Journal
BIOMOLECULES
Volume 12, Issue 3, Pages -Publisher
MDPI
DOI: 10.3390/biom12030400
Keywords
oral squamous cell carcinoma; metabolic reprogramming; biomarker; early diagnosis; precise diagnosis
Categories
Funding
- National Natural Science Foundation of China [82173159, 82002865, 82173380, 81902759]
- Key Research and Development Projects in Jiangsu Province [BE2020628]
- Nanjing Medical Science and Technique Development Foundation [ZKX18035, YKK19091, YKK20151, QRX17083]
Ask authors/readers for more resources
The diagnosis of oral squamous cell carcinoma (OSCC) remains challenging and is associated with poor prognosis. Recent findings on altered metabolic networks in OSCC have enabled early and precise diagnosis.
The 5-year survival rate for oral squamous cell carcinoma (OSCC), one of the most common head and neck cancers, has not improved in the last 20 years. Poor prognosis of OSCC is the result of failure in early and precise diagnosis. Metabolic reprogramming, including the alteration of the uptake and utilisation of glucose, amino acids and lipids, is an important feature of OSCC and can be used to identify its biomarkers for early and precise diagnosis. In this review, we summarise how recent findings of rewired metabolic networks in OSCC have facilitated early and precise diagnosis of OSCC.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
