Journal
BIOMOLECULES
Volume 12, Issue 5, Pages -Publisher
MDPI
DOI: 10.3390/biom12050615
Keywords
Duguetia; essential oil; chemical composition; pharmacological activity
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Funding
- Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES, Brazil)
- Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq, Brazil)
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This study reviewed the chemical constituents and pharmacological properties of essential oils (EOs) from Duguetia species. Twelve species were found, and the main chemical constituents reported included bicyclogermacrene and humulene epoxide II. The EOs of Duguetia species exhibited anti-inflammatory, antinociceptive, antibacterial, antifungal, antioxidant, anti-trypanosoma, cytotoxic, and antitumor properties.
Duguetia A. St. Hill (Annonaceae) is recognized as one of the major genera with approximately 100 species, 67 of which are found in Brazil (29 of those are endemic). They are arboreal species with edible fruits known as pindafba, pindaiva pinha, and envira in Brazil. Many Duguetia species, in particular, have been used in traditional medicine to treat renal colic, stomachache, rheumatism, cough, toothache, muscle pain, fever, gastrointestinal pain, and breathing difficulties. In this study, we reviewed the chemical constituents and pharmacological properties of essential oils (EOs) from Duguetia species. A total of 12 species were found, along with their EO chemical constituents and bioactivities. Bicyclogermacrene, humulene epoxide II, spathulenol, germacrene D, caryophyllene oxide, viridiflorene, alpha-pinene, beta-caryophyllene, and beta-pinene were the main chemical constituents reported. The pharmacological effects of Duguetia species EOs included anti-inflammatory, antinociceptive, antibacterial, antifungal, antioxidant, anti-trypanosoma, cytotoxic and antitumor properties. This information adds to our understanding of the potential of the EOs of Duguetia species.
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