Related references
Note: Only part of the references are listed.Autophagy and cancer treatment: four functional forms of autophagy and their therapeutic applications
Zhaoshi Bai et al.
JOURNAL OF ZHEJIANG UNIVERSITY-SCIENCE B (2022)
Hypoxia-Induced Cancer Cell Responses Driving Radioresistance of Hypoxic Tumors: Approaches to Targeting and Radiosensitizing
Alexander E. Kabakov et al.
CANCERS (2021)
Rac1, A Potential Target for Tumor Therapy
Jiaxin Liang et al.
FRONTIERS IN ONCOLOGY (2021)
Targeting hypoxia-inducible factor 1 (HIF-1) signaling with natural products toward cancer chemotherapy
Hiroaki Ikeda et al.
JOURNAL OF ANTIBIOTICS (2021)
YAP/TAZ: Drivers of Tumor Growth, Metastasis, and Resistance to Therapy
Barry J. Thompson
BIOESSAYS (2020)
Radiotherapy toxicity
Dirk De Ruysscher et al.
NATURE REVIEWS DISEASE PRIMERS (2019)
Cellular senescence in ionizing radiation (Review)
Zhengting Chen et al.
ONCOLOGY REPORTS (2019)
Regulation of TEAD Transcription Factors in Cancer Biology
Hyunbin D. Huh et al.
CELLS (2019)
HIF-1-Dependent Reprogramming of Glucose Metabolic Pathway of Cancer Cells and Its Therapeutic Significance
Ayako Nagao et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
YAP/TAZ Signaling and Resistance to Cancer Therapy
Chan D. K. Nguyen et al.
TRENDS IN CANCER (2019)
Role of HIF1 α Regulatory Factors in Stem Cells
Hyun Jik Lee et al.
INTERNATIONAL JOURNAL OF STEM CELLS (2019)
Ionizing radiation-induced cellular senescence promotes tissue fibrosis after radiotherapy. A review
Hoang Quy Nguyen et al.
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2018)
Radioresistant breast cancer cells exhibit increased resistance to chemotherapy and enhanced invasive properties due to cancer stem cells
Young Shin Ko et al.
ONCOLOGY REPORTS (2018)
Role of YAP/TAZ transcriptional regulators in resistance to anti-cancer therapies
Min Hwan Kim et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2017)
ATM, ATR, and DNA-PK: The Trinity at the Heart of the DNA Damage Response
Andrew N. Blackford et al.
MOLECULAR CELL (2017)
UCHL1-HIF-1 axis-mediated antioxidant property of cancer cells as a therapeutic target for radiosensitization
Ryota Nakashima et al.
SCIENTIFIC REPORTS (2017)
Commentary on Participation of p53 Protein in the Cellular Response to DNA Damage
Michael B. Kastan
CANCER RESEARCH (2016)
The Role of NF-kappa B Inhibitors in Cell Response to Radiation
Sajjad Molavi Pordanjani et al.
CURRENT MEDICINAL CHEMISTRY (2016)
Radiation-induced autophagy: mechanisms and consequences
Madhuri Chaurasia et al.
FREE RADICAL RESEARCH (2016)
RAC1 GTPase promotes the survival of breast cancer cells in response to hyper-fractionated radiation treatment
A. L. Hein et al.
ONCOGENE (2016)
The role of oxidative DNA damage in radiation induced bystander effect
Sophia Havaki et al.
CANCER LETTERS (2015)
Molecular Pathways: Hippo Signaling, a Critical Tumor Suppressor
Ana Sebio et al.
CLINICAL CANCER RESEARCH (2015)
The Accomplices of NF-κB Lead to Radioresistance
Miaomiao Bai et al.
CURRENT PROTEIN & PEPTIDE SCIENCE (2015)
The Role of Hypoxia-Induced miR-210 in Cancer Progression
Kyvan Dang et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2015)
Rac1 GTPase-deficient HeLa cells present reduced DNA repair, proliferation, and survival under UV or gamma irradiation
Gisele Espinha et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2015)
Radiation resistance: Cancer stem cells (CSCs) and their enigmatic pro-survival signaling
Ira Skvortsova et al.
SEMINARS IN CANCER BIOLOGY (2015)
A novel function of HER2/Neu in the activation of G2/M checkpoint in response to γ-irradiation
Y. Yan et al.
ONCOGENE (2015)
Ras inhibition enhances autophagy, which partially protects cells from death
Eran Schmukler et al.
Oncotarget (2015)
Ionizing Radiation-Induced DNA Damage, Response, and Repair
Wil L. Santivasi et al.
ANTIOXIDANTS & REDOX SIGNALING (2014)
Targeting PI3K/AKT/mTOR pathway in non small cell lung cancer
Claudia Fumarola et al.
BIOCHEMICAL PHARMACOLOGY (2014)
Unbiased analysis of pancreatic cancer radiation resistance reveals cholesterol biosynthesis as a novel target for radiosensitisation
J. J. Souchek et al.
BRITISH JOURNAL OF CANCER (2014)
ERBB Receptors: From Oncogene Discovery to Basic Science to Mechanism-Based Cancer Therapeutics
Carlos L. Arteaga et al.
CANCER CELL (2014)
Targeting DNA damage response in cancer therapy
Noriko Hosoya et al.
CANCER SCIENCE (2014)
Repair of ionizing radiation-induced DNA damage and risk of second cancer in childhood cancer survivors
Nadia Haddy et al.
CARCINOGENESIS (2014)
Sustained activation of DNA damage response in irradiated apoptosis-resistant cells induces reversible senescence associated with mTOR downregulation and expression of stem cell markers
Zhanna V. Chitikova et al.
CELL CYCLE (2014)
Functional interplay between ATM/ATR-mediated DNA damage response and DNA repair pathways in oxidative stress
Shan Yan et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2014)
Targeting the NFκB Signaling Pathways for Breast Cancer Prevention and Therapy
Wei Wang et al.
CURRENT MEDICINAL CHEMISTRY (2014)
Concomitant chemotherapy and radiation for the treatment of advanced-stage endometrial cancer
I. Wilkinson-Ryan et al.
GYNECOLOGIC ONCOLOGY (2014)
Radiation-induced signaling pathways that promote cancer cell survival (Review)
Ashley L. Hein et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2014)
Inhibition of autophagy enhances apoptosis induced by proteasome inhibitor bortezomib in human glioblastoma U87 and U251 cells
Xudong Zhang et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2014)
Molecular targets for cancer therapy in the PI3K/AKT/mTOR pathway
Jiri Polivka et al.
PHARMACOLOGY & THERAPEUTICS (2014)
The influence of AKT isoforms on radiation sensitivity and DNA repair in colon cancer cell lines
Sara Haggblad Sahlberg et al.
TUMOR BIOLOGY (2014)
Inhibition of RAC1 GTPase sensitizes pancreatic cancer cells to γ-irradiation
Ying Yan et al.
ONCOTARGET (2014)
被撤回的出版物: JNK confers 5-fluorouracil resistance in p53-deficient and mutant p53-expressing colon cancer cells by inducing survival autophagy (Retracted article. See vol. 11, 2021)
Xinbing Sui et al.
SCIENTIFIC REPORTS (2014)
Inhibition of ERK activation enhances the repair of double-stranded breaks via non-homologous end joining by increasing DNA-PKcs activation
Fengxiang Wei et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2013)
DNA repair mechanisms in dividing and non-dividing cells
Teruaki Iyama et al.
DNA REPAIR (2013)
Radiation-induced mitotic cell death and glioblastoma radioresistance: A new regulating pathway controlled by integrin-linked kinase, hypoxia-inducible factor 1alpha and survivin in U87 cells
Olivia Lanvin et al.
EUROPEAN JOURNAL OF CANCER (2013)
Molecular targets and mechanisms of radiosensitization using DNA damage response pathways
David R. Raleigh et al.
FUTURE ONCOLOGY (2013)
The Hippo pathway: regulators and regulations
Fa-Xing Yu et al.
GENES & DEVELOPMENT (2013)
Radiosensitivity enhancement of human hepatocellular carcinoma cell line SMMC-7721 by sorafenib through the MEK/ERK signal pathway
Xiao-Fang Dai et al.
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY (2013)
Targeting DNA double-strand break signalling and repair: recent advances in cancer therapy
Daniela Huehn et al.
SWISS MEDICAL WEEKLY (2013)
Endoplasmic reticulum stress sensitizes human esophageal cancer cell to radiation
Xue-Li Pang et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2013)
New insights into the roles of ATM and DNA-PKcs in the cellular response to oxidative stress
Benjamin P. C. Chen et al.
CANCER LETTERS (2012)
Rac signaling in breast cancer: A tale of GEFs and GAPs
Eva Wertheimer et al.
CELLULAR SIGNALLING (2012)
Typical cell signaling response to ionizing radiation: DNA damage and extranuclear damage
Hui Yu
CHINESE JOURNAL OF CANCER RESEARCH (2012)
Targeting the S and G2 checkpoint to treat cancer
Tao Chen et al.
DRUG DISCOVERY TODAY (2012)
Akt Promotes Post-Irradiation Survival of Human Tumor Cells through Initiation, Progression, and Termination of DNA-PKcs-Dependent DNA Double-Strand Break Repair
Mahmoud Toulany et al.
MOLECULAR CANCER RESEARCH (2012)
Regulation and Function of Autophagy during Cell Survival and Cell Death
Gautam Das et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2012)
RAC1 GTPase plays an important role in γ-irradiation induced G2/M checkpoint activation
Ying Yan et al.
BREAST CANCER RESEARCH (2012)
Involvement of Akt and mTOR in chemotherapeutic and hormonal-based drug resistance and response to radiation in breast cancer cells
Linda S. Steelman et al.
CELL CYCLE (2011)
K-RAS(V12) INDUCES AUTOCRINE PRODUCTION OF EGFR LIGANDS AND MEDIATES RADIORESISTANCE THROUGH EGFR-DEPENDENT AKT SIGNALING AND ACTIVATION OF DNA-PKCS
Minjmaa Minjgee et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2011)
TARGETING THE AKT/GSK3β/CYCLIN D1/CDK4 SURVIVAL SIGNALING PATHWAY FOR ERADICATION OF TUMOR RADIORESISTANCE ACQUIRED BY FRACTIONATED RADIOTHERAPY
Tsutomu Shimura et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2011)
DNA double-strand break - induced pro-survival signaling
Amy J. Hawkins et al.
RADIOTHERAPY AND ONCOLOGY (2011)
Pro-survival AKT and ERK signaling from EGFR and mutant EGFRvIII enhances DNA double-strand break repair in human glioma cells
Sarah E. Golding et al.
CANCER BIOLOGY & THERAPY (2009)
Up-regulation of autophagy in small intestine Paneth cells in response to total-body γ-irradiation
Nikolai V. Gorbunov et al.
JOURNAL OF PATHOLOGY (2009)
Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): An update on 93 randomised trials and 17,346 patients
Jean-Pierre Pignon et al.
RADIOTHERAPY AND ONCOLOGY (2009)
Targeting phosphoinositide 3-kinase - Moving towards therapy
Romina Marone et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2008)
γ-irradiation-induced DNA damage checkpoint activation involves feedback regulation between extracellular signal-regulated kinase 1/2 and BRCA1
Ying Yan et al.
CANCER RESEARCH (2008)
Activation of epidermal growth factor receptor and its downstream signaling pathway by nitric oxide in response to ionizing radiation
Hyung-Chahn Lee et al.
MOLECULAR CANCER RESEARCH (2008)
Targeting of AKT1 enhances radiation toxicity of human tumor cells by inhibiting DNA-PKcs-dependent DNA double-strand break repair
Mahmoud Toulany et al.
MOLECULAR CANCER THERAPEUTICS (2008)
Mammalian Rho GTPases:: new insights into their functions from in vivo studies
Sarah J. Heasman et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
PARP-1 activation in the ERK signaling pathway
Malka Cohen-Armon
TRENDS IN PHARMACOLOGICAL SCIENCES (2007)
Akt phosphorylates Mstl and prevents its proteolytic activation, blocking FOXO3 phosphorylation and nuclear translocation
Sung-Wuk Jang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Elucidation of a universal size-control mechanism in Drosophila and mammals
Jixin Dong et al.
CELL (2007)
Stimulated PI3K-AKT signaling mediated through ligand or radiation - Induced EGFR depends indirectly, but not directly, on constitutive K-Ras activity
Mahmoud Toulany et al.
MOLECULAR CANCER RESEARCH (2007)
Contrasting roles of neuronal Msk1 and Rsk2 in Bad phosphorylation and feedback regulation of Erk signalling
C. J. Clark et al.
JOURNAL OF NEUROCHEMISTRY (2007)
Irradiation-induced G2/M checkpoint response requires ERK1/2 activation
Y. Yan et al.
ONCOGENE (2007)
ERK1/2-dependent phosphorylation of BimEL promotes its rapid dissociation from Mcl-1 and Bcl-xL
Katherine E. Ewings et al.
EMBO JOURNAL (2007)
Temporal onset of hypoxia and oxidative stress after pulmonary irradiation
Katharina Fleckenstein et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2007)
Extracellular signal-related kinase positively regulates ataxia telangiectasia mutated, homologous recombination repair, and the DNA damage response
Sarah E. Golding et al.
CANCER RESEARCH (2007)
DNA-independent PARP-1 activation by phosphorylated ERK2 increases EIk1 activity: A link to histone acetylation
Malka Cohen-Armon et al.
MOLECULAR CELL (2007)
Radiation-induced cell signaling: inside-out and outside-in
Kristoffer Valerie et al.
MOLECULAR CANCER THERAPEUTICS (2007)
FKHRL1-mediated expression of Noxa and Bim induces apoptosis via the mitochondria in neuroblastoma cells
P. Obexer et al.
CELL DEATH AND DIFFERENTIATION (2007)
ErbB receptors: new insights on mechanisms and biology
Bryan Linggi et al.
TRENDS IN CELL BIOLOGY (2006)
Ras, PI(3)K and mTOR signalling controls tumour cell growth
Reuben J. Shaw et al.
NATURE (2006)
The Rac and Rho hall of fame - A decade of hypertrophic signaling hits
JH Brown et al.
CIRCULATION RESEARCH (2006)
Rac1 modulates sphingosine 1-phosphate-mediated activation of phosphoinositide 3-kinase/Akt signaling pathways in vascular endothelial cells
E Gonzalez et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Evidence that Ser87 of BimEL is phosphorylated by Akt and regulates BimEL apoptotic function
XJ Qi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks
A Jazayeri et al.
NATURE CELL BIOLOGY (2006)
Radiation-induced epidermal growth factor receptor nuclear import is linked to activation of DNA-dependent protein kinase
K Dittmann et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Selective inhibition of Ras, phosphoinositide 3 kinase, and Akt isoforms increases the radiosensitivity of human carcinoma cell lines
IA Kim et al.
CANCER RESEARCH (2005)
Inhibition of radiation-induced EGFR nuclear import by C225 (Cetuximab) suppresses DNA-PK activity
K Dittmann et al.
RADIOTHERAPY AND ONCOLOGY (2005)
P53C-terminal phosphorylation by CHM and CHK2 participates in the regulation of DNA-Damage-induced C-terminal acetylation
YH Ou et al.
MOLECULAR BIOLOGY OF THE CELL (2005)
Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage
J Falck et al.
NATURE (2005)
Significance of histological response to preoperative chemoradiotherapy for pancreatic cancer
RR White et al.
ANNALS OF SURGICAL ONCOLOGY (2005)
G2 damage checkpoints: what is the turn-on?
MJ O'Connell et al.
JOURNAL OF CELL SCIENCE (2005)
Akt phosphorylation and stabilization of X-linked inhibitor of apoptosis protein (XIAP)
HC Dan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints
A Sancar et al.
ANNUAL REVIEW OF BIOCHEMISTRY (2004)
Phosphorylation of Bax Ser184 by Akt regulates its activity and apoptosis in neutrophils
SJ Gardai et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Biological chemistry of reactive oxygen and nitrogen and radiation-induced signal transduction mechanisms
RB Mikkelsen et al.
ONCOGENE (2003)
MAPK pathways in radiation responses
P Dent et al.
ONCOGENE (2003)
Lovastatin causes sensitization of HeLa cells to ionizing radiation-induced apoptosis by the abrogation of G2 blockage
G Fritz et al.
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY (2003)
PAKI phosphorylation of MEK1 regulates fibronectin-stimulated MAPK activation
JK Slack-Davis et al.
JOURNAL OF CELL BIOLOGY (2003)
Inhibition of caspase-9 through phosphorylation at Thr 125 by ERK MAPK
LA Allan et al.
NATURE CELL BIOLOGY (2003)
Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes
L Zou et al.
SCIENCE (2003)
Dual phosphorylation controls Cdc25 phosphatases and mitotic entry
DV Bulavin et al.
NATURE CELL BIOLOGY (2003)
Inactivation of the forkhead transcription factor FoxO3 is essential for PKB-mediated survival of hematopoietic progenitor cells by kit ligand
M Engström et al.
EXPERIMENTAL HEMATOLOGY (2003)
PKCε-mediated ERK1/2 activation involved in radiation-induced cell death in NIH3T3 cells
YJ Lee et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2003)
Enhanced glycogen synthase kinase-3β activity mediates hypoxia-induced apoptosis of vascular smooth muscle cells and is prevented by glucose transport and metabolism
RD Loberg et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
MEK/ERK pathway protects ionizing radiation-induced loss of mitochondrial membrane potential and cell death in lymphocytic leukemia cells
T Shonai et al.
CELL DEATH AND DIFFERENTIATION (2002)
Rac-PAK signaling stimulates extracellular signal- regulated kinase (ERK) activation by regulating formation of MEKI-ERK complexes
ST Eblen et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Ionizing radiation activates Erb-B receptor dependent Akt and p70 S6 kinase signaling in carcinoma cells
JN Contessa et al.
ONCOGENE (2002)
ERK activation mediates cell cycle arrest and apoptosis after DNA damage independently of p53
DM Tang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Rac1 and RhoG promote cell survival by the activation of PI3K and Akt, independently of their ability to stimulate JNK and NF-κB
C Murga et al.
ONCOGENE (2002)
The protein kinase PKB/Akt regulates cell survival and apoptosis by inhibiting Bax conformational change
H Yamaguchi et al.
ONCOGENE (2001)
Caspase-3 activation induced by inhibition of mitochondrial complex I is facilitated by glycogen synthase kinase-3β and attenuated by lithium
TD King et al.
BRAIN RESEARCH (2001)
Checking out the G2/M transition
VAJ Smits et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION (2001)
Epidermal growth factor receptor-dependent control of keratinocyte survival and Bcl-xL expression through a MEK-dependent pathway
M Jost et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Matrix attachment regulates Fas-induced apoptosis in endothelial cells: A role for c-Flip and implications for anoikis
F Aoudjit et al.
JOURNAL OF CELL BIOLOGY (2001)