4.4 Article

Human Herpesvirus-6 Detection in Cerebrospinal Fluid on the BioFire FilmArray Meningitis/Encephalitis Panel in a High Human Immunodeficiency Virus-Prevalence African Setting

Journal

OPEN FORUM INFECTIOUS DISEASES
Volume 9, Issue 7, Pages -

Publisher

OXFORD UNIV PRESS INC
DOI: 10.1093/ofid/ofac229

Keywords

cerebrospinal fluid; encephalitis; HIV; human herpesvirus-6; meningitis

Funding

  1. NIHR [RP-2017-08-ST2-012]
  2. bioMerieux
  3. National Institutes of Health Research (NIHR) [RP-2017-08-ST2-012] Funding Source: National Institutes of Health Research (NIHR)

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The prevalence and clinical relevance of human herpesvirus-6 (HHV-6) in cerebrospinal fluid (CSF) using multiplex polymerase chain reaction (PCR) testing in high human immunodeficiency virus (HIV)-prevalence African settings are still unknown. This study describes the clinical and laboratory characteristics of 13 patients with HHV-6 CSF PCR positivity in Botswana.
The prevalence and clinical relevance of human herpesvirus-6 (HHV-6) detection in cerebrospinal fluid (CSF) using multiplex polymerase chain reaction (PCR) testing in patients with suspected meningoencephalitis in high human immunodeficiency virus-prevalence African settings are not known. We describe the clinical and laboratory characteristics of 13 patients with HHV-6 CSF PCR positivity in Botswana.

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