Adalimumab in Treating Refractory Livedoid Vasculopathy

Article Dermatology

Efficacy of an anti-TNF-alpha agent in refractory livedoid vasculopathy: a retrospective analysis

Yimeng Gao et al.

Summary: Etanercept therapy is effective for skin lesions and pain, and improves the quality of life in patients with refractory livedoid vasculopathy, especially in rapid pain relief.

JOURNAL OF DERMATOLOGICAL TREATMENT (2022)

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Letter Dermatology

Primary and Secondary Livedoid Vasculopathy: A Report of 2 Cases

Lamia Sabry AboElnasr et al.

AMERICAN JOURNAL OF DERMATOPATHOLOGY (2022)

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Review Dermatology

Livedoid vasculopathy: Clinical course and long-term outcome in Asian patients with a review of the literature

Chuda Rujitharanawong et al.

Summary: LV is a rare vascular disorder with limited data on Thai population. Treatment mainly involves anti-inflammatory drugs, antiplatelet drugs, and immunosuppressants, with promising results from combination therapy with PUVA or anticoagulants. Kaplan-Meier analysis showed disease improvement in 38.5-57.9% of patients at 1-3 years.

DERMATOLOGIC THERAPY (2021)

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Review Medicine, General & Internal

Diagnosis and management of leukocytoclastic vasculitis

Paolo Fraticelli et al.

Summary: Leukocytoclastic vasculitis is a type of small vessel vasculitis characterized by palpable purpura, which can be caused by various factors such as medications, infections, or malignancy. Diagnosis and treatment involve a comprehensive workup and symptom management, with appropriate therapy based on the underlying cause and severity of the condition.

INTERNAL AND EMERGENCY MEDICINE (2021)

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Article Dermatology

Use of Fertility Drugs and Risk of Malignant Melanoma: Results from a Large Danish Population-Based Cohort Study

Linn Freund et al.

Summary: The study found that the use of fertility drugs was associated with a modestly increased risk of malignant melanoma, especially among women with fertility challenges. The specific types of fertility drugs were also found to be possibly linked to an increased risk of malignant melanoma, although the association did not reach statistical significance.

JOURNAL OF INVESTIGATIVE DERMATOLOGY (2021)

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Article Environmental Sciences

Anti-TNF-Related Leukocytoclastic Vasculitis in Ulcerative Colitis: A Case Report

Valentina Giorgio et al.

Summary: The development of drugs targeting TNF-alpha has revolutionized the treatment of inflammatory bowel diseases but also led to a better understanding of their adverse effects on the skin. This case report highlights a rare steroid-dependent form of leukocytoclastic vasculitis induced by an anti-TNF-alpha agent in a young woman with ulcerative colitis, with skin manifestations improving after discontinuing the drug and starting second-line immunosuppressant therapy. It underscores the importance of developing specific recommendations for managing skin reactions induced by anti-TNF-alpha drugs.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2021)

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Letter Pediatrics