Related references
Note: Only part of the references are listed.Targeting p53 for the treatment of cancer
Michael J. Duffy et al.
SEMINARS IN CANCER BIOLOGY (2022)
A Phase II Study of the Efficacy and Safety of Oral Selinexor in Recurrent Glioblastoma
Andrew B. Lassman et al.
CLINICAL CANCER RESEARCH (2022)
Thiabendazole Inhibits Glioblastoma Cell Proliferation and Invasion Targeting Mini-chromosome Maintenance Protein 2
Yaotian Hu et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2022)
From GWAS to drug screening: repurposing antipsychotics for glioblastoma
Wei-Zhi Lin et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2022)
Emerging Roles of the Tumor Suppressor p53 in Metabolism
Lili Yu et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2022)
Benzimidazoles induce concurrent apoptosis and pyroptosis of human glioblastoma cells via arresting cell cycle
Li-wen Ren et al.
ACTA PHARMACOLOGICA SINICA (2022)
Influence of supramarginal resection on survival outcomes after gross-total resection of IDH-wild-type glioblastoma
Tito Vivas-Buitrago et al.
JOURNAL OF NEUROSURGERY (2022)
Combination of ALA-induced fluorescence-guided resection and intraoperative open photodynamic therapy for recurrent glioblastoma: case series on a promising dual strategy for local tumor control
Stephanie Schipmann et al.
JOURNAL OF NEUROSURGERY (2021)
p53 signaling in cancer progression and therapy
Hany E. Marei et al.
CANCER CELL INTERNATIONAL (2021)
Oncogenic role of karyopherin α2 (KPNA2) in human tumors: A pan-cancer analysis
Yiming Sun et al.
COMPUTERS IN BIOLOGY AND MEDICINE (2021)
The p53 Pathway and Metabolism: The Tree That Hides the Forest
Airelle Lahalle et al.
CANCERS (2021)
CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2014-2018
Quinn T. Ostrom et al.
NEURO-ONCOLOGY (2021)
The novel BET inhibitor UM-002 reduces glioblastoma cell proliferation and invasion
Anna M. Jermakowicz et al.
SCIENTIFIC REPORTS (2021)
The Role of MicroRNAs in Therapeutic Resistance of Malignant Primary Brain Tumors
Ilgiz Gareev et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)
Anticancer Mechanism of Curcumin on Human Glioblastoma
Shu Chyi Wong et al.
NUTRIENTS (2021)
A Systematic Review of Glioblastoma-Targeted Therapies in Phases II, III, IV Clinical Trials
Elisabete Cruz Da Silva et al.
CANCERS (2021)
Antitumor Effects of 5-Aminolevulinic Acid on Human Malignant Glioblastoma Cells
Mohammad Jalili-Nik et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
MDM2/X Inhibitors as Radiosensitizers for Glioblastoma Targeted Therapy
Xanthene Miles et al.
FRONTIERS IN ONCOLOGY (2021)
Rationale and Clinical Implications of Fluorescein-Guided Supramarginal Resection in Newly Diagnosed High-Grade Glioma
Linda M. Wang et al.
FRONTIERS IN ONCOLOGY (2021)
The Functions of BET Proteins in Gene Transcription of Biology and Diseases
Ka Lung Cheung et al.
FRONTIERS IN MOLECULAR BIOSCIENCES (2021)
Therapeutic potential of parkin as a tumor suppressor via transcriptional control of cyclins in glioblastoma cell and animal models
Lila Rouland et al.
THERANOSTICS (2021)
PARP-mediated PARylation of MGMT is critical to promote repair of temozolomide-induced O6-methylguanine DNA damage in glioblastoma
Shaofang Wu et al.
NEURO-ONCOLOGY (2021)
The Dopamine D2 Receptor Contributes to the Spheroid Formation Behavior of U87 Glioblastoma Cells
Jillian S. Weissenrieder et al.
PHARMACOLOGY (2020)
How did lomustine become standard of care in recurrent glioblastoma?
Michael Weller et al.
CANCER TREATMENT REVIEWS (2020)
Targeting nuclear import and export in hematological malignancies
Boaz Nachmias et al.
LEUKEMIA (2020)
Longer-term (≥2 years) survival in patients with glioblastoma in population-based studies pre- and post-2005: a systematic review and meta-analysis
Michael T. C. Poon et al.
SCIENTIFIC REPORTS (2020)
Ion Channels as Therapeutic Targets in High Grade Gliomas
Michaela Griffin et al.
CANCERS (2020)
A Glance of p53 Functions in Brain Development, Neural Stem Cells, and Brain Cancer
Yuqing Xiong et al.
BIOLOGY-BASEL (2020)
Tectorigenin Inhibits Glioblastoma Proliferation by G0/G1 Cell Cycle Arrest
Liang-Tsai Yeh et al.
MEDICINA-LITHUANIA (2020)
Haloperidol Induced Cell Cycle Arrest and Apoptosis in Glioblastoma Cells
Fotios Papadopoulos et al.
BIOMEDICINES (2020)
Lomustine-temozolomide combination therapy versus standard temozolomide therapy in patients with newly diagnosed glioblastoma with methylated MGMT promoter (CeTeG/NOA-09): a randomised, open-label, phase 3 trial
Ulrich Herrlinger et al.
LANCET (2019)
Alkylaminophenol Induces G1/S Phase Cell Cycle Arrest in Glioblastoma Cells Through p53 and Cyclin-Dependent Kinase Signaling Pathway
Phuong Doan et al.
FRONTIERS IN PHARMACOLOGY (2019)
A Phase 0 Trial of Ribociclib in Recurrent Glioblastoma Patients Incorporating a Tumor Pharmacodynamic- and Pharmacokinetic-Guided Expansion Cohort
An-Chi Tien et al.
CLINICAL CANCER RESEARCH (2019)
Combining the DNA Repair Inhibitor Dbait With Radiotherapy for the Treatment of High Grade Glioma: Efficacy and Protein Biomarkers of Resistance in Preclinical Models
Julian Biau et al.
FRONTIERS IN ONCOLOGY (2019)
Bromodomain inhibitor jq1 induces cell cycle arrest and apoptosis of glioma stem cells through the VEGF/PI3K/AKT signaling pathway
Naiyan Wen et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2019)
Molecular targeted therapy of glioblastoma
Emilie Le Rhun et al.
CANCER TREATMENT REVIEWS (2019)
Karyopherin α2-dependent import of E2F1 and TFDP1 maintains protumorigenic stathmin expression in liver cancer
Elisabeth Drucker et al.
CELL COMMUNICATION AND SIGNALING (2019)
Putting the brakes on the cell cycle: mechanisms of cellular growth arrest
Lindsey R. Pack et al.
CURRENT OPINION IN CELL BIOLOGY (2019)
YB-1 modulates the drug resistance of glioma cells by activation of MDM2/p53 pathway
Hui Tong et al.
DRUG DESIGN DEVELOPMENT AND THERAPY (2019)
The Molecular Mechanisms of Plant-Derived Compounds Targeting Brain Cancer
Hueng-Chuen Fan et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Cyclin D/CDK4/6 activity controls G1 length in mammalian cells
Peng Dong et al.
PLOS ONE (2018)
Stochastic Endogenous Replication Stress Causes ATR-Triggered Fluctuations in CDK2 Activity that Dynamically Adjust Global DNA Synthesis Rates
Leighton H. Daigh et al.
CELL SYSTEMS (2018)
CDK4/6 Inhibition in Cancer: Beyond Cell Cycle Arrest
Shom Goel et al.
TRENDS IN CELL BIOLOGY (2018)
Silencing of the nucleocytoplasmic shuttling protein karyopherin a2 promotes cell-cycle arrest and apoptosis in glioblastoma multiforme
Ramon Martinez-Olivera et al.
Oncotarget (2018)
Flubendazole inhibits glioma proliferation by G2/M cell cycle arrest and pro-apoptosis
Xumin Zhou et al.
CELL DEATH DISCOVERY (2018)
Cell cycle arrest through indirect transcriptional repression by p53: I have a DREAM
Kurt Engeland
CELL DEATH AND DIFFERENTIATION (2018)
The BCL-2 arbiters of apoptosis and their growing role as cancer targets
Jerry M. Adams et al.
CELL DEATH AND DIFFERENTIATION (2018)
Effect of Tumor-Treating Fields Plus Maintenance Temozolomide vs Maintenance Temozolomide Alone on Survival in Patients With Glioblastoma A Randomized Clinical Trial
Roger Stupp et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2017)
Resveratrol targeting of AKT and p53 in glioblastoma and glioblastoma stem-like cells to suppress growth and infiltration
Paul A. Clark et al.
JOURNAL OF NEUROSURGERY (2017)
Competing memories of mitogen and p53 signalling control cell-cycle entry
Hee Won Yang et al.
NATURE (2017)
Moschamine inhibits proliferation of glioblastoma cells via cell cycle arrest and apoptosis
George A. Alexiou et al.
TUMOR BIOLOGY (2017)
A competing endogenous RNA network identifies novel mRNA, miRNA and lncRNA markers for the prognosis of diabetic pancreatic cancer
Kanyu Yao et al.
TUMOR BIOLOGY (2017)
DNA damage during S-phase mediates the proliferation-quiescence decision in the subsequent G1 via p21 expression
Alexis R. Barr et al.
NATURE COMMUNICATIONS (2017)
MicroRNA-141-3p promotes glioma cell growth and temozolomide resistance by directly targeting p53
Xu Zhou et al.
ONCOTARGET (2017)
Controlling Depth of Cellular Quiescence by an Rb-E2F Network Switch
Jungeun Sarah Kwon et al.
CELL REPORTS (2017)
Endogenous Replication Stress in Mother Cells Leads to Quiescence of Daughter Cells
Mansi Arora et al.
CELL REPORTS (2017)
Ion channel expression patterns in glioblastoma stem cells with functional and therapeutic implications for malignancy
Julia Pollak et al.
PLOS ONE (2017)
Tumor treating fields: a novel and effective therapy for glioblastoma: mechanism, efficacy, safety and future perspectives
Ping Zhu et al.
CHINESE CLINICAL ONCOLOGY (2017)
Preclinical Efficacy of the MDM2 Inhibitor RG7112 in MDM2-Amplified and TP53 Wild-type Glioblastomas
Maite Verreault et al.
CLINICAL CANCER RESEARCH (2016)
Nuclear factor-κB in glioblastoma: insights into regulators and targeted therapy
Kirk E. Cahill et al.
NEURO-ONCOLOGY (2016)
MIF Maintains the Tumorigenic Capacity of Brain Tumor-Initiating Cells by Directly Inhibiting p53
Raita Fukaya et al.
CANCER RESEARCH (2016)
Irreversible APCCdh1 Inactivation Underlies the Point of No Return for Cell-Cycle Entry
Steven D. Cappell et al.
CELL (2016)
Efficacy and Safety of Abemaciclib, an Inhibitor of CDK4 and CDK6, for Patients with Breast Cancer, Non-Small Cell Lung Cancer, and Other Solid Tumors
Amita Patnaik et al.
CANCER DISCOVERY (2016)
Bromodomain Inhibitor Review: Bromodomain and Extra-terminal Family Protein Inhibitors as a Potential New Therapy in Central Nervous System Tumors
Elizabeth Wadhwa et al.
CUREUS JOURNAL OF MEDICAL SCIENCE (2016)
Cellular Pathways in Response to Ionizing Radiation and Their Targetability for Tumor Radiosensitization
Patrick Maier et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)
Tumor Treating Fields Perturb the Localization of Septins and Cause Aberrant Mitotic Exit
Nidhi Gera et al.
PLOS ONE (2015)
Gene expressions of TRP channels in glioblastoma multiforme and relation with survival
M. Alptekin et al.
TUMOR BIOLOGY (2015)
Ion channel gene expression predicts survival in glioma patients
Rong Wang et al.
SCIENTIFIC REPORTS (2015)
Preclinical antitumor efficacy of selective exportin 1 inhibitors in glioblastoma
Adam L. Green et al.
NEURO-ONCOLOGY (2015)
TERT promoter mutations: a novel independent prognostic factor in primary glioblastomas
Matthias Simon et al.
NEURO-ONCOLOGY (2015)
TP53 Promoter Methylation in Primary Glioblastoma: Relationship with TP53 mRNA and Protein Expression and Mutation Status
Dorota Jesionek-Kupnicka et al.
DNA AND CELL BIOLOGY (2014)
Nucleo-cytoplasmic transport as a therapeutic target of cancer
Giovanni Luca Gravina et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2014)
Karyopherin a2 and chromosome region maintenance protein 1 expression in meningiomas: novel biomarkers for recurrence and malignant progression
Konstantinos Gousias et al.
JOURNAL OF NEURO-ONCOLOGY (2014)
A novel tumor-promoting role for nuclear factor IA in glioblastomas is mediated through negative regulation of p53, p21, and PAI1
Jun Sung Lee et al.
NEURO-ONCOLOGY (2014)
Glioma tumor grade correlates with parkin depletion in mutant p53-linked tumors and results from loss of function of p53 transcriptional activity
J. Viotti et al.
ONCOGENE (2014)
Herg K+ Channel-Dependent Apoptosis and Cell Cycle Arrest in Human Glioblastoma Cells
Ingo Staudacher et al.
PLOS ONE (2014)
Targeting PI3K/Akt/mTOR signaling in cancer
Camillo Porta et al.
FRONTIERS IN ONCOLOGY (2014)
The Proliferation-Quiescence Decision Is Controlled by a Bifurcation in CDK2 Activity at Mitotic Exit
Sabrina L. Spencer et al.
CELL (2013)
The Somatic Genomic Landscape of Glioblastoma
Cameron W. Brennan et al.
CELL (2013)
Human Glioblastoma Multiforme: p53 Reactivation by a Novel MDM2 Inhibitor
Barbara Costa et al.
PLOS ONE (2013)
TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal
Patrick J. Killela et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
p38γ overexpression in gliomas and its role in proliferation and apoptosis
Kui Yang et al.
SCIENTIFIC REPORTS (2013)
Nuclear karyopherin a2: a novel biomarker for infiltrative astrocytomas
K. Gousias et al.
JOURNAL OF NEURO-ONCOLOGY (2012)
The curry spice curcumin selectively inhibits cancer cells growth in vitro and in preclinical model of glioblastoma
Alfeu Zanotto-Filho et al.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2012)
Targeting JNK for therapeutic depletion of stem-like glioblastoma cells
Ken-ichiro Matsuda et al.
SCIENTIFIC REPORTS (2012)
Antiparasitic mebendazole shows survival benefit in 2 preclinical models of glioblastoma multiforme
Ren-Yuan Bai et al.
NEURO-ONCOLOGY (2011)
Comparison of RBE values of high- LET α-particles for the induction of DNA-DSBs, chromosome aberrations and cell reproductive death
Nicolaas A. P. Franken et al.
RADIATION ONCOLOGY (2011)
Residual Tumor Cells Are Unique Cellular Targets in Glioblastoma
Martin Glas et al.
ANNALS OF NEUROLOGY (2010)
Deregulated signalling networks in human brain tumours
Michal Grzmil et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2010)
Loss of ATM/Chk2/p53 Pathway Components Accelerates Tumor Development and Contributes to Radiation Resistance in Gliomas
Massimo Squatrito et al.
CANCER CELL (2010)
Pharmacologic Inhibition of Cyclin-Dependent Kinases 4 and 6 Arrests the Growth of Glioblastoma Multiforme Intracranial Xenografts
Karine Michaud et al.
CANCER RESEARCH (2010)
Targeting the RB-pathway in Cancer Therapy
Erik S. Knudsen et al.
CLINICAL CANCER RESEARCH (2010)
Glioma oncoprotein Bcl2L12 inhibits the p53 tumor suppressor
Alexander H. Stegh et al.
GENES & DEVELOPMENT (2010)
The anti-cancer efficacy of curcumin scrutinized through core signaling pathways in glioblastoma
Chin-Cheng Su et al.
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2010)
Quantitative analysis of cell cycle phase durations and PC12 differentiation using fluorescent biosensors
Angela T. Hahn et al.
CELL CYCLE (2009)
Brd4 Marks Select Genes on Mitotic Chromatin and Directs Postmitotic Transcription
Anup Dey et al.
MOLECULAR BIOLOGY OF THE CELL (2009)
Visualizing spatiotemporal dynamics of multicellular cell-cycle progression
Asako Sakaue-Sawano et al.
CELL (2008)
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
L. Chin et al.
NATURE (2008)
NF-kappa B controls growth of glioblastomas/astrocytomas
Denise Smith et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2008)
Curcumin suppressed anti-apoptotic signals and activated cysteine proteases for apoptosis in human malignant glioblastoma U87MG cells
Surajit Karmakar et al.
NEUROCHEMICAL RESEARCH (2007)
Aberrant constitutive activation of nuclear factor κB in glioblastoma multiforme drives invasive phenotype
Baisakhi Raychaudhuri et al.
JOURNAL OF NEURO-ONCOLOGY (2007)
Bcl2L12 inhibits post-mitochondrial apoptosis signaling in glioblastoma
Alexander H. Stegh et al.
GENES & DEVELOPMENT (2007)
Apoptosis: A review of programmed cell death
Susan Elmore
TOXICOLOGIC PATHOLOGY (2007)
Nucleocytoplasmic shuttling of the retinoblastoma tumor suppressor protein via Cdk phosphorylation-dependent nuclear export
Wan Jiao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Overexpression of EagI potassium channels in clinical tumours
Bernhard Hemmerlein et al.
MOLECULAR CANCER (2006)
Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma: a randomised controlled multicentre phase III trial
W Stummer et al.
LANCET ONCOLOGY (2006)
Causes of cancer in the world: comparative risk assessment of nine behavioural and environmental risk factors
G Danaei et al.
LANCET (2005)
Detection of somatic TP53 splice site mutations in diffuse astrocytomas
M Uno et al.
CANCER LETTERS (2005)
Deregulated E2F activity induces hyperplasia and senescence-like features in the mouse pituitary gland
EL Denchi et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
MGMT gene silencing and benefit from temozolomide in glioblastoma
ME Hegi et al.
NEW ENGLAND JOURNAL OF MEDICINE (2005)
Role for calcium-activated potassium channels (BK) in growth control of human malignant glioma cells
AK Weaver et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2004)
Decision making by p53: life, death and cancer
M Oren
CELL DEATH AND DIFFERENTIATION (2003)
Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents
M Esteller et al.
NEW ENGLAND JOURNAL OF MEDICINE (2000)
Share Paper
