Impact of COVID-19 In-hospital Mortality in Chagas Disease Patients

Article Parasitology

Chagas disease mortality during the coronavirus disease 2019 pandemic: A Brazilian referral center experience

Alejandro Marcel Hasslocher-Moreno et al.

Summary: During the COVID-19 pandemic, mortality rates were higher in patients with Chagas disease, and comorbidities were associated with a poorer prognosis in Chagas disease and COVID-19.

REVISTA DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL (2022)

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Article Infectious Diseases

COVID-19 as the leading cause of hospital deaths in the Brazilian public health system in 2020

Ivan Ricardo Zimmermann et al.

Summary: According to the study, the number of hospital deaths in Brazil increased by 16.7% in 2020 compared to 2019, with COVID-19 accounting for 19.5% of all hospital deaths, surpassing other diseases. During the pandemic, COVID-19 became the leading cause of death in Brazilian hospitals.

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2021)

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Article Multidisciplinary Sciences

Chagas disease and SARS-CoV-2 coinfection does not lead to worse in-hospital outcomes

Israel Molina et al.

Summary: Chagas disease remains a major public health burden in Latin America. This study assessed the clinical characteristics and in-hospital outcomes of patients with Chagas disease and COVID-19, finding higher rates of heart failure and atrial fibrillation in Chagas patients but similar in-hospital outcomes between the Chagas and non-Chagas patients. Further investigation is needed to understand the lower C-reactive protein levels in Chagas patients.

SCIENTIFIC REPORTS (2021)

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Article Multidisciplinary Sciences

Prevalence of metabolic syndrome and associated factors among patients with chronic Chagas disease

Isis Gabrielli Gomes Xavier et al.

Summary: The study identified a high prevalence of MetS in Brazilian chronic Chagas disease patients, with age, education levels, and cardiac form with heart failure being independently associated factors.

PLOS ONE (2021)

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Review Cardiac & Cardiovascular Systems

Chagas heart disease: An overview of diagnosis, manifestations, treatment, and care

Roberto M. Saraiva et al.

Summary: Chagas heart disease, caused by Trypanosoma cruzi, affects around 30% of patients. It is classified into four stages based on criteria including ECG, echocardiogram, and clinical findings. CHD presents with various clinical manifestations, with sudden cardiac death, heart failure, and stroke being the main complications. Sudden cardiac death is the most common cause of death in CHD patients, followed by heart failure and stroke.

WORLD JOURNAL OF CARDIOLOGY (2021)

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Review Biology

Risk of COVID-19 in Chagas Disease Patients: What Happen with Cardiac Affectations?

Alejandro Diaz-Hernandez et al.

Summary: This review explores the relationship between Chagas disease and co-infection with the SARS-Cov-2 virus, highlighting the lack of information on the consequences for patients. It emphasizes the importance of access to medical care for co-infected individuals and the need for further research to understand the implications of co-infections in Chagas disease patients.

BIOLOGY-BASEL (2021)

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Article Parasitology

Temporal changes in the clinical-epidemiological profile of patients with Chagas disease at a referral center in Brazil

Alejandro Marcel Hasslocher-Moreno et al.

Summary: The study found that patients with CD were mainly white, with low levels of education, and presented with an indeterminate form of the disease. Over time, the age of patients seeking treatment gradually increased, reflecting an aging patient population. Additionally, there was a progressive decrease in the number of new patients.

REVISTA DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL (2021)

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Review Radiology, Nuclear Medicine & Medical Imaging

Effectiveness of COVID-19 diagnosis and management tools: A review

W. Alsharif et al.

Summary: RT-PCR has low sensitivity in diagnosing COVID-19 compared to CT, which shows typical imaging features helpful in rectifying false negative results from RT-PCR. While CT is a powerful tool in COVID-19 diagnosis, its low specificity and challenges in differentiation from other viral pneumonia on CT scans make it insufficient alone. AI may aid radiologists in distinguishing COVID-19 from other pneumonia diseases.

RADIOGRAPHY (2021)

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Article Radiology, Nuclear Medicine & Medical Imaging