Journal
FRONTIERS IN ONCOLOGY
Volume 12, Issue -, Pages -Publisher
FRONTIERS MEDIA SA
DOI: 10.3389/fonc.2022.854437
Keywords
sellar ATRT; endoscopic endonasal surgery; hystopathological features; multimodal approach; molecular biology
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Atypical teratoid rhabdoid tumor is a rare lesion that mainly occurs in children, with a male preponderance up to 3 years of age, and more than 50% of cases occurring in the cerebellum. This report describes four new cases of sellar AT/RTs, highlighting the clinical, radiological, and pathological features of these rare lesions, with a focus on the possibility of early diagnosis and appropriate therapeutic strategies.
Atypical teratoid rhabdoid tumor is a rare lesion that occurs mainly in children can be supratentorial or infratentorial and it accounts for 1-2% of pediatric brain tumors and over 10% of central nervous system (CNS) tumors in infants, with a male preponderance up to 3 years of age, more than 50% of these occur in the cerebellum. In this report we describe four new cases of sellar AT/RTs underwent endoscopic endonasal approach and different adjuvant therapies. Our aim is to report the clinical, radiological and pathological features of these rare lesions, focusing on the possibility to perform an early diagnosis and appropriate therapeutic strategy.
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