4.5 Review

Electroosmosis in nanopores: computational methods and technological applications

Journal

ADVANCES IN PHYSICS-X
Volume 7, Issue 1, Pages -

Publisher

TAYLOR & FRANCIS LTD
DOI: 10.1080/23746149.2022.2036638

Keywords

Electroosmotic flow; molecular dynamics; PNP-NS; mesoscale models; nanopore sensing

Funding

  1. European Research Council (ERC) under the European Union [803213]
  2. Deutsche Forschungsgemeinschaft [416229255 SFB 1411]
  3. MRSEC National Science Foundation [DMR-1420073]
  4. Marie Sklodowska-Curie Actions [839225]
  5. Marie Curie Actions (MSCA) [839225] Funding Source: Marie Curie Actions (MSCA)
  6. European Research Council (ERC) [803213] Funding Source: European Research Council (ERC)

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This article reviews recent progress on computational techniques for the analysis of electroosmosis and discusses technological applications, particularly for nanopore sensing devices.
Electroosmosis is a fascinating effect where liquid motion is induced by an applied electric field. Counter ions accumulate in the vicinity of charged surfaces, triggering a coupling between liquid mass transport and external electric field. In nanofluidic technologies, where surfaces play an exacerbated role, electroosmosis is thus of primary importance. Its consequences on transport properties in biological and synthetic nanopores are subtle and intricate. Thorough understanding is therefore challenging yet crucial to fully assess the mechanisms at play. Here, we review recent progress on computational techniques for the analysis of electroosmosis and discuss technological applications, in particular for nanopore sensing devices.

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