Related references
Note: Only part of the references are listed.Epigenetic Regulation of Cellular Senescence
Jack Crouch et al.
CELLS (2022)
Nuclear lamins: Structure and function in mechanobiology
Amir Vahabikashi et al.
APL BIOENGINEERING (2022)
Molecular models of LINC complex assembly at the nuclear envelope
Zeinab Jahed et al.
JOURNAL OF CELL SCIENCE (2021)
Nesprin-1 impact on tumorigenic cell phenotypes
Ilknur Sur-Erdem et al.
MOLECULAR BIOLOGY REPORTS (2020)
Telomeres and Telomere Length: A General Overview
Nalini Srinivas et al.
CANCERS (2020)
Spatiotemporal Mislocalization of Nuclear Membrane-Associated Proteins in γ-Irradiation-Induced Senescent Cells
Svobodova Kovarikova Alena et al.
CELLS (2020)
Targeting the Wnt/β-catenin signaling pathway in cancer
Ya Zhang et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2020)
DNA-PKcs: A Multi-Faceted Player in DNA Damage Response
Xiaoqiao Yue et al.
FRONTIERS IN GENETICS (2020)
The impact of oxidative DNA damage and stress on telomere homeostasis
Ryan P. Barnes et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2019)
The Driving Force: Nuclear Mechanotransduction in Cellular Function, Fate, and Disease
Melanie Maurer et al.
Annual Review of Biomedical Engineering (2019)
At the Beginning of the End and in the Middle of the Beginning: Structure and Maintenance of Telomeric DNA Repeats and Interstitial Telomeric Sequences
Anna Y. Aksenova et al.
GENES (2019)
The Emerging Roles of TERRA in Telomere Maintenance and Genome Stability
Nicole Bettin et al.
CELLS (2019)
Accumulation of Progerin Affects the Symmetry of Cell Division and Is Associated with Impaired Wnt Signaling and the Mislocalization of Nuclear Envelope Proteins
Agustin Sola-Carvajal et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2019)
Mitochondrial Homeostasis and Cellular Senescence
Panagiotis V. S. Vasileiou et al.
CELLS (2019)
Mechanosensing at the Nuclear Envelope by Nuclear Pore Complex Stretch Activation and Its Effect in Physiology and Pathology
F. Donnaloja et al.
FRONTIERS IN PHYSIOLOGY (2019)
Dying under pressure: cellular characterisation and in vivo functions of cell death induced by compaction
Leo Valon et al.
BIOLOGY OF THE CELL (2019)
Radiation-induced unrepairable DSBs: their role in the late effects of radiation and possible applications to biodosimetry
Asao Noda
JOURNAL OF RADIATION RESEARCH (2018)
Cell death mechanisms of the anti-cancer drug etoposide on human cardiomyocytes isolated from pluripotent stem cells
Harshal Nemade et al.
ARCHIVES OF TOXICOLOGY (2018)
Cyclic mechanical tension reinforces DNA damage and activates the p53-p21-Rb pathway to induce premature senescence of nucleus pulposus cells
Chencheng Feng et al.
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2018)
Diminished Canonical β-Catenin Signaling During Osteoblast Differentiation Contributes to Osteopenia in Progeria
Ji Young Choi et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2018)
Hallmarks of Cellular Senescence
Alejandra Hernandez-Segura et al.
TRENDS IN CELL BIOLOGY (2018)
Ionizing Radiation-Induced Cellular Senescence in Normal, Non-transformed Cells and the Involved DNA Damage Response: A Mini Review
Mengqian Li et al.
FRONTIERS IN PHARMACOLOGY (2018)
Disrupting the LINC complex in smooth muscle cells reduces aortic disease in a mouse model of Hutchinson-Gilford progeria syndrome
Paul H. Kim et al.
SCIENCE TRANSLATIONAL MEDICINE (2018)
Nesprins and Lamins in Health and Diseases of Cardiac and Skeletal Muscles
Alexandre Janin et al.
FRONTIERS IN PHYSIOLOGY (2018)
Mechanical stress influences the viability and morphology of human parametrial ligament fibroblasts
Ming Hu et al.
MOLECULAR MEDICINE REPORTS (2017)
Chemical screening identifies ATM as a target for alleviating senescence
Hyun Tae Kang et al.
NATURE CHEMICAL BIOLOGY (2017)
Shared molecular and cellular mechanisms of premature ageing and ageing-associated diseases
Nard Kubben et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2017)
High-magnitude compression accelerates the premature senescence of nucleus pulposus cells via the p38 MAPK-ROS pathway
Pei Li et al.
ARTHRITIS RESEARCH & THERAPY (2017)
Aged induced pluripotent stem cell (iPSCs) as a new cellular model for studying premature aging
Stefania Petrini et al.
AGING-US (2017)
Effects of concomitant inactivation of p53 and pRb on response to doxorubicin treatment in breast cancer cell lines
Johanna Huun et al.
CELL DEATH DISCOVERY (2017)
Lamin in inflammation and aging
Joseph R. Tran et al.
CURRENT OPINION IN CELL BIOLOGY (2016)
Specific lipofuscin staining as a novel biomarker to detect replicative and stress-induced senescence. A method applicable in cryo-preserved and archival tissues
EA Georgakopoulou et al.
Aging-US (2016)
Nesprin-2-dependent ERK1/2 compartmentalisation regulates the DNA damage response in vascular smooth muscle cell ageing
D. T. Warren et al.
CELL DEATH AND DIFFERENTIATION (2015)
Loss of MT1-MMP causes cell senescence and nuclear defects which can be reversed by retinoic acid
Ana Gutierrez-Fernandez et al.
EMBO JOURNAL (2015)
Cell Autonomous and Non-Autonomous Effects of Senescent Cells in the Skin
Marco Demaria et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2015)
Embryonic expression of the common progeroid lamin A splice mutation arrests postnatal skin development
Tomas McKenna et al.
AGING CELL (2014)
Aged iPSCs display an uncommon mitochondrial appearance and fail to undergo in vitro neurogenesis
Andrea Masotti et al.
AGING-US (2014)
Modelling the onset of senescence at the G1/S cell cycle checkpoint
Jose C. M. Mombach et al.
BMC GENOMICS (2014)
Oncogene-induced reactive oxygen species fuel hyperproliferation and DNA damage response activation
M. Ogrunc et al.
CELL DEATH AND DIFFERENTIATION (2014)
Dysregulated interactions between lamin A and SUN1 induce abnormalities in the nuclear envelope and endoplasmic reticulum in progeric laminopathies
Zi-Jie Chen et al.
JOURNAL OF CELL SCIENCE (2014)
A role for nuclear envelope-bridging complexes in homology-directed repair
Rebecca K. Swartz et al.
MOLECULAR BIOLOGY OF THE CELL (2014)
The role of senescent cells in ageing
Jan M. van Deursen
NATURE (2014)
Nesprins in health and disease
Sarah Cartwright et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2014)
Genomes of replicatively senescent cells undergo global epigenetic changes leading to gene silencing and activation of transposable elements
Marco Cecco et al.
AGING CELL (2013)
Aging, Cellular Senescence, and Cancer
Judith Campisi
ANNUAL REVIEW OF PHYSIOLOGY, VOL 75 (2013)
The Histone Mark H3K36me3 Regulates Human DNA Mismatch Repair through Its Interaction with MutSα
Feng Li et al.
CELL (2013)
Programmed Cell Senescence during Mammalian Embryonic Development
Daniel Munoz-Espin et al.
CELL (2013)
Senescence Is a Developmental Mechanism that Contributes to Embryonic Growth and Patterning
Mekayla Storer et al.
CELL (2013)
ATM kinase enables the functional axis of YAP, PML and p53 to ameliorate loss of Werner protein-mediated oncogenic senescence
F. Fausti et al.
CELL DEATH AND DIFFERENTIATION (2013)
The diverse functional LINCs of the nuclear envelope to the cytoskeleton and chromatin
Andrea Rothballer et al.
CHROMOSOMA (2013)
Nuclear Mechanics and Mechanotransduction in Health and Disease
Philipp Isermann et al.
CURRENT BIOLOGY (2013)
Lamin B1 fluctuations have differential effects on cellular proliferation and senescence
Oliver Dreesen et al.
JOURNAL OF CELL BIOLOGY (2013)
A mammalian KASH domain protein coupling meiotic chromosomes to the cytoskeleton
Henning F. Horn et al.
JOURNAL OF CELL BIOLOGY (2013)
Lysosome-mediated processing of chromatin in senescence
Andre Ivanov et al.
JOURNAL OF CELL BIOLOGY (2013)
Parkin overexpression during aging reduces proteotoxicity, alters mitochondrial dynamics, and extends lifespan
Anil Rana et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation
Joe Swift et al.
SCIENCE (2013)
Prelamin A causes progeria through cell-extrinsic mechanisms and prevents cancer invasion
Jorge de la Rosa et al.
NATURE COMMUNICATIONS (2013)
The contrasting roles of lamin B1 in cellular aging and human disease
Oliver Dreesen et al.
NUCLEUS-AUSTIN (2013)
Small molecules, inhibitors of DNA-PK, targeting DNA repair, and beyond
David Davidson et al.
FRONTIERS IN PHARMACOLOGY (2013)
Accumulation of the Inner Nuclear Envelope Protein Sun1 Is Pathogenic in Progeric and Dystrophic Laminopathies
Chia-Yen Chen et al.
CELL (2012)
Nesprin interchain associations control nuclear size
Wenshu Lu et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2012)
Inner Nuclear Envelope Proteins SUN1 and SUN2 Play a Prominent Role in the DNA Damage Response
Kai Lei et al.
CURRENT BIOLOGY (2012)
Interleukin-22 induces hepatic stellate cell senescence and restricts liver fibrosis in mice
Xiaoni Kong et al.
HEPATOLOGY (2012)
A conserved KASH domain protein associates with telomeres, SUN1, and dynactin during mammalian meiosis
Akihiro Morimoto et al.
JOURNAL OF CELL BIOLOGY (2012)
Lamin B1 loss is a senescence-associated biomarker
Adam Freund et al.
MOLECULAR BIOLOGY OF THE CELL (2012)
Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation
Marzia Fumagalli et al.
NATURE CELL BIOLOGY (2012)
Multiple Novel Nesprin-1 and Nesprin-2 Variants Act as Versatile Tissue-Specific Intracellular Scaffolds
Dipen Rajgor et al.
PLOS ONE (2012)
Cellular senescence induced by CD158d reprograms natural killer cells to promote vascular remodeling
Sumati Rajagopalan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Innate immunosenescence: Effect of aging on cells and receptors of the innate immune system in humans
Rafael Solana et al.
SEMINARS IN IMMUNOLOGY (2012)
Nesprin-3: a versatile connector between the nucleus and the cytoskeleton
Mirjam Ketema et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2011)
Inhibition of activated pericentromeric SINE/Alu repeat transcription in senescent human adult stem cells reinstates self-renewal
Jianrong Wang et al.
CELL CYCLE (2011)
Alteration of Golgi structure in senescent cells and its regulation by a G protein γ subunit
Joon-Ho Cho et al.
CELLULAR SIGNALLING (2011)
The role of nuclear lamin B1 in cell proliferation and senescence
Takeshi Shimi et al.
GENES & DEVELOPMENT (2011)
KASH protein Syne-2/Nesprin-2 and SUN proteins SUN1/2 mediate nuclear migration during mammalian retinal development
Juehua Yu et al.
HUMAN MOLECULAR GENETICS (2011)
Nesprin-3 augments peripheral nuclear localization of intermediate filaments in zebrafish
Ruben Postel et al.
JOURNAL OF CELL SCIENCE (2011)
Cellular senescence controls fibrosis in wound healing
Joon-Il Jun et al.
AGING-US (2010)
The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression
Jean -Philippe Coppe et al.
ANNUAL REVIEW OF PATHOLOGY-MECHANISMS OF DISEASE (2010)
Cardiovascular Pathology in Hutchinson-Gilford Progeria: Correlation With the Vascular Pathology of Aging
Michelle Olive et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2010)
Matrix metalloproteinases: Evolution, gene regulation and functional analysis in mouse models
Miriam Fanjul-Fernandez et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2010)
Matrix Metalloproteinases: Regulators of the Tumor Microenvironment
Kai Kessenbrock et al.
CELL (2010)
Both ERK1 and ERK2 kinases promote G2/M arrest in etoposide-treated MCF7 cells by facilitating ATM activation
Fengxiang Wei et al.
CELLULAR SIGNALLING (2010)
Functional Coupling between the Extracellular Matrix and Nuclear Lamina by Wnt Signaling in Progeria
Lidia Hernandez et al.
DEVELOPMENTAL CELL (2010)
Nesprin 1 is critical for nuclear positioning and anchorage
Jianlin Zhang et al.
HUMAN MOLECULAR GENETICS (2010)
Novel Nuclear Nesprin-2 Variants Tether Active Extracellular Signal-regulated MAPK1 and MAPK2 at Promyelocytic Leukemia Protein Nuclear Bodies and Act to Regulate Smooth Muscle Cell Proliferation
Derek T. Warren et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Mammalian SUN Protein Interaction Networks at the Inner Nuclear Membrane and Their Role in Laminopathy Disease Processes
Farhana Haque et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Nesprin-2 Interacts with α-Catenin and Regulates Wnt Signaling at the Nuclear Envelope
Sascha Neumann et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Dynamic Dependence on ATR and ATM for Double-Strand Break Repair in Human Embryonic Stem Cells and Neural Descendants
Bret R. Adams et al.
PLOS ONE (2010)
Nuclei Take a Position: Managing Nuclear Location
Brian Burke et al.
DEVELOPMENTAL CELL (2009)
Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion
Francis Rodier et al.
NATURE CELL BIOLOGY (2009)
SUN1/2 and Syne/Nesprin-1/2 Complexes Connect Centrosome to the Nucleus during Neurogenesis and Neuronal Migration in Mice
Xiaochang Zhang et al.
NEURON (2009)
Nesprin 4 is an outer nuclear membrane protein that can induce kinesin-mediated cell polarization
Kyle J. Roux et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
SUN1 and SUN2 play critical but partially redundant roles in anchoring nuclei in skeletal muscle cells in mice
Kai Lei et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Increased mechanosensitivity and nuclear stiffness in Hutchinson-Gilford progeria cells: effects of farnesyltransferase inhibitors
Valerie L. R. M. Verstraeten et al.
AGING CELL (2008)
Wnt-signaling and senescence A tug of war in early neoplasia?
Peter D. Adams et al.
CANCER BIOLOGY & THERAPY (2008)
Structural requirements for the assembly of LINC complexes and their function in cellular mechanical stiffness
P. J. Stewart-Hutchinson et al.
EXPERIMENTAL CELL RESEARCH (2008)
Nuclear envelope defects cause stem cell dysfunction in premature-aging mice
Jesus Espada et al.
JOURNAL OF CELL BIOLOGY (2008)
Nesprin-2 Giant (NUANCE) maintains nuclear envelope architecture and composition in skin
Yvonne Lueke et al.
JOURNAL OF CELL SCIENCE (2008)
Nesprin-2 giant safeguards nuclear envelope architecture in LMNA S143F progeria cells
Sebastian Kandert et al.
HUMAN MOLECULAR GENETICS (2007)
Nesprin-1 and -2 are involved in the pathogenesis of Emery-Dreifuss muscular dystrophy and are critical for nuclear envelope integrity
Qiuping Zhang et al.
HUMAN MOLECULAR GENETICS (2007)
Declining p53 function in the aging process: A possible mechanism for the increased tumor incidence in older populations
Zhaohui Feng et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
SUN1 is required for telomere attachment to nuclear envelope and gametogenesis in mice
Xu Ding et al.
DEVELOPMENTAL CELL (2007)
Structure of the human MutSα DNA lesion recognition complex
Joshua J. Warren et al.
MOLECULAR CELL (2007)
Transmembrane protein Sun2 is involved in tethering mammalian meiotic telomeres to the nuclear envelope
Johannes Schmitt et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Hutchinson-Gifford Progeria syndrome: Review of the phenotype
Raoul C. M. Hennekam
AMERICAN JOURNAL OF MEDICAL GENETICS PART A (2006)
Anti-oncogenic role of the endoplasmic reticulum differentially activated by mutations in the MAPK pathway
Christophe Denoyelle et al.
NATURE CELL BIOLOGY (2006)
The inner nuclear membrane protein Emerin regulates β-catenin activity by restricting its accumulation in the nucleus
Ewa Markiewicz et al.
EMBO JOURNAL (2006)
Distinct structural and mechanical properties of the nuclear lamina in Hutchinson-Gilford progeria syndrome
Kris Noel Dahl et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Nuclear lamins: Laminopathies and their role in premature ageing
J. L. V. Broers et al.
PHYSIOLOGICAL REVIEWS (2006)
A pericellular collagenase directs the 3-dimensional development of white adipose tissue
Tae-Hwa Chun et al.
CELL (2006)
Primary and compensatory roles for RB family members at cell cycle gene promoters that are deacetylated and downregulated in doxorubicin-induced senescence of breast cancer cells
JG Jackson et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Progressive vascular smooth muscle cell defects in a mouse model of Hutchinson-Gilford progeria syndrome
R Varga et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Coupling of the nucleus and cytoplasm: role of the LINC complex
M Crisp et al.
JOURNAL OF CELL BIOLOGY (2006)
Accelerated ageing in mice deficient in Zmpste24 protease is linked to p53 signalling activation
I Varela et al.
NATURE (2005)
Genomic instability in laminopathy-based premature aging
BH Liu et al.
NATURE MEDICINE (2005)
Senescence and immortalization: role of telomeres and telomerase
JW Shay et al.
CARCINOGENESIS (2005)
Membrane-type 1 matrix metalloproteinase is required for normal alveolar development
JJ Atkinson et al.
DEVELOPMENTAL DYNAMICS (2005)
Reactive oxygen species as mediators of cellular senescence
R Colavitti et al.
IUBMB LIFE (2005)
Senescent cells, tumor suppression, and organismal aging: Good citizens, bad neighbors
J Campisi
CELL (2005)
Nesprin-2 is a multi-isomeric protein that binds lamin and emerin at the nuclear envelope and forms a subcellular network in skeletal muscle
QP Zhang et al.
JOURNAL OF CELL SCIENCE (2005)
Stromal-epithelial interactions in aging and cancer: senescent fibroblasts alter epithelial cell differentiation
S Parrinello et al.
JOURNAL OF CELL SCIENCE (2005)
Genome-scale expression profiling of Hutchinson-Gilford progeria syndrome reveals widespread transcriptional misregulation leading to mesodermal/mesenchymal defects and accelerated atherosclerosis
AB Csoka et al.
AGING CELL (2004)
Tumor cell traffic through the extracellular matrix is controlled by the membrane-anchored collagenase MT1-MMP
F Sabeh et al.
JOURNAL OF CELL BIOLOGY (2004)
Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21CIP1, but not p16INK4a
U Herbig et al.
MOLECULAR CELL (2004)
Enaptin, a giant actin-binding protein, is an element of the nuclear membrane and the actin cytoskeleton
VC Padmakumar et al.
EXPERIMENTAL CELL RESEARCH (2004)
A DNA damage checkpoint response in telomere-initiated senescence
FD di Fagagna et al.
NATURE (2003)
Lamin A truncation in Hutchinson-Gilford progeria
A De Sandre-Giovannoli et al.
SCIENCE (2003)
A progeroid syndrome in mice is caused by defects in A-type lamins
LC Mounkes et al.
NATURE (2003)
Recurrent de novo point mutations in lamin A cause Hutchinson-Gilford progeria syndrome
M Eriksson et al.
NATURE (2003)
Cancer and aging: a model for the cancer promoting effects of the aging stroma
A Krtolica et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2002)
Zmpste24 deficiency in mice causes spontaneous bone fractures, muscle weakness, and a prelamin A processing defect
MO Bergo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Adriamycin-induced senescence in breast tumor cells involves functional p53 and telomere dysfunction
LW Elmore et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Strategies for MMP inhibition in cancer:: Innovations for the post-trial era
CM Overall et al.
NATURE REVIEWS CANCER (2002)
Defective prelamin A processing and muscular and adipocyte alterations in Zmpste24 metalloproteinase-deficient mice
AM Pendás et al.
NATURE GENETICS (2002)
Smooth muscle cell depletion and collagen types in progeric arteries
WE Stehbens et al.
CARDIOVASCULAR PATHOLOGY (2001)
Impaired endochondral ossification and angiogenesis in mice deficient in membrane-type matrix metalloproteinase I
ZJ Zhou et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)