Related references
Note: Only part of the references are listed.Salvianolic acid A suppresses CCl4-induced liver fibrosis through regulating the Nrf2/HO-1, NF-κB/IκBα, p38 MAPK, and JAK1/STAT3 signaling pathways
Shengnan Li et al.
DRUG AND CHEMICAL TOXICOLOGY (2023)
Adverse renal effects of NLRP3 inflammasome inhibition by MCC950 in an interventional model of diabetic kidney disease
Jakob A. Ostergaard et al.
CLINICAL SCIENCE (2022)
Simultaneous Modulation of NLRP3 Inflammasome and Nrf2/ARE Pathway Rescues Thioacetamide-Induced Hepatic Damage in Mice: Role of Oxidative Stress and Inflammation
Durgesh Kumar Dwivedi et al.
INFLAMMATION (2022)
TGF-beta activates NLRP3 inflammasome by an autocrine production of TGF-beta in LX-2 human hepatic stellate cells
Hwansu Kang et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2022)
Gut bacterial metabolite Urolithin A inhibits myocardial fibrosis through activation of Nrf2 pathway in vitro and in vivo
Pengfei Chen et al.
MOLECULAR MEDICINE (2022)
Induction of Pro-Fibrotic CLIC4 in Dermal Fibroblasts by TGF-β/Wnt3a Is Mediated by GLI2 Upregulation
Christopher W. Wasson et al.
CELLS (2022)
Glibenclamide alleviates beta adrenergic receptor activation-induced cardiac inflammation
Ning Cao et al.
ACTA PHARMACOLOGICA SINICA (2022)
HDAC3 promotes pulmonary fibrosis by activating NOTCH1 and STAT1 signaling and up-regulating inflammasome components AIM2 and ASC
Qing Zheng et al.
CYTOKINE (2022)
VX-765 ameliorates renal injury and fibrosis in diabetes by regulating caspase-1-mediated pyroptosis and inflammation
Si Wen et al.
JOURNAL OF DIABETES INVESTIGATION (2022)
Self-Assembled Human Skin Equivalents Model Macrophage Activation of Cutaneous Fibrogenesis in Systemic Sclerosis
Mengqi Huang et al.
ARTHRITIS & RHEUMATOLOGY (2022)
1-Deoxysphingolipids cause autophagosome and lysosome accumulation and trigger NLRP3 inflammasome activation
Mario A. Lauterbach et al.
AUTOPHAGY (2021)
The covalent NLRP3-inflammasome inhibitor Oridonin relieves myocardial infarction induced myocardial fibrosis and cardiac remodeling in mice
Ri-Feng Gao et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2021)
β-Hydroxybutyrate inhibits cardiac microvascular collagen 4 accumulation by attenuating oxidative stress in streptozotocin-induced diabetic rats and high glucose treated cells
Huanli Qi et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2021)
STIM1 mediates IAV-induced inflammation of lung epithelial cells by regulating NLRP3 and inflammasome activation via targeting miR-223
Cui-Cui Liu et al.
LIFE SCIENCES (2021)
MiR-146a-5p Mimic Inhibits NLRP3 Inflammasome Downstream Inflammatory Factors and CLIC4 in Neonatal Necrotizing Enterocolitis
Jianglong Chen et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)
Liproxstatin-1 alleviates bleomycin-induced alveolar epithelial cells injury and mice pulmonary fibrosis via attenuating inflammation, reshaping redox equilibrium, and suppressing ROS/p53/α-SMA pathway
Ningning Tao et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2021)
Shenkang Injection and Its Three Anthraquinones Ameliorates Renal Fibrosis by Simultaneous Targeting IκB/NF-κB and Keap1/Nrf2 Signaling Pathways
Liang-Pu Luo et al.
FRONTIERS IN PHARMACOLOGY (2021)
NLRC5 Deficiency Deregulates Hepatic Inflammatory Response but Does Not Aggravate Carbon Tetrachloride-Induced Liver Fibrosis
Akouavi Julite I. Quenum et al.
FRONTIERS IN IMMUNOLOGY (2021)
The ASC Speck and NLRP3 Inflammasome Function Are Spatially and Temporally Distinct
Abhinit Nagar et al.
FRONTIERS IN IMMUNOLOGY (2021)
Bile Acids Activate NLRP3 Inflammasome, Promoting Murine Liver Inflammation or Fibrosis in a Cell Type-Specific Manner
Theresa Maria Holtmann et al.
CELLS (2021)
Enterococcus Faecalis activates NLRP3 inflammasomes leading to increased interleukin-1 beta secretion and pyroptosis of THP-1 macrophages
Shujun Ran et al.
MICROBIAL PATHOGENESIS (2021)
Cardioprotective Roles of β-Hydroxybutyrate Against Doxorubicin Induced Cardiotoxicity
Yihai Liu et al.
FRONTIERS IN PHARMACOLOGY (2021)
Interleukin-1RA Mitigates SARS-CoV-2-Induced Inflammatory Lung Vascular Leakage and Mortality in Humanized K18-hACE-2 Mice
Shiqin Xiong et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2021)
UPR attenuates the proinflammatory effect of HPDLF on macrophage polarization
Yuting Shen et al.
CELL STRESS & CHAPERONES (2021)
Anti-Inflammatory Effect of Allicin Associated with Fibrosis in Pulmonary Arterial Hypertension
Jose L. Sanchez-Gloria et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
Pulmonary Stretch and Lung Mechanotransduction: Implications for Progression in the Fibrotic Lung
Alessandro Marchioni et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
Crocin alleviates the inflammation and oxidative stress responses associated with diabetic nephropathy in rats via NLRP3 inflammasomes
Linjuan Zhang et al.
LIFE SCIENCES (2021)
Sensing low intracellular potassium by NLRP3 results in a stable open structure that promotes inflammasome activation
Ana Tapia-Abellan et al.
SCIENCE ADVANCES (2021)
The Roles of Various Prostaglandins in Fibrosis: A Review
Ke Li et al.
BIOMOLECULES (2021)
Deubiquitination and Activation of the NLRP3 Inflammasome by UCHL5 in HCV-Infected Cells
Akshaya Ramachandran et al.
MICROBIOLOGY SPECTRUM (2021)
Interleukin-1 and Transforming Growth Factor Beta: Commonly Opposing, but Sometimes Supporting, Master Regulators of the Corneal Wound Healing Response to Injury
Steven E. Wilson
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2021)
The Role of KCNMB1 and BK Channels in Myofibroblast Differentiation and Pulmonary Fibrosis
Anne M. Scruggs et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2020)
Calcium -Sensing Receptor on Neutrophil Promotes Myocardial Apoptosis and Fibrosis After Acute Myocardial Infarction via NLRP3 In flammasome Activation
Ziqi Ren et al.
CANADIAN JOURNAL OF CARDIOLOGY (2020)
Total Absence of Dystrophin Expression Exacerbates Ectopic Myofiber Calcification and Fibrosis and Alters Macrophage Infiltration Patterns
Christopher N. J. Young et al.
AMERICAN JOURNAL OF PATHOLOGY (2020)
H2S alleviates renal injury and fibrosis in response to unilateral ureteral obstruction by regulating macrophage infiltration via inhibition of NLRP3 signaling
Yueyuan Zhou et al.
EXPERIMENTAL CELL RESEARCH (2020)
SUMO1 SUMOylates and SENP3 deSUMOylates NLRP3 to orchestrate the inflammasome activation
Luyao Shao et al.
FASEB JOURNAL (2020)
Parthenolide, an NF-κB inhibitor, alleviates peritoneal fibrosis by suppressing the TGF-β/Smad pathway
Ying Zhang et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2020)
NLRP3-associated autoinflammatory diseases: Phenotypic and molecular characteristics of germline versus somatic mutations
Camille Louvrier et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2020)
Ventilatory support and mechanical properties of the fibrotic lung acting as a squishy ball
Alessandro Marchioni et al.
ANNALS OF INTENSIVE CARE (2020)
Brucella abortus Infection Elicited Hepatic Stellate Cell-Mediated Fibrosis Through Inflammasome-Dependent IL-1β Production
Paula Constanza Arriola Benitez et al.
FRONTIERS IN IMMUNOLOGY (2020)
The Role of NLRP3 Inflammasome Activation in the Epithelial to Mesenchymal Transition Process During the Fibrosis
Amani Abraheem Alsadiq Alyaseer et al.
FRONTIERS IN IMMUNOLOGY (2020)
NLRC5 deficiency ameliorates cardiac fibrosis in diabetic cardiomyopathy by regulating EndMT through Smad2/3 signaling pathway
Bo Wang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2020)
NEK7 mediated assembly and activation of NLRP3 inflammasome downstream of potassium efflux in ventilator-induced lung injury
Huan Liu et al.
BIOCHEMICAL PHARMACOLOGY (2020)
Original Protection against renal ischemia and reperfusion injury by short-term time-restricted feeding involves the mitochondrial unfolded protein response
Pedro Rojas-Morales et al.
FREE RADICAL BIOLOGY AND MEDICINE (2020)
The Immunomodulatory Metabolite Itaconate Modifies NLRP3 and Inhibits Inflammasome Activation
Alexander Hooftman et al.
CELL METABOLISM (2020)
Cell-Type Transcriptome Atlas of Human Aortic Valves Reveal Cell Heterogeneity and Endothelial to Mesenchymal Transition Involved in Calcific Aortic Valve Disease
Kang Xu et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2020)
Parvovirus B19 activates in vitro normal human dermal fibroblasts: a possible implication in skin fibrosis and systemic sclerosis
Rosaria Arvia et al.
RHEUMATOLOGY (2020)
Natural Products that Target the NLRP3 Inflammasome to Treat Fibrosis
Nan Ding et al.
FRONTIERS IN PHARMACOLOGY (2020)
Reactive Oxygen Species Interact With NLRP3 Inflammasomes and Are Involved in the Inflammation of Sepsis: From Mechanism to Treatment of Progression
Shuai Zhao et al.
FRONTIERS IN PHYSIOLOGY (2020)
Interleukin-1β Modulation of the Mechanobiology of Primary Human Pulmonary Fibroblasts: Potential Implications in Lung Repair
Marta Gabasa et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Tranilast Inhibits Pulmonary Fibrosis by Suppressing TGF beta/SMAD2 Pathway
Motoyasu Kato et al.
DRUG DESIGN DEVELOPMENT AND THERAPY (2020)
Angiotensin (1-7) inhibits arecoline-induced migration and collagen synthesis in human oral myofibroblasts via inhibiting NLRP3 inflammasome activation
Yuehua You et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2019)
Calcitriol inhibits ROS-NLRP3-IL-1β signaling axis via activation of Nrf2-antioxidant signaling in hyperosmotic stress stimulated human corneal epithelial cells
Yiqin Dai et al.
REDOX BIOLOGY (2019)
Interleukin-18 promotes fibroblast senescence in pulmonary fibrosis through down-regulating Klotho expression
Li-Ming Zhang et al.
BIOMEDICINE & PHARMACOTHERAPY (2019)
The selective NLRP3 inflammasome inhibitor MCC950 alleviates cholestatic liver injury and fibrosis in mice
Junwen Qu et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2019)
Oridonin protects against cardiac hypertrophy by promoting P21-related autophagy
Man Xu et al.
CELL DEATH & DISEASE (2019)
IL-1 receptor blockade skews inflammation towards Th2 in a mouse model of systemic sclerosis
Anna Birnhuber et al.
EUROPEAN RESPIRATORY JOURNAL (2019)
NLRP3 inflammasome inhibition attenuates cisplatin-induced renal fibrosis by decreasing oxidative stress and inflammation
Shu Li et al.
EXPERIMENTAL CELL RESEARCH (2019)
Propofol directly induces caspase-1-dependent macrophage pyroptosis through the NLRP3-ASC inflammasome
Lingbin Sun et al.
CELL DEATH & DISEASE (2019)
NLRP6 deficiency aggravates liver injury after allogeneic hematopoietic stem cell transplantation
Mingfeng Li et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2019)
Potential Role of Extracellular ATP Released by Bacteria in Bladder Infection and Contractility
Behnam Abbasian et al.
MSPHERE (2019)
A small molecule inhibitor MCC950 ameliorates kidney injury in diabetic nephropathy by inhibiting NLRP3 inflammasome activation
CongXiao Zhang et al.
DIABETES METABOLIC SYNDROME AND OBESITY-TARGETS AND THERAPY (2019)
Neutralization of IL-18 by IL-18 binding protein ameliorates bleomycin-induced pulmonary fibrosis via inhibition of epithelial-mesenchymal transition
Li-Ming Zhang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2019)
The Regulation of Skin Fibrosis in Systemic Sclerosis by Extracellular ATP via P2Y2 Purinergic Receptor
Liyanage Manosika Buddhini Perera et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2019)
NLRP3 inflammasome activation from Kupffer cells is involved in liver fibrosis of Schistosoma japonicum-infected mice via NF-κB
Wen-Juan Zhang et al.
PARASITES & VECTORS (2019)
Prostaglandin E2 inhibits profibrotic function of human pulmonary fibroblasts by disrupting Ca2+ signaling
Subhendu Mukherjee et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2019)
Eplerenone Ameliorates Cell Pyroptosis in Contralateral Kidneys of Rats with Unilateral Ureteral Obstruction
Xuelian Ma et al.
NEPHRON (2019)
Inhibition of IL-18 reduces renal fibrosis after ischemia-reperfusion
Hua Liang et al.
BIOMEDICINE & PHARMACOTHERAPY (2018)
Nuclear Localization Leucine-Rich-Repeat Protein 1 Deficiency Protects Against Cardiac Hypertrophy by Pressure Overload
Jing Zong et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2018)
Knockdown of NLRC5 inhibits renal fibroblast activation via modulating TGF-beta 1/Smad signaling pathway
Shiying Wang et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2018)
Effects of NLRP6 on the proliferation and activation of human hepatic stellate cells
Yiming Zhu et al.
EXPERIMENTAL CELL RESEARCH (2018)
Consequences of Epithelial Inflammasome Activation by Bacterial Pathogens
Mikael E. Sellin et al.
JOURNAL OF MOLECULAR BIOLOGY (2018)
Antifibrosis Effect of Novel Oridonin Analog CYD0618 Via Suppression of the NF-κB Pathway
Claire B. Cummins et al.
JOURNAL OF SURGICAL RESEARCH (2018)
OLT1177, a ß-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation
Carlo Marchetti et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
The KCa3.1 blocker TRAM-34 inhibits proliferation of fibroblasts in paraquat-induced pulmonary fibrosis
Hui Xie et al.
TOXICOLOGY LETTERS (2018)
IL-1-IL-17 Signaling Axis Contributes to Fibrosis and Inflammation in Two Different Murine Models of Systemic Sclerosis
Min-Jung Park et al.
FRONTIERS IN IMMUNOLOGY (2018)
Ca2+-Activated K+ Channel KCa3.1 as a Therapeutic Target for Immune Disorders
Susumu Ohya et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2018)
NLRP3 inflammasome activation and lung fibrosis caused by airborne fine particulate matter
Runxiao Zheng et al.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2018)
NLRP1 promotes TGF-1-induced myofibroblast differentiation in neonatal rat cardiac fibroblasts
Jing Zong et al.
JOURNAL OF MOLECULAR HISTOLOGY (2018)
SUMO-mediated regulation of NLRP3 modulates inflammasome activity
Rachael Barry et al.
NATURE COMMUNICATIONS (2018)
IL-6 augments IL-4-induced polarization of primary human macrophages through synergy of STAT3, STAT6 and BATF transcription factors
Sahil Gupta et al.
ONCOIMMUNOLOGY (2018)
Oridonin Inhibits Myofibroblast Differentiation and Bleomycin-induced Pulmonary Fibrosis by Regulating Transforming Growth Factor β(TGFβ)/Smad Pathway
Yu Fu et al.
MEDICAL SCIENCE MONITOR (2018)
Parthenolide attenuated bleomycin-induced pulmonary fibrosis via the NF-κB/Snail signaling pathway
Xiao-he Li et al.
RESPIRATORY RESEARCH (2018)
Small-conductance Ca2+-activated K+ channels: insights into their roles in cardiovascular disease
Mingxia Gu et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2018)
The transcription factor GLI2 as a downstream mediator of transforming growth factor-β-induced fibroblast activation in SSc
Ruifang Liang et al.
ANNALS OF THE RHEUMATIC DISEASES (2017)
Sirtuin 3 Deregulation Promotes Pulmonary Fibrosis
Meredith L. Sosulski et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2017)
Transforming growth factor β-inhibitor Repsox downregulates collagen expression of scleroderma dermal fibroblasts and prevents bleomycin-induced mice skin fibrosis
Maho Ide et al.
EXPERIMENTAL DERMATOLOGY (2017)
KCa1.1 channels regulate β1-integrin function and cell adhesion in rheumatoid arthritis fibroblast-like synoviocytes
Mark R. Tanner et al.
FASEB JOURNAL (2017)
The intracellular chloride channel proteins CLIC1 and CLIC4 induce IL-1β transcription and activate the NLRP3 inflammasome
Raquel Domingo-Fernandez et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
A voltage-dependent K+ channel in the lysosome is required for refilling lysosomal Ca2+ stores
Wuyang Wang et al.
JOURNAL OF CELL BIOLOGY (2017)
NLRP3 inflammasome assembly is regulated by phosphorylation of the pyrin domain
Andrea Stutz et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2017)
Protein kinase D at the Golgi controls NLRP3 inflammasome activation
Zhirong Zhang et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2017)
NLRP3 Phosphorylation Is an Essential Priming Event for Inflammasome Activation
Nan Song et al.
MOLECULAR CELL (2017)
NLRC5 silencing ameliorates cardiac fibrosis by inhibiting the TGF-β1/Smad3 signaling pathway
Hongtao Zhou et al.
MOLECULAR MEDICINE REPORTS (2017)
Anakinra reduces blood pressure and renal fibrosis in one kidney/DOCA/salt-induced hypertension
Yeong Hann Ling et al.
PHARMACOLOGICAL RESEARCH (2017)
TMEM175 deficiency impairs lysosomal and mitochondrial function and increases α-synuclein aggregation
Sarah Jinn et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
CLICs-dependent chloride efflux is an essential and proximal upstream event for NLRP3 inflammasome activation
Tiantian Tang et al.
NATURE COMMUNICATIONS (2017)
Protective and therapeutic effect of felodipine against bleomycin-induced pulmonary fibrosis in mice
Ken-ichiro Tanaka et al.
SCIENTIFIC REPORTS (2017)
Enhanced store-operated Ca2+ influx and ORAI1 expression in ventricular fibroblasts from human failing heart
Gracious R. Ross et al.
BIOLOGY OPEN (2017)
The P2X7 Receptor Mediates Toxoplasma gondii Control in Macrophages through Canonical NLRP3 Inflammasome Activation and Reactive Oxygen Species Production
Aline Cristina Abreu Moreira-Souza et al.
FRONTIERS IN IMMUNOLOGY (2017)
The antiviral drug tenofovir, an inhibitor of Pannexin-1-mediated ATP release, prevents liver and skin fibrosis by downregulating adenosine levels in the liver and skin
Jessica L. Feig et al.
PLOS ONE (2017)
Pro-inflammatory Ca++-activated K+ channels are inhibited by hydroxychloroquine
Maria Eugenia Schroeder et al.
SCIENTIFIC REPORTS (2017)
Nuclear Factor E2-Related Factor-2 Negatively Regulates NLRP3 Inflammasome Activity by Inhibiting Reactive Oxygen Species-Induced NLRP3 Priming
Xiuting Liu et al.
ANTIOXIDANTS & REDOX SIGNALING (2017)
Bladder fibrosis during outlet obstruction is triggered through the NLRP3 inflammasome and the production of IL-1β
Francis M. Hughes et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2017)
Mir-155 is overexpressed in systemic sclerosis fibroblasts and is required for NLRP3 inflammasome-mediated collagen synthesis during fibrosis
Carol M. Artlett et al.
ARTHRITIS RESEARCH & THERAPY (2017)
NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component
Hexin Shi et al.
NATURE IMMUNOLOGY (2016)
Silencing NLRC5 inhibits extracellular matrix expression in keloid fibroblasts via inhibition of transforming growth factor-β1/Smad signaling pathway
Hai-Li Ma et al.
BIOMEDICINE & PHARMACOTHERAPY (2016)
Nod-like receptor protein 3 inflammasome activation by Escherichia coli RNA induces transforming growth factor beta 1 secretion in hepatic stellate cells
Hui Wang et al.
BOSNIAN JOURNAL OF BASIC MEDICAL SCIENCES (2016)
Interleukin-18 deficiency protects against renal interstitial fibrosis in aldosterone/salt-treated mice
Akiko Tanino et al.
CLINICAL SCIENCE (2016)
Reassessing the Role of the Active TGF-β1 as a Biomarker in Systemic Sclerosis: Association of Serum Levels with Clinical Manifestations
Andrea Tavares Dantas et al.
DISEASE MARKERS (2016)
NLRC5 regulates TGF-β1-induced proliferation and activation of hepatic stellate cells during hepatic fibrosis
Tao Xu et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2016)
Fluorofenidone attenuates pulmonary inflammation and fibrosis via inhibiting the activation of NALP3 inflammasome and IL-1/IL-1R1/MyD88/NF-B pathway
Cheng Song et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2016)
NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22
Marianne R. Spalinger et al.
JOURNAL OF CLINICAL INVESTIGATION (2016)
An NLRP3-specific inflammasome inhibitor attenuates crystal-induced kidney fibrosis in mice
Isis Ludwig-Portugall et al.
KIDNEY INTERNATIONAL (2016)
Metformin and resveratrol inhibit Drp1-mediated mitochondrial fission and prevent ER stress-associated NLRP3 inflammasome activation in the adipose tissue of diabetic mice
Aiyun Li et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2016)
NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux
Yuan He et al.
NATURE (2016)
Role of NLRC5 in progression and reversal of hepatic fibrosis
Xuejiao Liu et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2016)
The accumulation of macrophages attenuates the effect of recombinant human endostatin on lung cancer
Yanyang Liu et al.
ONCOTARGETS AND THERAPY (2016)
IL-1 receptor antagonist ameliorates inflammasome-dependent inflammation in murine and human cystic fibrosis
Rossana G. Iannitti et al.
NATURE COMMUNICATIONS (2016)
The E3 ubiquitin ligase TRIM31 attenuates NLRP3 inflammasome activation by promoting proteasomal degradation of NLRP3
Hui Song et al.
NATURE COMMUNICATIONS (2016)
TGF-β induces M2-like macrophage polarization via SNAIL-mediated suppression of a pro-inflammatory phenotype
Fan Zhang et al.
ONCOTARGET (2016)
The calcium-activated potassium channel KCa3.1 is an important modulator of hepatic injury
Linda Sevelsted Moller et al.
SCIENTIFIC REPORTS (2016)
Pleural inhibition of the caspase-1/IL-1β pathway diminishes profibrotic lung toxicity of bleomycin
Olivier Burgy et al.
RESPIRATORY RESEARCH (2016)
DAMPs as mediators of sterile inflammation in aging-related pathologies
Noa Feldman et al.
AGEING RESEARCH REVIEWS (2015)
Calcium Homeostasis and Ionic Mechanisms in Pulmonary Fibroblasts
Luke J. Janssen et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2015)
Disruption of Calcium Signaling in Fibroblasts and Attenuation of Bleomycin-Induced Fibrosis by Nifedipine
Subhendu Mukherjee et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2015)
Therapeutic Opportunities in Damage-Associated Molecular Pattern-Driven Metabolic Diseases
Irma Garcia-Martinez et al.
ANTIOXIDANTS & REDOX SIGNALING (2015)
Lipopolysaccharide Primes the NALP3 Inflammasome by Inhibiting Its Ubiquitination and Degradation Mediated by the SCFFBXL2 E3 Ligase
SeungHye Han et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
The role of KCa3.1 channels in cardiac fibrosis induced by pressure overload in rats
Li-Mei Zhao et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2015)
β-amyloid, microglia, and the inflammasome in Alzheimer's disease
Maike Gold et al.
SEMINARS IN IMMUNOPATHOLOGY (2015)
K+ regulates Ca2+ to drive inflammasome signaling: dynamic visualization of ion flux in live cells
J. R. Yaron et al.
CELL DEATH & DISEASE (2015)
Targeting the unfolded protein response, XBP1, and the NLRP3 inflammasome in fibrosis and cancer
Beth Overley-Adamson et al.
CANCER BIOLOGY & THERAPY (2014)
Cytosolic Double-Stranded RNA Activates the NLRP3 Inflammasome via MAVS-Induced Membrane Permeabilization and K+ Efflux
Luigi Franchi et al.
JOURNAL OF IMMUNOLOGY (2014)
KCa3.1 mediates activation of fibroblasts in diabetic renal interstitial fibrosis
Chunling Huang et al.
NEPHROLOGY DIALYSIS TRANSPLANTATION (2014)
Interleukin-1β Attenuates Myofibroblast Formation and Extracellular Matrix Production in Dermal and Lung Fibroblasts Exposed to Transforming Growth Factor-β1
Masum M. Mia et al.
PLOS ONE (2014)
Glibenclamide improves kidney and heart structure and function in the adenine-diet model of chronic kidney disease
Vishal Diwan et al.
PHARMACOLOGICAL RESEARCH (2014)
Inflammasome activation leads to Caspase-1-dependent mitochondrial damage and block of mitophagy
Jiujiu Yu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Interstitial lung diseases induced or exacerbated by DMARDS and biologic agents in rheumatoid arthritis: A systematic literature review
Camille Roubille et al.
SEMINARS IN ARTHRITIS AND RHEUMATISM (2014)
Calcium signaling and mitochondrial destabilization in the triggering of the NLRP3 inflammasome
Tiffany Horng
TRENDS IN IMMUNOLOGY (2014)
Caspase-11 Controls Interleukin-1β Release through Degradation of TRPC1
Benedicte F. Py et al.
CELL REPORTS (2014)
Correction: Malarial Hemozoin Activates the NLRP3 Inflammasome through Lyn and Syk Kinases
Marina Tiemi Shio et al.
PLoS Pathogens (2014)
Tranilast administration reduces fibrosis and improves fatigue resistance in muscles of mdx dystrophic mice
Kristy Swiderski et al.
FIBROGENESIS & TISSUE REPAIR (2014)
Pirfenidone Attenuates Cardiac Fibrosis in a Mouse Model of TAC-Induced Left Ventricular Remodeling by Suppressing NLRP3 Inflammasome Formation
Yongliang Wang et al.
CARDIOLOGY (2013)
Upregulated NLRP3 Inflammasome Activation in Patients With Type 2 Diabetes
Hye-Mi Lee et al.
DIABETES (2013)
K+ Efflux Is the Common Trigger of NLRP3 Inflammasome Activation by Bacterial Toxins and Particulate Matter
Raul Munoz-Planillo et al.
IMMUNITY (2013)
Platelet derived growth factor-evoked Ca2+ wave and matrix gene expression through phospholipase C in human pulmonary fibroblast
Subhendu Mukherjee et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2013)
Mitochondrial Reactive Oxygen Species Induces NLRP3-Dependent Lysosomal Damage and Inflammasome Activation
Michelle E. Heid et al.
JOURNAL OF IMMUNOLOGY (2013)
Targeting Potassium Channels Kv1.3 and KCa3.1: Routes to Selective Immunomodulators in Autoimmune Disorder Treatment?
Jun Wang et al.
PHARMACOTHERAPY (2013)
Transforming Growth Factor-β Evokes Ca2+ Waves and Enhances Gene Expression in Human Pulmonary Fibroblasts
Subhendu Mukherjee et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2012)
Interleukin-18 system plays an important role in keloid pathogenesis via epithelial-mesenchymal interactions
D. V. Do et al.
BRITISH JOURNAL OF DERMATOLOGY (2012)
Parthenolide-induced apoptosis of hepatic stellate cells and anti-fibrotic effects in an in vivo rat model
In Hee Kim et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2012)
Inflammasome Activators Induce Interleukin-1α Secretion via Distinct Pathways with Differential Requirement for the Protease Function of Caspase-1
Olaf Gross et al.
IMMUNITY (2012)
IL1RN genetic variations and risk of IPF: a meta-analysis and mRNA expression study
Nicoline M. Korthagen et al.
IMMUNOGENETICS (2012)
Non-transcriptional Priming and Deubiquitination Regulate NLRP3 Inflammasome Activation
Christine Juliana et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP
Geun-Shik Lee et al.
NATURE (2012)
Critical role for calcium mobilization in activation of the NLRP3 inflammasome
Tomohiko Murakami et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Modelling the interaction of keratinocytes and fibroblasts during normal and abnormal wound healing processes
Shakti N. Menon et al.
PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2012)
Extracellular Ca2+ is a danger signal activating the NLRP3 inflammasome through G protein-coupled calcium sensing receptors
Manuela Rossol et al.
NATURE COMMUNICATIONS (2012)
The Inflammasome Activating Caspase 1 Mediates Fibrosis and Myofibroblast Differentiation in Systemic Sclerosis
Carol M. Artlett et al.
ARTHRITIS AND RHEUMATISM (2011)
Genetic variability in the IL1RN gene and the balance between interleukin (IL)-1 receptor agonist and IL-1β in idiopathic pulmonary fibrosis
N. P. Barlo et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2011)
Mite allergen is a danger signal for the skin via activation of inflammasome in keratinocytes
Xiuju Dai et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2011)
Interleukin-1β Induces Increased Transcriptional Activation of the Transforming Growth Factor-β-activating Integrin Subunit β8 through Altering Chromatin Architecture
Jennifer A. Markovics et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Caspase-1-Processed Cytokines IL-1β and IL-18 Promote IL-17 Production by γδ and CD4 T Cells That Mediate Autoimmunity
Stephen J. Lalor et al.
JOURNAL OF IMMUNOLOGY (2011)
Innate immunity and monocyte-macrophage activation in atherosclerosis
Joseph Shalhoub et al.
JOURNAL OF INFLAMMATION-LONDON (2011)
A role for mitochondria in NLRP3 inflammasome activation
Rongbin Zhou et al.
NATURE (2011)
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
Kiichi Nakahira et al.
NATURE IMMUNOLOGY (2011)
Inhibitory Effects of T/L-type Calcium Channel Blockers on Tubulointerstitial Fibrosis in Obstructed Kidneys in Rats
Hirohisa Matsuda et al.
UROLOGY (2011)
Clinical Benefits of Intra-articular Anakinra for Persistent Knee Effusion
Christopher Brown et al.
Journal of Knee Surgery (2011)
Incidence and Mortality of Interstitial Lung Disease in Rheumatoid Arthritis
Tim Bongartz et al.
ARTHRITIS AND RHEUMATISM (2010)
Rationale and efficacy of interleukin-1 targeting in Erdheim-Chester disease
Achille Aouba et al.
BLOOD (2010)
Topical tranilast for treatment of the early stage of mild dry eye associated with chronic GVHD
Y. Ogawa et al.
BONE MARROW TRANSPLANTATION (2010)
Calcium-activated potassium channels - a therapeutic target for modulating nitric oxide in cardiovascular disease?
Thomas Dalsgaard et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2010)
BAY 11-7082, a Nuclear Factor-κB Inhibitor, Reduces Inflammation and Apoptosis in a Rat Cardiac Ischemia-Reperfusion Injury Model
Yong Sook Kim et al.
INTERNATIONAL HEART JOURNAL (2010)
The Role of Potassium in Inflammasome Activation by Bacteria
Cecilia S. Lindestam Arlehamn et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Bleomycin and IL-1β-mediated pulmonary fibrosis is IL-17A dependent
Mark S. Wilson et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2010)
Thioredoxin-interacting protein links oxidative stress to inflammasome activation
Rongbin Zhou et al.
NATURE IMMUNOLOGY (2010)
Clinical Benefits of Intra-articular Anakinra for Arthrofibrosis
Christopher A. Brown et al.
ORTHOPEDICS (2010)
Disruption of Interleukin-1 Signaling Improves the Quality of Wound Healing
Alan A. Thomay et al.
AMERICAN JOURNAL OF PATHOLOGY (2009)
Inflammasome-mediated regulation of hepatic stellate cells
Azuma Watanabe et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2009)
Uric Acid Is a Danger Signal Activating NALP3 Inflammasome in Lung Injury Inflammation and Fibrosis
Pamela Gasse et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2009)
Ectopic Calcification is Caused by Elevated Levels of Serum Inorganic Phosphate in Mdx Mice
Namiko Kikkawa et al.
CELL STRUCTURE AND FUNCTION (2009)
Mitochondria and reactive oxygen species
Alicia J. Kowaltowski et al.
FREE RADICAL BIOLOGY AND MEDICINE (2009)
The Intracellular Sensor NLRP3 Mediates Key Innate and Healing Responses to Influenza A Virus via the Regulation of Caspase-1
Paul G. Thomas et al.
IMMUNITY (2009)
Glyburide inhibits the Cryopyrin/Nalp3 inflammasome
Mohamed Lamkanfi et al.
JOURNAL OF CELL BIOLOGY (2009)
IL-1R1/MyD88 Signaling Is Critical for Elastase-Induced Lung Inflammation and Emphysema
Isabelle Couillin et al.
JOURNAL OF IMMUNOLOGY (2009)
1-Peptidyl-2-arachidonoyl-3-stearoyl-sn-glyceride: An Immunologically Active Lipopeptide from Goat Serum (Capra hircus) Is an Endogenous Damage-Associated Molecular Pattern
James D. Thacker et al.
JOURNAL OF NATURAL PRODUCTS (2009)
IL-18 neutralization ameliorates obstruction-induced epithelial-mesenchymal transition and renal fibrosis
Ahmad H. Bani-Hani et al.
KIDNEY INTERNATIONAL (2009)
Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence
Olaf Gross et al.
NATURE (2009)
Interleukin-1 beta regulates proximal tubular cell transforming growth factor beta-1 signalling
Dong Dong Luo et al.
NEPHROLOGY DIALYSIS TRANSPLANTATION (2009)
CLIC4 mediates TGF-beta 1-induced fibroblast-to-myofibroblast transdifferentiation in ovarian cancer
Qin Yao et al.
ONCOLOGY REPORTS (2009)
Renal fibrosis is attenuated by targeted disruption of KCa3.1 potassium channels
Ivica Grgic et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
TGF-β1 induced epithelial to mesenchymal transition (EMT) in human bronchial epithelial cells is enhanced by IL-1β but not abrogated by corticosteroids
Astrid M. Doerner et al.
RESPIRATORY RESEARCH (2009)
Role of interleukin-6 in bleomycin-induced lung inflammatory changes in mice
Fumitake Saito et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2008)
Active caspase-1 is a regulator of unconventional protein secretion
Martin Keller et al.
CELL (2008)
IL-1, IL-18, and IL-33 families of cytokines
William P. Arend et al.
IMMUNOLOGICAL REVIEWS (2008)
Myofibroblast communication is controlled by intercellular mechanical coupling
Lysianne Follonier et al.
JOURNAL OF CELL SCIENCE (2008)
Hepatic stellate cells: Protean, multifunctional, and enigmatic cells of the liver
Scott L. Friedman
PHYSIOLOGICAL REVIEWS (2008)
The Nalp3 inflammasome is essential for the development of silicosis
Suzanne L. Cassel et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica
Catherine Dostert et al.
SCIENCE (2008)
The inflammasome:: a danger sensing complex triggering innate immunity
Virginie Petrilli et al.
CURRENT OPINION IN IMMUNOLOGY (2007)
IL-1R1/MyD88 signaling and the inflammasome are essential in pulmonary inflammation and fibrosis in mice
Pamela Gasse et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Microarray-based identification of novel biomarkers in IL-1-mediated diseases
Florence Allantaz et al.
CURRENT OPINION IN IMMUNOLOGY (2007)
Ebselen reduces nitration and restores voltage-gated potassium channel function in small coronary arteries of diabetic rats
Aaron H. Bubolz et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2007)
Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration
V. Petrilli et al.
CELL DEATH AND DIFFERENTIATION (2007)
The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation
T. Fernandes-Alnemri et al.
CELL DEATH AND DIFFERENTIATION (2007)
The inflammasome mediates UVB-Induced activation and secretion of interleukin-1β by keratinocytes
Laurence Feldmeyer et al.
CURRENT BIOLOGY (2007)
ATP activates a reactive oxygen species-dependent oxidative stress response and secretion of proinflammatory cytokines in macrophages
Cristiane M. Cruz et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Inflammatory cytokines induce the transformation of human dermal microvascular endothelial cells into myofibroblasts: a potential role in skin fibrogenesis
V. Chaudhuri et al.
JOURNAL OF CUTANEOUS PATHOLOGY (2007)
Safety of extended treatment with anakinra in patients with rheumatoid arthritis
R. M. Fleischmann et al.
ANNALS OF THE RHEUMATIC DISEASES (2006)
Gout-associated uric acid crystals activate the NALP3 inflammasome
F Martinon et al.
NATURE (2006)
Stress deprivation simultaneously induces over-expression of interleukin-lbeta, tumor necrosis factor-alpha, and transforming growth factor-beta in fibroblasts and mechanical deterioration of the tissue in the patellar tendone
H Uchida et al.
JOURNAL OF BIOMECHANICS (2005)
Transplantation of skeletal myoblasts secreting an IL-1 inhibitor modulates adverse remodeling in infarcted murine myocardium
B Murtuza et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Correlation of cell necrosis and tissue calcification with ischemia/reperfusion injury after liver transplantation
GN Tzimas et al.
TRANSPLANTATION PROCEEDINGS (2004)
Mediation of interleukin-1β-induced transforming growth factor β1 expression by activator protein 4 transcription factor in primary cultures of bovine articular chondrocytes -: Possible cooperation with activator protein 1
R Andriamanalijaona et al.
ARTHRITIS AND RHEUMATISM (2003)
Interleukin-1β stimulates human renal fibroblast proliferation and matrix protein production by means of a transforming growth factor-β-dependent mechanism
DA Vesey et al.
JOURNAL OF LABORATORY AND CLINICAL MEDICINE (2002)
A role for IL-18 in neutrophil activation
BP Leung et al.
JOURNAL OF IMMUNOLOGY (2001)
Share Paper
