☆ 4.7 Article

Large-Scale SARS-CoV-2 Antigen Testing With Real-World Specimens

FRONTIERS IN PUBLIC HEALTH (2022)

Related references

Note: Only part of the references are listed.

Article Microbiology

Clinical Evaluation of BD Veritor SARS-CoV-2 Point-of-Care Test Performance Compared to PCR-Based Testing and versus the Sofia 2 SARS Antigen Point-of-Care Test

Stephen Young et al.

Summary: The BD Veritor System for Rapid Detection of SARS-CoV-2 nucleocapsid antigen showed varied performance in different DSO ranges compared to PCR testing, with PPA values below 100%. However, Veritor demonstrated high agreement with Sofia 2 in detecting SARS-CoV-2.

JOURNAL OF CLINICAL MICROBIOLOGY (2021)

Add to Collection

Article Immunology

Antigen-Based Testing but Not Real-Time Polymerase Chain Reaction Correlates With Severe Acute Respiratory Syndrome Coronavirus 2 Viral Culture

Andrew Pekosz et al.

Summary: Recent studies indicate that SARS-CoV-2 antigen testing demonstrates a higher positive predictive value in the early stages of infection and shows good consistency with culture results. This testing method can significantly aid in determining the risk of carrying infectious virus.

CLINICAL INFECTIOUS DISEASES (2021)

Add to Collection

Article Multidisciplinary Sciences

Duration and key determinants of infectious virus shedding in hospitalized patients with coronavirus disease-2019 (COVID-19)

Jeroen J. A. van Kampen et al.

Summary: The study found that the median duration of shedding infectious virus in COVID-19 patients is 8 days, dropping below 5% after 15.2 days post onset of symptoms. High viral loads are associated with infectious SARS-CoV-2 isolation, while high serum neutralizing antibody titres are associated with non-infectious SARS-CoV-2.

NATURE COMMUNICATIONS (2021)

Add to Collection

Review Public, Environmental & Occupational Health

How to detect and reduce potential sources of biases in studies of SARS-CoV-2 and COVID-19

Emma K. Accorsi et al.

Summary: In response to the COVID-19 pandemic, public health scientists have produced a large body of literature, but observational studies may be biased due to confounding, selection bias, and measurement error. To accurately evaluate these studies and guide future research design, attention needs to be paid to and solutions proposed for potential biases.

EUROPEAN JOURNAL OF EPIDEMIOLOGY (2021)

Add to Collection

Article Microbiology

Factors that Influence the Reported Sensitivity of Rapid Antigen Testing for SARS-CoV-2

Valentin Parvu et al.

Summary: This systematic review evaluates the diagnostic accuracy of SARS-CoV-2 antigen detection in COVID-19 symptomatic and asymptomatic individuals and summarizes antigen test sensitivity using meta-regression.

FRONTIERS IN MICROBIOLOGY (2021)

Add to Collection

Article Multidisciplinary Sciences

Increased mortality in community-tested cases of SARS-CoV-2 lineage B.1.1.7

Nicholas G. Davies et al.

Summary: Studies have shown that the SARS-CoV-2 B.1.1.7 lineage is more transmissible and may cause more severe illness compared to pre-existing variants.

NATURE (2021)

Add to Collection

Article Medicine, General & Internal

Vaccine Breakthrough Infections with SARS-CoV-2 Variants

Ezgi Hacisuleyman et al.

Summary: Despite evidence of vaccine efficacy, two fully vaccinated individuals developed mild symptoms of Covid-19 and were infected with variants of SARS-CoV-2. Sequencing of the virus isolates revealed novel mutations, highlighting the potential risk of illness post-vaccination and subsequent infection with variant virus. Efforts to prevent, diagnose, and characterize variants in vaccinated individuals are crucial.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

Add to Collection

Article Microbiology

Multicenter Postimplementation Assessment of the Positive Predictive Value of SARS-CoV-2 Antigen-Based Point-of-Care Tests Used for Screening of Asymptomatic Continuing Care Staff

Jamil N. Kanji et al.

Summary: Frequent screening of SARS-CoV-2 among asymptomatic healthcare workers in continuing care facilities in AB, Canada using antigen-based point-of-care tests showed low detection rates and high false-positive detection rates, indicating the need for careful consideration of the benefits and risks of APOCT programs before implementation.

JOURNAL OF CLINICAL MICROBIOLOGY (2021)

Add to Collection

Article Microbiology

A Real-World Comparison of SARS-CoV-2 Rapid Antigen Testing versus PCR Testing in Florida

Lao-Tzu Allan-Blitz et al.

Summary: The positive percent agreement (PPA) of Abbott BinaxNOW COVID-19 Ag card compared to PCR was lower than previously reported, but showed a slight improvement in individuals with symptomatic presentation and a better performance in individuals with lower cycle threshold values.

JOURNAL OF CLINICAL MICROBIOLOGY (2021)

Add to Collection

Review Biochemistry & Molecular Biology

The next phase of SARS-CoV-2 surveillance: real-time molecular epidemiology

Bas B. Oude Munnink et al.

Summary: This review summarizes the current knowledge on key viral mutations and variants, emphasizing the need for a systematic approach to link global genomic surveillance with timely assessment of the phenotypic characteristics of novel variants in preparation for the next phase of the pandemic.

NATURE MEDICINE (2021)

Add to Collection

Article Multidisciplinary Sciences

Comparison of antigen- and RT-PCR-based testing strategies for detection of SARS-CoV-2 in two high-exposure settings

Jay Love et al.

Summary: Surveillance testing for infectious disease is important for combating disease transmission, with RT-PCR and antigen tests playing different roles in reducing infectious disease burden in various settings. Antigen-based surveillance testing coupled with isolation can greatly reduce disease burden at a lower economic cost compared to RT-PCR-based strategies.

PLOS ONE (2021)

Add to Collection

Article Medicine, General & Internal

Accuracy of novel antigen rapid diagnostics for SARS-CoV-2: A living systematic review and meta-analysis

Lukas E. Brummer et al.

Summary: A systematic review and meta-analysis was conducted to evaluate the clinical accuracy of commercially available Ag-RDTs for SARS-CoV-2. The study found that Ag-RDTs can detect the vast majority of infected individuals in the early phase of the disease and those with high viral load, making them valuable diagnostic tools. However, concerns were raised regarding bias across datasets and the need for standardization in conducting and reporting clinical accuracy studies for improved comparability and data utilization.

PLOS MEDICINE (2021)

Add to Collection

Article Public, Environmental & Occupational Health

Monitoring Incidence of COVID-19 Cases, Hospitalizations, and Deaths, by Vaccination Status — 13 U.S. Jurisdictions, April 4–July 17, 2021

Heather M. Scobie et al.

MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT (2021)

Add to Collection

Article Medicine, General & Internal

Severe SARS-CoV-2 Breakthrough Reinfection With Delta Variant After Recovery From Breakthrough Infection by Alpha Variant in a Fully Vaccinated Health Worker

Jayanthi Shastri et al.

Summary: The study found that despite post-vaccination immunity and immunity acquired through past infection, breakthrough infections caused by Variants of Concern can still occur in COVID-19 cases. A patient in the study experienced breakthrough infections with the Alpha variant and the Delta variant, the latter resulting in severe illness even after boosting. The source of infection was established through clinical data and genetic sequencing.

FRONTIERS IN MEDICINE (2021)

Add to Collection

Article Medicine, General & Internal

Real-life validation of the Panbio™ COVID-19 antigen rapid test (Abbott) in community-dwelling subjects with symptoms of potential SARS-CoV-2 infection

Hendrik Gremmels et al.

Summary: The antigen rapid test showed high specificity and sensitivity in community-dwelling residents in the Netherlands and Aruba, especially when using a Ct value <32 cycles as the cut-off for RT-qPCR positivity. This test could play a significant role in controlling viral spread.

ECLINICALMEDICINE (2021)

Add to Collection

Article Immunology

Antigen-Based Testing but Not Real-Time Polymerase Chain Reaction Correlates With Severe Acute Respiratory Syndrome Coronavirus 2 Viral Culture

Andrew Pekosz et al.

Summary: SARS-CoV-2 antigen testing may be positive early in the disease course, aiding in determining infectious risk, with a slightly better detection of infectious virus compared to rt-PCR.

CLINICAL INFECTIOUS DISEASES (2021)

Add to Collection

Article Infectious Diseases

Laboratory readiness and response for novel coronavirus (2019-nCoV) in expert laboratories in 30 EU/EEA countries, January 2020

Chantal B. E. M. Reusken et al.

EUROSURVEILLANCE (2020)

Add to Collection

Editorial Material Medicine, General & Internal

Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention

Zunyou Wu et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2020)

Add to Collection

Article Medicine, General & Internal

A Novel Coronavirus from Patients with Pneumonia in China, 2019

Na Zhu et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

Add to Collection

Review Chemistry, Multidisciplinary

Diagnosing COVID-19: The Disease and Tools for Detection

Buddhisha Udugama et al.

ACS NANO (2020)

Add to Collection

Editorial Material Pathology

SARS-CoV-2 Testing Trials and Tribulations

Ahmed Babiker et al.

AMERICAN JOURNAL OF CLINICAL PATHOLOGY (2020)

Add to Collection

Article Multidisciplinary Sciences

Virological assessment of hospitalized patients with COVID-2019

Roman Woelfel et al.

NATURE (2020)

Add to Collection

News Item Biotechnology & Applied Microbiology

Fast, portable tests come online to curb coronavirus pandemic

Cormac Sheridan

NATURE BIOTECHNOLOGY (2020)

Add to Collection

Article Infectious Diseases

Viral RNA load as determined by cell culture as a management tool for discharge of SARS-CoV-2 patients from infectious disease wards

Bernard La Scola et al.

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES (2020)

Add to Collection

Review Biophysics

Diagnostics for SARS-CoV-2 detection: A comprehensive review of the FDA-EUA COVID-19 testing landscape

Neeraja Ravi et al.

BIOSENSORS & BIOELECTRONICS (2020)

Add to Collection

Letter Biotechnology & Applied Microbiology

The COVID-19 XPRIZE and the need for scalable, fast, and widespread testing

Matthew J. MacKay et al.

NATURE BIOTECHNOLOGY (2020)

Add to Collection

Article Microbiology

Recommendations for use of antigenic tests in the diagnosis of acute SARS-CoV-2 infection in the second pandemic wave: attitude in different clinical settings

Francisco Javier Candel et al.

REVISTA ESPANOLA DE QUIMIOTERAPIA (2020)

Add to Collection

Article Virology

Comparison of Rapid Antigen Tests for COVID-19

Seiya Yamayoshi et al.

VIRUSES-BASEL (2020)

Add to Collection

Article Multidisciplinary Sciences

Collider bias undermines our understanding of COVID-19 disease risk and severity

Gareth J. Griffith et al.

NATURE COMMUNICATIONS (2020)

Add to Collection

Review Medicine, General & Internal

Rapid, point-of-care antigen and molecular-based tests for diagnosis of SARS-CoV-2 infection (Review)

Jacqueline Dinnes et al.

COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2020)

Add to Collection

Article Radiology, Nuclear Medicine & Medical Imaging

STARD 2015: An Updated List of Essential Items for Reporting Diagnostic Accuracy Studies

Patrick M. Bossuyt et al.

RADIOLOGY (2015)

Add to Collection

Article Pharmacology & Pharmacy

Missing Data in the Regulation of Medical Devices

Gregory Campbell et al.

JOURNAL OF BIOPHARMACEUTICAL STATISTICS (2011)

Add to Collection

© Peeref 2019-2024. All rights reserved.