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National Lipid Association Recommendations for Patient-Centered Management of Dyslipidemia: Part 1-Full Report
Terry A. Jacobson et al.
JOURNAL OF CLINICAL LIPIDOLOGY (2015)
ANGPTL3 blockade with a human monoclonal antibody reduces plasma lipids in dyslipidemic mice and monkeys
Viktoria Gusarova et al.
JOURNAL OF LIPID RESEARCH (2015)
Safety and efficacy of fibrate-statin combination therapy compared to fibrate monotherapy in patients with dyslipidemia: A meta-analysis
Hye Duck Choi et al.
VASCULAR PHARMACOLOGY (2015)
Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction
Ron Do et al.
NATURE (2015)
Fibrates for secondary prevention of cardiovascular disease and stroke
D. Wang et al.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2015)
A Novel Apolipoprotein C-II Mimetic Peptide That Activates Lipoprotein Lipase and Decreases Serum Triglycerides in Apolipoprotein E-Knockout Mice
Marcelo J. A. Amar et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2015)
Identification of a small molecule that stabilizes lipoprotein lipase in vitro and lowers triglycerides in vivo
Mikael Larsson et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2014)
Low Nonfasting Triglycerides and Reduced All-Cause Mortality: A Mendelian Randomization Study
Mette Thomsen et al.
CLINICAL CHEMISTRY (2014)
Risk prediction with triglycerides in patients with stable coronary disease on statin treatment
Christian Werner et al.
CLINICAL RESEARCH IN CARDIOLOGY (2014)
Postprandial lipemia as a cardiometabolic risk factor
Angela Pirillo et al.
CURRENT MEDICAL RESEARCH AND OPINION (2014)
Genetics and Causality of Triglyceride-Rich Lipoproteins in Atherosclerotic Cardiovascular Disease
Robert S. Rosenson et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2014)
Loss-of-Function Mutations in APOC3 and Risk of Ischemic Vascular Disease
Anders Berg Jorgensen et al.
NEW ENGLAND JOURNAL OF MEDICINE (2014)
Loss-of-Function Mutations in APOC3, Triglycerides, and Coronary Disease
Jacy Crosby et al.
NEW ENGLAND JOURNAL OF MEDICINE (2014)
Combined Effects of Oligofructose and Bifidobacterium animalis on Gut Microbiota and Glycemia in Obese Rats
Marc R. Bomhof et al.
OBESITY (2014)
Shear stress modulates VCAM-1 expression in response to TNF-α and dietary lipids via interferon regulatory factor-1 in cultured endothelium
J. Sherrod DeVerse et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2013)
Induction of ATF3 Gene Network by Triglyceride-Rich Lipoprotein Lipolysis Products Increases Vascular Apoptosis and Inflammation
Hnin H. Aung et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2013)
Elevated Remnant Cholesterol Causes Both Low-Grade Inflammation and Ischemic Heart Disease, Whereas Elevated Low-Density Lipoprotein Cholesterol Causes Ischemic Heart Disease Without Inflammation
Anette Varbo et al.
CIRCULATION (2013)
The Role of Fibrate Treatment in Dyslipidemia: An Overview
Niki Katsiki et al.
CURRENT PHARMACEUTICAL DESIGN (2013)
Genetically elevated non-fasting triglycerides and calculated remnant cholesterol as causal risk factors for myocardial infarction
Anders Berg Jorgensen et al.
EUROPEAN HEART JOURNAL (2013)
HPS2-THRIVE randomized placebo-controlled trial in 25 673 high-risk patients of ER niacin/laropiprant: trial design, pre-specified muscle and liver outcomes, and reasons for stopping study treatment
Richard Haynes et al.
EUROPEAN HEART JOURNAL (2013)
Efficacy and long-term safety of alipogene tiparvovec (AAV1-LPLS447X) gene therapy for lipoprotein lipase deficiency: an open-label trial
D. Gaudet et al.
GENE THERAPY (2013)
Biochemistry and pathophysiology of intravascular and intracellular lipolysis
Stephen G. Young et al.
GENES & DEVELOPMENT (2013)
Beneficial Metabolic Effects of a Probiotic via Butyrate-induced GLP-1 Hormone Secretion
Hariom Yadav et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Using Mendelian randomization to determine causative factors in cardiovascular disease
C. T. Johansen et al.
JOURNAL OF INTERNAL MEDICINE (2013)
Structural and functional analysis of APOA5 mutations identified in patients with severe hypertriglyceridemia
Elena Mendoza-Barbera et al.
JOURNAL OF LIPID RESEARCH (2013)
Richness of human gut microbiome correlates with metabolic markers
Emmanuelle Le Chatelier et al.
NATURE (2013)
Dietary intervention impact on gut microbial gene richness
Aurelie Cotillard et al.
NATURE (2013)
Common variants associated with plasma triglycerides and risk for coronary artery disease
Ron Do et al.
NATURE GENETICS (2013)
Triglyceride-Rich Lipoprotein Modulates Endothelial Vascular Cell Adhesion Molecule (VCAM)-1 Expression via Differential Regulation of Endoplasmic Reticulum Stress
Ying I. Wang et al.
PLOS ONE (2013)
Efficacy and Safety of Eicosapentaenoic Acid Ethyl Ester (AMR101) Therapy in Statin-Treated Patients With Persistent High Triglycerides (from the ANCHOR Study)
Christie M. Ballantyne et al.
AMERICAN JOURNAL OF CARDIOLOGY (2012)
Apolipoprotein A-IV regulates chylomicron metabolism-mechanism and function
Alison B. Kohan et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2012)
Postprandial accumulation of chylomicrons and chylomicron remnants is determined by the clearance capacity
Martin Adiels et al.
ATHEROSCLEROSIS (2012)
IRF-1 and miRNA126 Modulate VCAM-1 Expression in Response to a High-Fat Meal
Chongxiu Sun et al.
CIRCULATION RESEARCH (2012)
Omega 3 Fatty Acids and Cardiovascular Outcomes Systematic Review and Meta-Analysis
Sradha Kotwal et al.
CIRCULATION-CARDIOVASCULAR QUALITY AND OUTCOMES (2012)
Residual Cardiovascular Risk Despite Optimal LDL Cholesterol Reduction with Statins: The Evidence, Etiology, and Therapeutic Challenges
Uchechukwu K. Sampson et al.
CURRENT ATHEROSCLEROSIS REPORTS (2012)
Effects of eicosapentaenoic acid and docosahexaenoic acid on low-density lipoprotein cholesterol and other Lipids: A review
Terry A. Jacobson et al.
JOURNAL OF CLINICAL LIPIDOLOGY (2012)
Triglyceride-Rich Lipoprotein Regulates APOB48 Receptor Gene Expression in Human THP-1 Monocytes and Macrophages
Beatriz Bermudez et al.
JOURNAL OF NUTRITION (2012)
Biophysical and biochemical mechanisms by which dietary N-3 polyunsaturated fatty acids from fish oil disrupt membrane lipid rafts
Saame Raza Shaikh
JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2012)
Niacin and Statin Combination Therapy for Atherosclerosis Regression and Prevention of Cardiovascular Disease Events Reconciling the AIM-HIGH (Atherothrombosis Intervention in Metabolic Syndrome With Low HDL/High Triglycerides: Impact on Global Health Outcomes) Trial With Previous Surrogate Endpoint Trials
Erin D. Michos et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2012)
Effect of Long-Term Exposure to Lower Low-Density Lipoprotein Cholesterol Beginning Early in Life on the Risk of Coronary Heart Disease A Mendelian Randomization Analysis
Brian A. Ference et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2012)
Endothelial inflammation correlates with subject triglycerides and waist size after a high-fat meal
Ying I. Wang et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2011)
Eicosapentaenoic acid administration attenuates the pro-inflammatory properties of VLDL by decreasing its susceptibility to lipoprotein lipase in macrophages
Yasutaka Jinno et al.
ATHEROSCLEROSIS (2011)
Apolipoprotein A-V; a potent triglyceride reducer
Stefan K. Nilsson et al.
ATHEROSCLEROSIS (2011)
Angiopoietin-like proteins: emerging targets for treatment of obesity and related metabolic diseases
Tsuyoshi Kadomatsu et al.
FEBS JOURNAL (2011)
Omega-3 Fatty Acids and Cardiovascular Disease Effects on Risk Factors, Molecular Pathways, and Clinical Events
Dariush Mozaffarian et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2011)
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease
Heribert Schunkert et al.
NATURE GENETICS (2011)
Niacin in Patients with Low HDL Cholesterol Levels Receiving Intensive Statin Therapy
William E. Boden et al.
NEW ENGLAND JOURNAL OF MEDICINE (2011)
Influence of chylomicron remnants on human monocyte activation in vitro
C. Bentley et al.
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES (2011)
Intravenous Injection of Apolipoprotein A-V Reconstituted High-Density Lipoprotein Decreases Hypertriglyceridemia in apoav-/- Mice and Requires Glycosylphosphatidylinositol-Anchored High-Density Lipoprotein-Binding Protein 1
Xiao Shu et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2010)
GPIHBP1 Is Responsible for the Entry of Lipoprotein Lipase into Capillaries
Brandon S. J. Davies et al.
CELL METABOLISM (2010)
Effects of fibrates on cardiovascular outcomes: a systematic review and meta-analysis
Min Jun et al.
LANCET (2010)
Biological, clinical and population relevance of 95 loci for blood lipids
Tanya M. Teslovich et al.
NATURE (2010)
Exome Sequencing, ANGPTL3 Mutations, and Familial Combined Hypolipidemia
Kiran Musunuru et al.
NEW ENGLAND JOURNAL OF MEDICINE (2010)
Niacin and fibrates in atherogenic dyslipidemia: Pharmacotherapy to reduce cardiovascular risk
M. John Chapman et al.
PHARMACOLOGY & THERAPEUTICS (2010)
Lipoprotein lipase: from gene to obesity
Hong Wang et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2009)
Atorvastatin and fenofibrate increase apolipoprotein AV and decrease triglycerides by up-regulating peroxisome proliferator-activated receptor-α
Xian-sheng Huang et al.
BRITISH JOURNAL OF PHARMACOLOGY (2009)
Chronic Endoplasmic Reticulum Stress Activates Unfolded Protein Response in Arterial Endothelium in Regions of Susceptibility to Atherosclerosis
Mete Civelek et al.
CIRCULATION RESEARCH (2009)
Diabetic dyslipidemia: beyond LDL
M. Merkel
DEUTSCHE MEDIZINISCHE WOCHENSCHRIFT (2009)
Triglyceride-rich lipoprotein lipolysis releases neutral and oxidized FFAs that induce endothelial cell inflammation
Limin Wang et al.
JOURNAL OF LIPID RESEARCH (2009)
Triglyceride-rich lipoprotein lipolysis increases aggregation of endothelial cell membrane microdomains and produces reactive oxygen species
Limin Wang et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2008)
Omega-3 fatty acids and coronary heart disease risk: Clinical and mechanistic perspectives
William S. Harris et al.
ATHEROSCLEROSIS (2008)
Effects of EPA on coronary artery disease in hypercholesterolemic patients with multiple risk factors: Sub-analysis of primary prevention cases from the Japan EPA Lipid Intervention Study (JELIS)
Yasushi Saito et al.
ATHEROSCLEROSIS (2008)
Atheroprotective Effect of Human Apolipoprotein A5 in a Mouse Model of Mixed Dyslipidemia
Roxane M. Mansouri et al.
CIRCULATION RESEARCH (2008)
Detection of apolipoproteins B-48 and B-100 carrying particles in lipoprotein fractions extracted from human aortic atherosclerotic plaques in sudden cardiac death cases
Takamitsu Nakano et al.
CLINICA CHIMICA ACTA (2008)
Variation in ANGPTL4 and risk of coronary heart disease: the Atherosclerosis Risk in Communities Study
Aaron R. Folsom et al.
METABOLISM-CLINICAL AND EXPERIMENTAL (2008)
A Null Mutation in Human APOC3 Confers a Favorable Plasma Lipid Profile and Apparent Cardioprotection
Toni I. Pollin et al.
SCIENCE (2008)
Development and Physiological Regulation of Intestinal Lipid Absorption. I. Development of intestinal lipid absorption: cellular events in chylomicron assembly and secretion
Dennis D. Black
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2007)
Fasting compared with nonfasting triglycerides and risk of cardiovascular events in women
Sandeep Bansal et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2007)
Nonfasting triglycerides and risk of myocardial infarction, ischemic heart disease, and death in men and women
Borge G. Nordestgaard et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2007)
Lipid-lowering effects of anti-angiopoietin-like 4 antibody recapitulate the lipid phenotype found in angiopoietin-like 4 knockout mice
Urvi Desai et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Mechanisms involved in chylomicron remnant lipid uptake by macrophages
E. Bravo et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2007)
The induction of macrophage foam cell formation by chylomicron remnants
K. M. Botham et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2007)
Glycosylphosphatidylinositol-anchored high-density lipoprotein-binding protein 1 plays a critical role in the lipolytic processing of chylomicrons
Anne P. Beigneux et al.
CELL METABOLISM (2007)
The role of lipolysis in mediating the proinflammatory effects of very low density lipoproteins in mouse peritoneal macrophages
Viswanathan Saraswathi et al.
JOURNAL OF LIPID RESEARCH (2006)
Sequence variations in PCSK9, low LDL, and protection against coronary heart disease
JC Cohen et al.
NEW ENGLAND JOURNAL OF MEDICINE (2006)
Chylomicron remnants stimulate release of interleukin-1β by THP-1 cells
Takahiro Okumura et al.
JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS (2006)
Lipoprotein lipase S447X - A naturally occurring gain-of-function mutation
Jaap Rip et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2006)
Angpt/3-null mice show low plasma lipid concentrations by enhanced lipoprotein lipase activity
K Fujimoto et al.
EXPERIMENTAL ANIMALS (2006)
Remnant lipoproteinemia is a risk factor for endothelial vasomotor dysfunction and coronary artery disease in metabolic syndrome
T Nakamura et al.
ATHEROSCLEROSIS (2005)
Mitochondrial glycerol-3-phosphate acyltransferase-1 is essential in liver for the metabolism of excess acyl-CoAs
LE Hammond et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Prevention of hepatic steatosis and hepatic insulin resistance in mitochondrial acyl-CoA:glycerol-sn-3-phosphate acyltransferase 1 knockout mice
S Neschen et al.
CELL METABOLISM (2005)
Oligofructose promotes satiety in rats fed a high-fat diet: Involvement of glucagon-like peptide-1
PD Cani et al.
OBESITY RESEARCH (2005)
Very low density lipoprotein potentiates tumor necrosis factor-α expression in macrophages
MM Stollenwerk et al.
ATHEROSCLEROSIS (2005)
Cilostazol prevents remnant lipoprotein particle-induced monocyte adhesion to endothelial cells by suppression of adhesion molecules and monocyte chemoattractant protein-1 expression via lectin-like receptor for oxidized low-density lipoprotein receptor activation
SY Park et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2005)
Pitavastatin inhibits remnant lipoprotein-induced macrophage foam cell formation through apoB48 receptor-dependent mechanism
A Kawakami et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2005)
Remnant lipoprotein particles induce apoptosis in endothelial cells by NAD(P)H oxidase-mediated production of superoxide and cytokines via lectin-like oxidized low-density lipoprotein receptor-1 activation - Prevention by cilostazol
HK Shin et al.
CIRCULATION (2004)
Phenotypes, genotypes and response to statin therapy
MJ Caslake et al.
CURRENT OPINION IN LIPIDOLOGY (2004)
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
U Özcan et al.
SCIENCE (2004)
Induction of postprandial inflammatory response in adult onset growth hormone deficiency is related to plasma remnant-like particle-cholesterol concentration
TB Twickler et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2003)
Increased serum triglyceride clearance and elevated high-density lipoprotein 2 and 3 cholesterol during treatment of primary hypertriglyceridemia with bezafibrate
N Sakuma et al.
CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL (2003)
Angptl3 regulates lipid metabolism in mice
R Koishi et al.
NATURE GENETICS (2002)
Postprandial elevation of remnant lipoprotein leads to endothelial dysfunction
J Funada et al.
CIRCULATION JOURNAL (2002)
The internal redox balance of the cells influences the metabolism of lipids of dietary origin by J774 macrophages: Implications for foam cell formation
M Napolitano et al.
JOURNAL OF VASCULAR RESEARCH (2001)
Hypertriglyceridemia and other factors associated with plasma viscosity
RS Rosenson et al.
AMERICAN JOURNAL OF MEDICINE (2001)
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