels for Nonalcoholic Steatohepatitis and Advanced Fibrosis in Patients With Type 2 Diabetes

Fernando Bril et al.

DIABETES CARE (2020)

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Article Gastroenterology & Hepatology

Performance of liver biomarkers, in patients at risk of nonalcoholic steato-hepatitis, according to presence of type-2 diabetes

Thierry Poynard et al.

EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY (2020)

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Article Gastroenterology & Hepatology

HDL-related biomarkers are robust predictors of survival in patients with chronic liver failure

Markus Trieb et al.

JOURNAL OF HEPATOLOGY (2020)

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Letter Infectious Diseases

An interactive web-based dashboard to track COVID-19 in real time

Ensheng Dong et al.

LANCET INFECTIOUS DISEASES (2020)

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Article Endocrinology & Metabolism

Causal Association of Haptoglobin With Obesity in Mexican Children: A Mendelian Randomization Study

Miguel Vazquez-Moreno et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2020)

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Editorial Material Endocrinology & Metabolism

Practical recommendations for the management of diabetes in patients with COVID-19

Stefan R. Bornstein et al.

LANCET DIABETES & ENDOCRINOLOGY (2020)

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Article Oncology

Predictive Modeling of Thoracic Radiotherapy Toxicity and the Potential Role of Serum Alpha-2-Macroglobulin

Donata von Reibnitz et al.

FRONTIERS IN ONCOLOGY (2020)

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Article Gastroenterology & Hepatology

A blood-based biomarker panel (NIS4) for non-invasive diagnosis of non-alcoholic steatohepatitis and liver fibrosis: a prospective derivation and global validation study

Stephen A. Harrison et al.

LANCET GASTROENTEROLOGY & HEPATOLOGY (2020)

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Review Pharmacology & Pharmacy

Interaction between high-density lipoproteins and inflammation: Function matters more than concentration!

Sumra Nazir et al.

ADVANCED DRUG DELIVERY REVIEWS (2020)

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A wealth of genotype-specific proteoforms fine-tunes hemoglobin scavenging by haptoglobin

Sem Tamara et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

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Article Medicine, General & Internal

Non-alcoholic fatty liver disease and type 2 diabetes mellitus: issues of the liver fibrosis diagnostics

A. Anisonyan et al.

TERAPEVTICHESKII ARKHIV (2020)

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Article Multidisciplinary Sciences

Performance of serum apolipoprotein-A1 as a sentinel of Covid-19

Thierry Poynard et al.

PLOS ONE (2020)

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DIPPER, a spatiotemporal proteomics atlas of human intervertebral discs for exploring ageing and degeneration dynamics

Vivian Tam et al.

ELIFE (2020)

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Article Endocrinology & Metabolism

Association of the genetic variant rs2000999 with haptoglobin and diabetic macrovascular diseases in Chinese patients with type 2 diabetes

Shiyun Wang et al.

JOURNAL OF DIABETES AND ITS COMPLICATIONS (2019)

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Article Multidisciplinary Sciences

Non-alcoholic fatty liver disease is associated with dysregulated bile acid synthesis and diarrhea: A prospective observational study

Richard N. Appleby et al.

PLOS ONE (2019)

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Article Medicine, General & Internal

Effects of Caloric Restriction with Protein Supplementation on Plasma Protein Profiles in Middle-Aged Women with Metabolic Syndrome-A Preliminary Open Study

Chia-Yu Chang et al.

JOURNAL OF CLINICAL MEDICINE (2019)

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Article Multidisciplinary Sciences

Molecular form and concentration of serum α2-macroglobulin in diabetes

Sonomi Yoshino et al.

SCIENTIFIC REPORTS (2019)

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Article Gastroenterology & Hepatology

Validation of Serum Test for Advanced Liver Fibrosis in Patients With Nonalcoholic Steatohepatitis

Rohit Loomba et al.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2019)

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Article Biochemistry & Molecular Biology

Type 2 diabetes-related proteins derived from an in vitro model of inflamed fat tissue

Jean Paul ten Klooster et al.

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2018)

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Review Gastroenterology & Hepatology

Non-invasive assessment of non-alcoholic fatty liver disease: Clinical prediction rules and blood-based biomarkers

Eduardo Vilar-Gomez et al.

JOURNAL OF HEPATOLOGY (2018)

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Article Oncology

Increased jejunal permeability in human obesity is revealed by a lipid challenge and is linked to inflammation and type 2 diabetes

Laurent Genser et al.

JOURNAL OF PATHOLOGY (2018)

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Article Gastroenterology & Hepatology

Long-term prognostic value of the FibroTest in patients with non-alcoholic fatty liver disease, compared to chronic hepatitis C, B, and alcoholic liver disease

Mona Munteanu et al.

ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2018)

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Article Gastroenterology & Hepatology

A novel noninvasive diagnostic method for nonalcoholic steatohepatitis using two glycobiomarkers

Yoshihiro Kamada et al.

HEPATOLOGY (2015)

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Article Gastroenterology & Hepatology

The development of a clinical score for the prediction of nonalcoholic steatohepatitis in patients with nonalcoholic fatty liver disease using routine parameters

Li Chunming et al.

TURKISH JOURNAL OF GASTROENTEROLOGY (2015)

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Article Medicine, General & Internal

Awareness of the severity of liver disease re-examined using software-combined biomarkers of liver fibrosis and necroinflammatory activity

Thierry Poynard et al.

BMJ OPEN (2015)

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Article Endocrinology & Metabolism

Effects of diabetes definition on global surveillance of diabetes prevalence and diagnosis: a pooled analysis of 96 population-based studies with 331288 participants

Goodarz Danaei et al.

LANCET DIABETES & ENDOCRINOLOGY (2015)

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Article Gastroenterology & Hepatology

Simple biochemical parameters and a novel score correlate with absence of fibrosis in patients with nonalcoholic fatty liver disease

Akash Shukla et al.

INDIAN JOURNAL OF GASTROENTEROLOGY (2015)

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Article Gastroenterology & Hepatology

Prognostic value of liver fibrosis and steatosis biomarkers in type-2 diabetes and dyslipidaemia

H. Perazzo et al.

ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2014)

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Article Gastroenterology & Hepatology

Utility and Appropriateness of the Fatty Liver Inhibition of Progression (FLIP) Algorithm and Steatosis, Activity, and Fibrosis (SAF) Score in the Evaluation of Biopsies of Nonalcoholic Fatty Liver Disease

Pierre Bedossa

HEPATOLOGY (2014)

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Effects of dietary components on high-density lipoprotein measures in a cohort of 1,566 participants

Daniel Seung Kim et al.

NUTRITION & METABOLISM (2014)

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Review Cell Biology

Alpha-2-macroglobulin: A physiological guardian

Ahmed A. Rehman et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2013)

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Review Medicine, Research & Experimental

The role of Haptoglobin and its related protein, Zonulin, in inflammatory bowel disease

Tim Vanuytsel et al.

TISSUE BARRIERS (2013)

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Article Gastroenterology & Hepatology

Screening for liver fibrosis by using FibroScan® and FibroTest in patients with diabetes

Victor de Ledinghen et al.

DIGESTIVE AND LIVER DISEASE (2012)

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Article Gastroenterology & Hepatology

Histopathological algorithm and scoring system for evaluation of liver lesions in morbidly obese patients

Pierre Bedossa et al.

HEPATOLOGY (2012)

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Article Gastroenterology & Hepatology

Applicability and precautions of use of liver injury biomarker FibroTest. A reappraisal at 7 years of age

Thierry Poynard et al.

BMC GASTROENTEROLOGY (2011)

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Article Medicine, General & Internal

Haptoglobin and risk of myocardial infarction, stroke, and congestive heart failure in 342,125 men and women in the Apolipoprotein MOrtality RISk study (AMORIS)

Ingar Holme et al.

ANNALS OF MEDICINE (2009)

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Article Gastroenterology & Hepatology

Screening for liver fibrosis by using a noninvasive biomarker in patients with diabetes

Sophie Jacqueminet et al.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2008)

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Article Biochemical Research Methods

On the search for glycated lipoprotein ApoA-I in the plasma of diabetic and nephropathic patients

Annunziata Lapolla et al.

JOURNAL OF MASS SPECTROMETRY (2008)

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Article Medical Laboratory Technology

Reference distributions for apolipoproteins Al and B and the apolipoprotein B/Al ratios: A practical and clinically relevant approach in a large cohort

Robert F. Ritchie et al.

JOURNAL OF CLINICAL LABORATORY ANALYSIS (2006)

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Article Gastroenterology & Hepatology

Design and validation of a histological scoring system for nonalcoholic fatty liver disease

DE Kleiner et al.

HEPATOLOGY (2005)

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Article Biochemistry & Molecular Biology

Haptoglobin release by human adipose tissue in primary culture

JN Fain et al.

JOURNAL OF LIPID RESEARCH (2004)

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Article Medical Laboratory Technology

Reference distributions for alpha(2)-macroglobulin: A comparison of a large cohort to the world's literature

RF Ritchie et al.

JOURNAL OF CLINICAL LABORATORY ANALYSIS (2004)

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Article Nutrition & Dietetics

Relationship between alpha-2-macroglobulin, anthropometric parameters and lipid profiles in Thai overweight and obese in Bangkok

R Tungtrongchitr et al.

NUTRITION RESEARCH (2003)

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Article Urology & Nephrology

Nephrotic proteinuria has no net effect on total body protein synthesis:: Measurements with 13C valine

MGM de Sain-van der Velden et al.

AMERICAN JOURNAL OF KIDNEY DISEASES (2000)

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Clinical Interest of Serum Alpha-2 Macroglobulin, Apolipoprotein A1, and Haptoglobin in Patients with Non-Alcoholic Fatty Liver Disease, with and without Type 2 Diabetes, before or during COVID-19

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