4.7 Review

Clays as Vehicles for Drug Photostability

Journal

PHARMACEUTICS
Volume 14, Issue 4, Pages -

Publisher

MDPI
DOI: 10.3390/pharmaceutics14040796

Keywords

clay minerals; pharmaceuticals; hybrids; photosensitivity; stability; biotechnological application

Funding

  1. Junta de Andalucia [PT18 RT 3786]

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This study summarizes the information on the stability of drugs incorporated into different clay minerals, focusing on their photostability and potential in biological applications. It highlights the wide range of applications and the promising future of clay minerals in biotechnological research.
Clay minerals are often used due to their high adsorption capacity, which has sparked interest in their biological applications to stabilize drugs and pharmaceutical products. This research aims to summarize information about the stability of drugs, cosmetics, dermocosmetics, and pharmaceutical compounds incorporated in the structure of different clay minerals. The databases used to search the articles were Web of Science, Scopus, PubMed, and Science Direct. Photostabilization of these compounds is reviewed and its importance demonstrated. For biological applications, the increase in solubility and bioavailability of clay minerals has proven useful for them as drug carriers. While their natural abundance, low toxicity, and accessible cost have contributed to classical applications of clay minerals, a wide range of interesting new applications may be facilitated, mainly through incorporating different organic molecules. The search for new functional materials is promising to challenge research on clay minerals in biological or biotechnological approaches.

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