4.7 Review

Topical Probiotics: More Than a Skin Deep

Journal

PHARMACEUTICS
Volume 14, Issue 3, Pages -

Publisher

MDPI
DOI: 10.3390/pharmaceutics14030557

Keywords

probiotics; inflammatory; microorganisms; dermatitis

Funding

  1. Annual Funding track by the Deanship of Scientific Research, Vice Presidency for Graduate Studies and Scientific Research, King Faisal University, Saudi Arabia

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This review discusses the impact of topical probiotics on skin health and diseases, particularly in inflammatory skin conditions and wound healing. A thorough understanding of the relationship between probiotics and the skin is crucial for designing novel therapeutic approaches.
Skin, an exterior interface of the human body is home to commensal microbiota and also acts a physical barrier that protects from invasion of foreign pathogenic microorganisms. In recent years, interest has significantly expanded beyond the gut microbiome to include the skin microbiome and its influence in managing several skin disorders. Probiotics play a major role in maintaining human health and disease prevention. Topical probiotics have demonstrated beneficial effects for the treatment of certain inflammatory skin diseases such as acne, rosacea, psoriasis etc., and also found to have a promising role in wound healing. In this review, we discuss recent insights into applications of topical probiotics and their influence on health and diseases of the skin. Patents, commercially available topical probiotics, and novel probiotic impregnated fabrics have been emphasized. A thorough understanding of the relationship between probiotics and the skin microbiome is important for designing novel therapeutic approaches in using topical probiotics.

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