4.7 Article

Agaricus Mushroom-Enriched Diets Modulate the Microbiota-Gut-Brain Axis and Reduce Brain Oxidative Stress in Mice

Related references

Note: Only part of the references are listed.
Review Biochemistry & Molecular Biology

Gut Microbiota and Short Chain Fatty Acids: Implications in Glucose Homeostasis

Piero Portincasa et al.

Summary: The gut microbiota consists of trillions of commensal microorganisms including bacteria, fungi, and viruses, which coexist in symbiosis with the host and have profound effects on human health. Short chain fatty acids (SCFAs) are the most abundant bacterial metabolites in the human body and play an important role in metabolic, endocrine, and immune functions. Diet can influence the composition and activity of the gut microbiota, as well as SCFAs production and metabolic effects.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

Review Nutrition & Dietetics

Polyphenol-Mediated Gut Microbiota Modulation: Toward Prebiotics and Further

Maria Carolina Rodriguez-Daza et al.

Summary: The genome of gut microbes encodes enzymes that metabolize unabsorbed (poly)phenols, impacting host health. While certain probiotics transform these compounds into bioactive metabolites, other gut symbionts benefit from (poly)phenols without metabolizing them. This dual microbial effect, termed "duplibiotic," promotes beneficial gut bacteria and may have therapeutic potential for metabolic disturbances and gut dysbiosis.

FRONTIERS IN NUTRITION (2021)

Review Biology

Association of Gut Microbiome Dysbiosis with Neurodegeneration: Can Gut Microbe-Modifying Diet Prevent or Alleviate the Symptoms of Neurodegenerative Diseases?

Li Yang Tan et al.

Summary: Recent studies have shown that gut dysbiosis may precede the onset of cognitive deficits, highlighting the importance of the balance between pathogenic microbes and probiotic populations for systemic inflammation and neuronal health. The gut microbiome can be influenced by lifestyle and dietary choices, offering opportunities for treatment through individual-specific control of human behavior. Early dietary interventions may be beneficial for the prevention and treatment of progressive neurodegenerative diseases.

LIFE-BASEL (2021)

Review Gastroenterology & Hepatology

The Microbiota-Gut-Brain Axis: From Motility to Mood

Kara G. Margolis et al.

Summary: The gut-brain axis is crucial in maintaining homeostasis, with the microbiome playing a significant role in modulating signaling along this axis. This axis impacts disorders like irritable bowel syndrome and mood disorders, with serotonin being a key neurotransmitter involved in these conditions. More research is needed before these findings can be applied for diagnostic and therapeutic purposes in patient populations.

GASTROENTEROLOGY (2021)

Article Biochemistry & Molecular Biology

Natural Food Supplements Reduce Oxidative Stress in Primary Neurons and in the Mouse Brain, Suggesting Applications in the Prevention of Neurodegenerative Diseases

Miriam Bobadilla et al.

Summary: The study showed that certain bioactive natural supplements may have important protective properties against oxidative stress in the brain, including reducing reactive oxygen species levels, decreasing caspase-3 activity, and increasing the activity of antioxidant enzymes with preventive treatment.

ANTIOXIDANTS (2021)

Review Pharmacology & Pharmacy

The impact of the microbiota-gut-brain axis on Alzheimer's disease pathophysiology

Tejaswini Doifode et al.

Summary: Recent studies have shown the impact of the gut microbiota on various neurodegenerative diseases, including Alzheimer's disease. Understanding the role of the microbiota may offer new targets for treatment to delay, progress, or reverse AD, as well as potentially reducing the prevalence of the disease.

PHARMACOLOGICAL RESEARCH (2021)

Review Nutrition & Dietetics

Impact of Exercise on Gut Microbiota in Obesity

Jeronimo Aragon-Vela et al.

Summary: Physical activity can help reduce inflammation and obesity progression, improve microbial variance, and maintain a healthy gut microbiota composition. However, further research is needed to fully understand the underlying mechanisms.

NUTRIENTS (2021)

Review Medicine, Research & Experimental

Therapeutic applications of mushrooms and their biomolecules along with a glimpse of in silico approach in neurodegenerative diseases

Sachchida Nand Rai et al.

Summary: The consumption of mushrooms can help prevent various neurodegenerative diseases, including Parkinson's and Alzheimer's. Medicinal mushrooms contain a variety of bioactive compounds that can reduce neurotoxicity and possess anti-cancer, anti-microbial, and antioxidant properties.

BIOMEDICINE & PHARMACOTHERAPY (2021)

Review Microbiology

Gut Microbiota Parameters Potentially Useful in Clinical Perspective

Francesco Di Pierro

Summary: Interest in gut microbiota analyses has reached a peak, as it is believed to be related to a wide range of diseases. By studying various biomarkers, potential correlations with common diseases may be observed in the microbiota.

MICROORGANISMS (2021)

Article Biochemistry & Molecular Biology

A Grape Juice Supplemented with Natural Grape Extracts Is Well Accepted by Consumers and Reduces Brain Oxidative Stress

Miriam Bobadilla et al.

Summary: Oral administration of grape juice supplemented with red grape polyphenols can exert antioxidant effects in the brains of stressed mice, which may help prevent neurodegenerative diseases.

ANTIOXIDANTS (2021)

Article Medicine, Research & Experimental

Role of microbiota-derived short-chain fatty acids in nervous system disorders

Rasoul Mirzaei et al.

Summary: Research highlights the significant impact of gut bacterial communities and their metabolites on both health and disease, particularly in maintaining metabolic balance. Gut bacterial dysbiosis can lead to pathological changes, disrupting the immune system and metabolism. Short-chain fatty acids produced through bacterial fermentation in the gut are associated with the pathophysiology of various neurological disorders.

BIOMEDICINE & PHARMACOTHERAPY (2021)

Article Chemistry, Applied

Prebiotic potential of mushroom D-glucans: implications of physicochemical properties and structural features

Andrea Caroline Ruthes et al.

Summary: Mushroom D-glucans are recognized as dietary fibers and biologically active natural polysaccharides, with various structures and physicochemical properties that may contribute to prebiotic potential. The linkage type and solubility degree of mushroom D-glucans appear to be associated with prebiotic activity outcomes. Understanding the effects of different structures and physicochemical properties in mushroom D-glucans on gut microbiota can aid in designing and selecting new prebiotics in a more predictable manner.

CARBOHYDRATE POLYMERS (2021)

Review Biochemistry & Molecular Biology

Cyanobacteria, Cyanotoxins, and Neurodegenerative Diseases: Dangerous Liaisons

Paola Sini et al.

Summary: The prevalence of neurodegenerative diseases is increasing due to longer lifespans, but the causes and mechanisms are not fully understood, and effective treatments are lacking. Genetic susceptibility and environmental factors are believed to play a role in the development of diseases like Alzheimer's and Parkinson's, with cyanotoxins produced by cyanobacteria possibly acting as important environmental triggers.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Review Microbiology

Therapeutic Properties of Edible Mushrooms and Herbal Teas in Gut Microbiota Modulation

Emanuel Vamanu et al.

Summary: Edible mushrooms and herbal teas are functional foods that interact with the human microbiota to provide health benefits. Compounds such as phenolic acids and polysaccharides in these foods play a key role in alleviating chronic diseases and combating oxidative stress, demonstrating health-promoting effects. Recent advances in utilizing plant-derived miRNAs from mushrooms and herbal teas show promise for new therapeutic effects on human health.

MICROORGANISMS (2021)

Review Medicine, Research & Experimental

The gut, its microbiome, and the brain: connections and communications Michael D. Gershon, Kara Gross Margolis

Michael D. Gershon et al.

Summary: Modern research has uncovered the complexities of gastrointestinal behavior, where the gut communicates bidirectionally with the brain and senses the environment within itself, while the microbiome within the gut also plays a significant role in this process. The microbiota-gut-brain connectome has emerged as a key aspect of this tripartite interaction, highlighting the roles of serotonin, Toll-like receptors, and macrophages in signaling.

JOURNAL OF CLINICAL INVESTIGATION (2021)

Article Rheumatology

Alteration of the gut microbiota in tumor necrosis factor-α antagonist-treated collagen-induced arthritis mice

Binglong Wang et al.

INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES (2020)

Review Nutrition & Dietetics

Relationship of Wine Consumption with Alzheimer's Disease

Marcella Reale et al.

NUTRIENTS (2020)

Article Biochemistry & Molecular Biology

The Anti-Inflammatory and Antioxidant Effects of Sodium Propionate

Alessia Filippone et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Review Biochemistry & Molecular Biology

Gut-Brain Axis and Neurodegeneration: State-of-the-Art of Meta-Omics Sciences for Microbiota Characterization

Bruno Tilocca et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Review Nutrition & Dietetics

Relationship between Wine Consumption, Diet and Microbiome Modulation in Alzheimer's Disease

M. Victoria Moreno-Arribas et al.

NUTRIENTS (2020)

Article Multidisciplinary Sciences

Glioma and temozolomide induced alterations in gut microbiome

Anthony Patrizz et al.

SCIENTIFIC REPORTS (2020)

Article Microbiology

Conversion of Rutin, a Prevalent Dietary Flavonol, by the Human Gut Microbiota

Alessandra Riva et al.

FRONTIERS IN MICROBIOLOGY (2020)

Review Biochemistry & Molecular Biology

A Review on Linking the Medicinal Functions of Mushroom Prebiotics with Gut Microbiota

Xiaoxiao Liu et al.

INTERNATIONAL JOURNAL OF MEDICINAL MUSHROOMS (2020)

Review Oncology

The role of Tannerella forsythia and Porphyromonas gingivalis in pathogenesis of esophageal cancer

Bartosz Malinowski et al.

INFECTIOUS AGENTS AND CANCER (2019)

Article Clinical Neurology

Alzheimer's Disease Including Focal Presentations

Nicolas Villain et al.

SEMINARS IN NEUROLOGY (2019)

Review Biotechnology & Applied Microbiology

Akkermansia muciniphila is a promising probiotic

Ting Zhang et al.

MICROBIAL BIOTECHNOLOGY (2019)

Review Nutrition & Dietetics

Relationship between the gut microbiome and brain function

M. Hasan Mohajeri et al.

NUTRITION REVIEWS (2018)

Article Multidisciplinary Sciences

Evidence supporting oxidative stress in a moderately affected area of the brain in Alzheimer's disease

Priscilla Youssef et al.

SCIENTIFIC REPORTS (2018)

Article Biochemistry & Molecular Biology

Agaricus bisporus supplementation reduces high-fat diet-induced body weight gain and fatty liver development

Maria Iniguez et al.

JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY (2018)

Review Neurosciences

The Emerging Evidence of the Parkinson Pandemic

E. Ray Dorsey et al.

JOURNAL OF PARKINSONS DISEASE (2018)

Article Cell Biology

Neurodegenerative Disease Transmission and Transgenesis in Mice

Brittany N. Dugger et al.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2017)

Article Multidisciplinary Sciences

Small molecules related to adrenomedullin reduce tumor burden in a mouse model of colitis-associated colon cancer

Laura Ochoa-Callejero et al.

SCIENTIFIC REPORTS (2017)

Review Medicine, General & Internal

Alzheimer's disease

Philip Scheltens et al.

LANCET (2016)

Review Biochemistry & Molecular Biology

Neurodegenerative Diseases: Might Citrus Flavonoids Play a Protective Role?

Santa Cirmi et al.

MOLECULES (2016)

Editorial Material Multidisciplinary Sciences

NEURODEGENERATIVE DISEASES

Marie-Therese Heemels

NATURE (2016)

Article Multidisciplinary Sciences

Heme Oxygenase-1 and 2 Common Genetic Variants and Risk for Multiple Sclerosis

Jose A. G. Agundez et al.

SCIENTIFIC REPORTS (2016)

Article Multidisciplinary Sciences

Mucosal adherent bacterial dysbiosis in patients with colorectal adenomas

Yingying Lu et al.

SCIENTIFIC REPORTS (2016)

Review Nutrition & Dietetics

Putative Role of Red Wine Polyphenols against Brain Pathology in Alzheimer's and Parkinson's Disease

Mario Caruana et al.

FRONTIERS IN NUTRITION (2016)

Article Medicine, General & Internal

The burden of disease in older people and implications for health policy and practice

Martin J. Prince et al.

LANCET (2015)

Review Cell Biology

Porphyromonas gingivalis Periodontal Infection and Its Putative Links with Alzheimer's Disease

Sim K. Singhrao et al.

MEDIATORS OF INFLAMMATION (2015)

Review Pharmacology & Pharmacy

A review on Alzheimer's disease pathophysiology and its management: an update

Anil Kumar et al.

PHARMACOLOGICAL REPORTS (2015)

Review Biochemistry & Molecular Biology

Reactive Oxygen Species in Inflammation and Tissue Injury

Manish Mittal et al.

ANTIOXIDANTS & REDOX SIGNALING (2014)

Article Pharmacology & Pharmacy

Role of Monocarboxylate Transporters in Drug Delivery to the Brain

Nisha Vijay et al.

CURRENT PHARMACEUTICAL DESIGN (2014)

Review Neurosciences

Therapeutics of Alzheimer's disease: Past, present and future

R. Anand et al.

NEUROPHARMACOLOGY (2014)

Article Multidisciplinary Sciences

Analysis of the Intestinal Lumen Microbiota in an Animal Model of Colorectal Cancer

Qingchao Zhu et al.

PLOS ONE (2014)

Article Multidisciplinary Sciences

Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity

Amandine Everard et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Gastroenterology & Hepatology

Quantitative Profiling of Gut Microbiota of Children With Diarrhea-Predominant Irritable Bowel Syndrome

Laura Rigsbee et al.

AMERICAN JOURNAL OF GASTROENTEROLOGY (2012)

Article Clinical Neurology

Relationship between Inflammatory Mediators, Aβ Levels and ApoE Genotype in Alzheimer Disease

M. Reale et al.

CURRENT ALZHEIMER RESEARCH (2012)

Review Biochemistry & Molecular Biology

Free radicals and antioxidants in normal physiological functions and human disease

Marian Valko et al.

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2007)