Synthesis of selenated γ-lactones via photoredox-catalyzed selenylation and ring closure of alkenoic acids with diselenides

A photoredox-catalyzed selenylation and ring closure sequences of alkenoic acid derivatives are achieved. This transformation is efficiently accelerated using an inexpensive Rhodamine 6G as an organophotocatalyst under visible light irradiation. The present method affords efficient and practical access to structurally diverse selenated gamma-lactones in moderate to high yields.

Automated summary

A photoredox-catalyzed selenylation and ring closure reaction of alkenoic acid derivatives has been achieved using Rhodamine 6G as an organophotocatalyst under visible light irradiation. The method provides efficient and practical access to structurally diverse selenated gamma-lactones in moderate to high yields.