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C Napoli et al.
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Distinct cysteine residues in Keap1 are required for Keap1-dependent ubiquitination of Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stress
DD Zhang et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
The polymorphism of manganese superoxide dismutase is associated with diabetic nephropathy in Japanese type 2 diabetic patients
T Nomiyama et al.
JOURNAL OF HUMAN GENETICS (2003)
Increased oxidative stress and hypozincemia in male obesity
M Ozata et al.
CLINICAL BIOCHEMISTRY (2002)
Two domains of Nrf2 cooperatively bind CBP, a CREB binding protein, and synergistically activate transcription
Y Katoh et al.
GENES TO CELLS (2001)