A Review of the Recent Development in the Synthesis and Biological Evaluations of Pyrazole Derivatives

Pyrazoles are five-membered heterocyclic compounds that contain nitrogen. They are an important class of compounds for drug development; thus, they have attracted much attention. In the meantime, pyrazole derivatives have been synthesized as target structures and have demonstrated numerous biological activities such as antituberculosis, antimicrobial, antifungal, and anti-inflammatory. This review summarizes the results of published research on pyrazole derivatives synthesis and biological activities. The published research works on pyrazole derivatives synthesis and biological activities between January 2018 and December 2021 were retrieved from the Scopus database and reviewed accordingly.

Automated summary

Pyrazoles are nitrogen-containing five-membered heterocyclic compounds that are important for drug development and exhibit diverse biological activities. This review summarizes published research on the synthesis and biological activities of pyrazole derivatives.