4.6 Article

Deep Learning-Based Brain Computed Tomography Image Classification with Hyperparameter Optimization through Transfer Learning for Stroke

Journal

DIAGNOSTICS
Volume 12, Issue 4, Pages -

Publisher

MDPI
DOI: 10.3390/diagnostics12040807

Keywords

machine learning; neuroradiology; computed tomography; stroke; classification

Funding

  1. Chang Gung Medical Research Program [CMRPG2J0141, CMRPG2J0142]

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This study proposed the use of deep learning models based on convolutional neural networks (CNNs) for efficient classification of different types of strokes based on unenhanced brain CT images. After testing and comparison, it was found that CNN-2 and ResNet-50 performed better than VGG-16 and previous studies. Therefore, these models can be applied in clinical scenarios after appropriate optimization.
Brain computed tomography (CT) is commonly used for evaluating the cerebral condition, but immediately and accurately interpreting emergent brain CT images is tedious, even for skilled neuroradiologists. Deep learning networks are commonly employed for medical image analysis because they enable efficient computer-aided diagnosis. This study proposed the use of convolutional neural network (CNN)-based deep learning models for efficient classification of strokes based on unenhanced brain CT image findings into normal, hemorrhage, infarction, and other categories. The included CNN models were CNN-2, VGG-16, and ResNet-50, all of which were pretrained through transfer learning with various data sizes, mini-batch sizes, and optimizers. Their performance in classifying unenhanced brain CT images was tested thereafter. This performance was then compared with the outcomes in other studies on deep learning-based hemorrhagic or ischemic stroke diagnoses. The results revealed that among our CNN-2, VGG-16, and ResNet-50 analyzed by considering several hyperparameters and environments, the CNN-2 and ResNet-50 outperformed the VGG-16, with an accuracy of 0.9872; however, ResNet-50 required a longer time to present the outcome than did the other networks. Moreover, our models performed much better than those reported previously. In conclusion, after appropriate hyperparameter optimization, our deep learning-based models can be applied to clinical scenarios where neurologist or radiologist may need to verify whether their patients have a hemorrhage stroke, an infarction, and any other symptom.

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