Journal
JOURNAL OF BREAST CANCER
Volume 19, Issue 3, Pages 324-329Publisher
KOREAN BREAST CANCER SOC
DOI: 10.4048/jbc.2016.19.3.324
Keywords
Biomarkers; Breast neoplasms; Human epidermal growth factor receptor 2; Linitis plastica; Neoplasm metastasis
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Breast cancer metastases to the gastrointestinal tract are very rare occurrences. Among the histological subtypes of breast cancer, invasive lobular carcinomas have a high capacity of metastasis to uncommon sites including the stomach. Conversely, there has not been sufficient evidence supporting the gastric metastasis of invasive ductal carcinoma. Herein, we report a unique case of metastatic ductal breast carcinoma mimicking primary linitis plastica in a male patient, particularly focusing on the clinical and pathological features of presentation. Moreover, we propose a immunohistochemical panel of selected antibodies including those for cytokeratin 20, cytokeratin 7, estrogen receptor, progesterone receptor, E-cadherin, gross cystic disease fluid protein 15, and GATA binding protein 3 for an accurate differential diagnosis.
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