Highly Pathogenic Avian Influenza A(H5Nx) Virus of Clade 2.3.4.4b Emerging in Tibet, China, 2021

Article Biology

Genetic and biological characteristics of the globally circulating H5N8 avian influenza viruses and the protective efficacy offered by the poultry vaccine currently used in China

Pengfei Cui et al.

Summary: The study analyzed samples of wild birds and poultry in China, identifying two distinct genotypes of the H5N8 virus circulating in different bird species. The research also revealed the origin and spatiotemporal spread of these genotypes in 2020 and 2021. Additionally, the study showed that vaccinated poultry in China were fully protected against H5N8 virus challenge, highlighting the importance of vaccination to prevent the spread of H5N8 avian influenza.

SCIENCE CHINA-LIFE SCIENCES (2022)

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Article Immunology

Emergence, prevalence, and evolution of H5N8 avian influenza viruses in central China, 2020

Xiang Li et al.

Summary: The study reveals the transmission pathway of highly pathogenic H5N8 avian influenza viruses in central China, suggesting that swans play an important role in the spread and monitoring of the virus.

EMERGING MICROBES & INFECTIONS (2022)

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Article Veterinary Sciences

Rapid Emergence of the Reassortant 2.3.4.4b H5N2 Highly Pathogenic Avian Influenza Viruses in a Live Poultry Market in Xinjiang, Northwest China

Dilihuma Aji et al.

AVIAN DISEASES (2021)

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Article Immunology

Emergence and spread of novel H5N8, H5N5 and H5N1 clade 2.3.4.4 highly pathogenic avian influenza in 2020

Nicola S. Lewis et al.

Summary: Analyses of highly pathogenic H5 viruses from poultry outbreaks across a wide Eurasian region since July 2020, including the Russian Federation, Republics of Iraq and Kazakhstan, and recent detections in migratory waterfowl in the Netherlands, revealed a variety of H5Nx subtypes posing a threat to poultry production, food security and veterinary public health.

EMERGING MICROBES & INFECTIONS (2021)

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Article Virology

Emergence, Evolution, and Pathogenicity of Influenza A(H7N4) Virus in Shorebirds in China

Hongliang Chai et al.

JOURNAL OF VIROLOGY (2021)

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Article Infectious Diseases

Isolation of clade 2.3.4.4b A(H5N8), a highly pathogenic avian influenza virus, from a worker during an outbreak on a poultry farm, Russia, December 2020

Olga G Pyankova et al.

Eurosurveillance (2021)

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Letter Immunology

Emerging highly pathogenic avian influenza (H5N8) virus in migratory birds in Central China, 2020

Jiasong Xiong et al.

Summary: The study identified eleven highly pathogenic avian influenza H5N8 viruses that were detected in migratory birds in Central China between November and December 2020. These strains were found to be highly homologous to those isolated in Europe from October to December 2020, suggesting a possible spread from Siberia via migratory birds. The research also revealed that H5N8 virus infection in migratory birds could lead to severe pathological damage and high viral load in multiple organs.

EMERGING MICROBES & INFECTIONS (2021)

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Letter Immunology

Highly Pathogenic Avian Influenza A(H5N8) Virus in Swans, China, 2020

Xiang Li et al.

Summary: In October 2020, highly pathogenic avian influenza A(H5N8) viruses were detected in 2 dead swans in Inner Mongolia, China. Genetic analysis showed that the H5N8 isolates belong to Glade 2.3.4.4b and cluster with the H5N8 viruses isolated in Eurasia in the fall of 2020.

EMERGING INFECTIOUS DISEASES (2021)

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Article Immunology